Relationship between ED and depression among middle-aged and elderly men in Korea: Hallym aging study

Jy, Jeong; Sk, Lee; Yw, Kang; Jang, Soong-Nang; Yj, Choi; Kim, Do-Hyung

doi:10.1038/ijir.2011.32

Cited by 19 publications

(27 citation statements)

References 33 publications

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“…In within-persons analyses, we observed that increases in depression scores were significantly associated with increases in erectile dysfunction, which is consistent with the literature. In the general population (Jeong et al, 2011; Lotti et al, 2012) and studies of opioid-dependent men (Hallinan et al, 2008; Quaglio et al, 2008), depressive symptoms are often associated with increased symptoms of erectile dysfunction. Although the exact mechanism for this is unknown, psychological causes have been postulated (Jeong et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Change in symptoms of erectile dysfunction in depressed men initiating buprenorphine therapy

Cioe

Anderson

Stein

2013

Journal of Substance Abuse Treatment

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Aims The aim of this study is to describe the change in erectile dysfunction (ED) symptoms in the first 12 weeks of outpatient buprenorphine therapy. Background Erectile dysfunction is highly prevalent in men who use illicit opioids when compared with the general population. To date, no study has examined ED symptoms over time in men initiating buprenorphine therapy for opioid dependence. Methods A randomized, double blind, placebo-controlled trial was conducted to determine whether escitalopram treatment of depressive symptoms begun 1 week prior to buprenorphine induction would improve treatment retention. Male patients completed the International Index of Erectile Function scale at baseline prior to induction and monthly thereafter. A score of 25 or less on the erectile function domain (range 1–30) is considered indicative of erectile dysfunction. Findings A total of 111 male subjects enrolled: mean age 38.5 (± 9.7) years, 80.1% non-Hispanic Caucasian; 67.3% reported heroin as their opioid of choice. Mean IIEF at baseline was 20.4 (± 10.5). At baseline, 44.1% of the entire cohort had erectile dysfunction; among those who identified as sexually active at baseline, 26.1% had ED. Baseline erectile function was inversely and significantly correlated with age (r = −.27, p = .006), but was not associated significantly with race, heroin use, years of opioid use, smoking, or hazardous use of alcohol. Compared to baseline, mean erectile function was significantly improved (p = .001) at 3 months, and sexual desire (p = .002) improved significantly at both 2- and 3-month assessments. Conclusion Erectile dysfunction is highly prevalent in depressed males using illicit opioids. Men who remain in buprenorphine treatment for 3 months show improvement in erectile function and sexual desire.

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Section: Discussionmentioning

confidence: 99%

Change in symptoms of erectile dysfunction in depressed men initiating buprenorphine therapy

Cioe

Anderson

Stein

2013

Journal of Substance Abuse Treatment

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“…The most investigated MSDs included ED, various types of ED, ejaculation dysfunctions (PE and DE), and HSDD in both the Asian and European studies. A total of 19 Asian studies presented the prevalence of ED (Çayan et al, 2017;Chung et al, 2015;Ghalayini et al, 2010;Hao et al, 2011;Huang et al, 2014;Hwang et al, 2010;Jeong et al, 2011;Khoo et al, 2008;Kim et al, 2009;Liu et al, 2010;Permpongkosol et al, 2008;Quek et al, 2008;Rao et al, 2015;Tang et al, 2015;…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Epidemiology of Male Sexual Dysfunction in Asian and European Regions: A Systematic Review

et al. 2020

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Male sexual dysfunctions (MSDs) often remain undiagnosed and untreated in Asia compared to Europe due to conservative cultural and religious beliefs, socioeconomic conditions, and lack of awareness. There is a tendency for the use of traditional medicines and noncompliance with and reduced access to modern healthcare. The present systematic review compared the incidence and factors of MSD in European and Asian populations. English language population/community-based original articles on MSDs published in MEDLINE from 2008 to 2018 were retrieved. A total of 5392 studies were retrieved, of which 50 (25 Asian and 25 European) were finally included in this review. The prevalence of erectile dysfunction (ED) (0%–95.0% vs. 0.9%–88.8%), low satisfaction (3.2%–37.6% vs. 4.1%–28.3%), and hypoactive sexual desire disorder (HSDD) (0.7%–81.4 vs. 0%–65.5%) was higher in Asian than in European men, whereas the prevalence of anorgasmia (0.4% vs. 3%–65%) was lower in Asian than in European men. Age was an independent positive factor of MSD. In European men over 60 years old, the prevalence of premature ejaculation (PE) decreased. The prevalence of MSD was higher in questionnaires than in interviews. The significant factors were age, single status, low socioeconomic status, poor general health, less physical activity, cardiovascular diseases, diabetes, obesity, lower urinary tract symptoms, prostatitis, anxiety, depression and alcohol, tobacco, and drug use. The prevalence of MSD differed slightly in Asian and European men. There is a need to conduct large studies on the various Asian populations for the effective management of MSD.

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“…A sample of 203 subjects aged between 45 and 74 years old was assessed through the administration of International Index of Erectile Function 5 (IIEF-5) and Geriatric Depression Scale (GDS), in order to define the presence of a relationship between depressive symptoms and ED severity. ED was shown to be closely linked to depressive symptoms, together with some factors such as life style, smoking, and alcohol [55]. …”

Section: Ed In Elderly Men Affected With Psychiatric Disordersmentioning

confidence: 99%

Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives

Gareri¹,

Castagna

Francomano

et al. 2014

International Journal of Endocrinology

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Erectile dysfunction (ED) is one of the most common chronic diseases affecting men and its prevalence increases with aging. It is also the most frequently diagnosed sexual dysfunction in the older male population. A number of different diseases potentially worsening sexual function may occur in elderly people, together with polypharmacy. Related causes of ED are variable and can include arterial, neurogenic, hormonal, cavernosal, iatrogenic, and psychogenic causes. The aim of the present review was to examine the main aspects of erectile dysfunction going through epidemiology and pathophysiology and revise most of ED in elderly disabled men and in those affected with psychiatric disorders. Lastly we tried to focus on the main aspects of nonpharmacological and pharmacological treatments of ED and the recreational use in the elderly. Phosphodiesterase-5 inhibitors (PDE5-I) are commonly used for on-demand or chronic treatment of ED. It is widely known that PDE5-I have lower response rates in older men than in younger patients, but they have the advantages of ease of use and excellent safety profile, also in the elderly. The old and new PDE5-I as well as the alternative treatments for ED are extensively discussed.

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Relationship between ED and depression among middle-aged and elderly men in Korea: Hallym aging study

Cited by 19 publications

References 33 publications

Change in symptoms of erectile dysfunction in depressed men initiating buprenorphine therapy

Change in symptoms of erectile dysfunction in depressed men initiating buprenorphine therapy

Epidemiology of Male Sexual Dysfunction in Asian and European Regions: A Systematic Review

Erectile Dysfunction in the Elderly: An Old Widespread Issue with Novel Treatment Perspectives

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