Relationship between Dyspnea in Daily Life and Psycho-physiologic State in Patients with Chronic Obstructive Pulmonary Disease during Long-Term Domiciliary Oxygen Therapy.

Relationship Between Depression in Patients With COPD and the Percent of Predicted FEV1, BODE Index, and Health-Related Quality of Life

“…Furthermore, based on reports on the prevalence of depression in Japan, Mishima et al observed a prevalence of 35% among outpatients with COPD who were receiving LTOT. 9 Although our study showed a high prevalence of depression (48.6%), the reasons for this high rate may include the older age of the subjects (mean 72.7 years), the fact that our subjects were in-patients, and that a substantial proportion were receiving LTOT. Furthermore, Gudmundsson et al 6 and Mishima et al 9 used the Hospital Anxiety and Depression scale (HADS), 29 which may account for the difference in prevalence rates.…”

“…This negative spiral is thought not only to result in poor physical function but also to have an adverse impact on psycho-logical status, leading to a decrease in quality of life (QOL), and it is well documented that this spiral leads to anxiety and depression among many COPD patients. [3][4][5][6][7][8][9][10] Furthermore, because the presence of depression may be associated with exacerbations of COPD and/or an increase in mortality, [11][12][13][14][15] therapeutic interventions that target psychological impairments are considered necessary.…”

Depression in Japanese Patients With Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study

“…In 1996, Mishima reported that the prevalence of depression was as low as 19% 23 ; however, the cutoff value (10 points on the Hospital Anxiety and Depression scale) is higher than the usually used cutoff of 8 points. 20 Among European countries the prevalence of depression is especially high in the United Kingdom (see Table 4).…”

“…12 Several risk factors are well known to predict depression in COPD patients: female, 7,13 current smoking, 7,12,14 poor quality of life, 9,12-14 long-term oxygen therapy (LTOT), 15 living alone, 16 and low social status. 7 Studies in North America and Europe have evaluated the association between depression and physical factors such as percent-of-predicted FEV 1 , 6-min walk distance (6MWD), and Modified Medical Research Council (MMRC) dyspnea score, 3,13,14,[16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] but few studies have focused on the association between depression and COPD in Asians. Compared to whites, Asians generally exhibited elevated levels of depression.…”

Health-related quality of life in individuals with chronic obstructive pulmonary disease

“…Finally, the relationship observed here between breathlessness and hopelessness and anxiety is also consistent with other findings. 31,36,[47][48][49] Reduced activities of daily living and physical impairment had significant impacts on the physical health component of HRQOL. This is in consistent with the work of Schrier and colleagues 15 and Viramontes and O'Brien, 18 who found an association between reduced activities of daily living and decreased HRQOL.…”