Relationship Between Different Experimental Measures of Distorted Symptom Perception in Functional Syndrome Patients

Abstract

Objective: Patients with functional somatic syndromes (FSS) show reduced correspondence between induced physiological changes and self-reported symptoms in a rebreathing paradigm, as well as elevated symptoms unrelated to physiological changes after induction of negative affective states in an affective picture viewing paradigm. Detailed results of both paradigms separately were published elsewhere. The main goal of the current report is to describe the relationship between the responses to these two paradigms measuring distortions in symptom perception in a well-described sample of patients with fibromyalgia and/or chronic fatigue syndrome (CFS).Methods: Patients (N=81) with fibromyalgia and/or CFS participated in a test session comprising four well-validated paradigms, including the picture viewing and rebreathing paradigm. Using mixed model analyses, it was tested whether the amount of affective modulation of symptom reporting was related to distorted perception of induced dyspnea. In an exploratory way, we assessed the role of several individual difference variables as moderators.Results: There was no relationship between patients' amount of affective modulation of symptom reporting, as assessed with the picture paradigm, and level of distortion in dyspnea perception, as assessed with the rebreathing paradigm (effect of affective modulation in the subjective recovery from induced dyspnea: F1,70 = 0.16, p = 0.70; time*affective modulation interaction effect: F4,70 = 0.14, p = 0.97). Conclusions:Biased symptom reporting in one paradigm is unrelated to biased symptom reporting in the other paradigm, indicating that distortions in symptom perception in FSS patients is not a trait-like, cross-situationally stable condition, but a versatile dysfunction that is context-dependent.

Manual Lymphatic Drainage Therapy in the Knee Joint Functional Rehabilitation After TKA in Diabetic Knee Osteoarthritis Patients: A Randomized Clinical Trial

“…Manual lymphatic drainage therapy can effectively relieve postoperative knee swelling and pain in patients with diabetic knee osteoarthritis after total knee arthroplasty. And the therapy can also accelerate knee joint function recovery, improve postoperative patient satisfaction, and has a clear effect on promoting postoperative functional rehabilitation [16] of diabetic patients.…”

Somatic symptom distress and ICD-11 prolonged grief in a large intercultural sample

“…In line with the assumption that elevated somatic symptom distress is the consequence of negative affective states are experimental studies showing that the induction of negative affective states (and sadness in particular (Sauer & Witthöft, 2017 ), as well as the presentation of negative affective cues (e.g. pictures), can cause increases in somatic symptom distress (Bogaerts et al, 2010 ; van den Houte et al, 2019 ). In this current study, we have the opportunity to explore the relationship between grief severity and somatic symptom distress in three regions (USA, Cyprus/Greece, Turkey/Iran) as part of a large international collaboration (Killikelly et al, 2023 ).…”