2012
DOI: 10.1118/1.3679339
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Relationship between electron density and effective densities of body tissues for stopping, scattering, and nuclear interactions of proton and ion beams

Abstract: Purpose: In treatment planning of charged-particle radiotherapy, patient heterogeneity is conventionally modeled as variable-density water converted from CT images to best reproduce the stopping power, which may lead to inaccuracies in the handling of multiple scattering and nuclear interactions. Although similar conversions can be defined for these individual interactions, they would be valid only for specific CT systems and would require additional tasks for clinical application. This study aims to improve t… Show more

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Cited by 42 publications
(49 citation statements)
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“…The proposed method to compute the SPR from dual‐energy data in the projection domain is an adaptation of the two‐steps procedure proposed by Farace in the image domain. It consists of two steps: first, determination of the RED image through the two‐material decomposition method proposed by Alvarez and Macovski implemented in the projection domain; and second, determination of the SPR image using the poly‐lines relations proposed by Kanematsu et al…”
Section: Methodsmentioning
confidence: 99%
See 3 more Smart Citations
“…The proposed method to compute the SPR from dual‐energy data in the projection domain is an adaptation of the two‐steps procedure proposed by Farace in the image domain. It consists of two steps: first, determination of the RED image through the two‐material decomposition method proposed by Alvarez and Macovski implemented in the projection domain; and second, determination of the SPR image using the poly‐lines relations proposed by Kanematsu et al…”
Section: Methodsmentioning
confidence: 99%
“…The reconstructed RED values were directly converted into SPR through the piecewise linear relations of the RED and the ratio between SPR and RED of human tissues as suggested by Kanematsu . To reproduce Fig.…”
Section: Methodsmentioning
confidence: 99%
See 2 more Smart Citations
“…However, this approximation may cause dosimetric errors due to alteration of the radiation because the effective density differs for multiple scattering and nuclear interactions. 4 Dosimetric water equivalence, which is evaluated by uniformity of effective densities for relevant interactions, is essential to energy degrading of charged-particle beams for range shifting, range compensation, and dosimetry.…”
Section: Introductionmentioning
confidence: 99%