Relationship Between Dual Time Point FDG PET/CT and Clinical Prognostic Indexes in Patients with High Grade Lymphoma: a Pilot Study

Lim, Do Hyoung; Lee, Jai Hyuen

doi:10.1007/s13139-017-0480-y

Cited by 15 publications

(11 citation statements)

References 30 publications

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“…Some studies have reported that RI is related to the biological characteristics of breast cancer [ 9 , 21 , 22 ]. RI has also been reported to be correlated with prognosis in patients with lung cancer, cholangiocarcinoma, and lymphoma [ [23] , [24] , [25] ]. However, only one study has reported a relationship between RI and prognosis in patients with breast cancer [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Dual-phase FDG PET/CT for predicting prognosis in operable breast cancer

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Dual-phase FDG PET/CT for predicting prognosis in operable breast cancer

et al. 2022

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“…Some reported that 18 F-FDG uptake in malignancy continued to increase until approximately 4-5 h after injection, but the uptake decreased in the benign lesion 30 min after the injection [18,28]. Furthermore, the ΔSUV max % was correlated with the grade of malignancy in lung cancer and lymphoma [29,30]. Although the usefulness of ΔSUV max % was generally considered acceptable, few reports have been published on its relationship with the prognosis of breast cancer.…”

Section: Discussionmentioning

confidence: 99%

Dual time point 18F-fluorodeoxyglucose positron emission tomography/computed tomography fusion imaging (18F-FDG PET/CT) in primary breast cancer

et al. 2019

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Background: To evaluate the clinicopathological and prognostic significance of the percentage change between maximum standardized uptake value (SUV max) at 60 min (SUV max 1) and SUV max at 120 min (SUV max 2) (ΔSUV max %) using dual time point 18 F-fluorodeoxyglucose emission tomography/computed tomography (18 F-FDG PET/CT) in breast cancer. Methods: Four hundred and sixty-four patients with primary breast cancer underwent 18 F-FDG PET/CT for preoperative staging. ΔSUV max % was defined as (SUV max 2 − SUV max 1) / SUV max 1 × 100. We explored the optimal cutoff value of SUV max parameters (SUV max 1 and ΔSUV max %) referring to the event of relapse by using receiver operator characteristic curves. The clinicopathological and prognostic significances of the SUV max 1 and ΔSUV max % were analyzed by Cox's univariate and multivariate analyses. Results: The optimal cutoff values of SUV max 1 and ΔSUV max % were 3.4 and 12.5, respectively. Relapse-free survival (RFS) curves were significantly different between high and low SUV max 1 groups (P = 0.0003) and also between high and low ΔSUV max % groups (P = 0.0151). In Cox multivariate analysis for RFS, SUV max 1 was an independent prognostic factor (P = 0.0267) but ΔSUV max % was not (P = 0.152). There was a weak correlation between SUV max 1 and ΔSUV max % (P < 0.0001, R 2 = 0.166). On combining SUV max 1 and ΔSUV max %, the subgroups of high SUV max 1 and high ΔSUV max % showed significantly worse prognosis than the other groups in terms of RFS (P = 0.0002). Conclusion: Dual time point 18 F-FDG PET/CT evaluation can be a useful method for predicting relapse in patients with breast cancer. The combination of SUV max 1 and ΔSUV max % was able to identify subgroups with worse prognosis more accurately than SUV max 1 alone.

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“…Les deux é tudes, explorant les capacité s de l'acquisition retardé e/DTP à diffé rencier des ganglions bé nins d'adé nopathies lymphomateuses, ont montré des ré sultats contradictoires quant à son apport supplé mentaire vs une acquisition classique [153,154] et d'autres articles ont montré des liens entre les paramè tres issus de l'acquisition DTP et l'indice de prolifé ration, l'index pronostique international et le bilan d'extension tumoral dont la pré sence d'une atteinte extra-ganglionnaire [156,157].…”

Section: Caracte´risation Malin/be´ninunclassified