Relationship Between Emotional Intelligence, Psychological Status and Mean Ambulatory Blood Pressure Level in Patients With Arterial Hypertension: PP.3.126

Андреева, Г.; Деев, А. Д.; Горбунов, В. М.; Lyusin, D.; Лерман, О. В.

doi:10.1097/01.hjh.0000378450.39176.90

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“…Finally, since excessive perception of their own or other people's emotions can lead to increased clinical and ambulatory blood pressure levels ( 40 ), the measurement of emotional/psychological status should be regarded in future studies. Moreover, the sample size might be considered a potential limitation of the present study because different conditions in hypertensive subjects (such as obesity and others) could potentially produce variations in terms of inflammatory and redox status parameters in different studies.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory cytokines and plasma redox status responses in hypertensive subjects after heat exposure

Fonseca

Mendonça

Ribeiro

et al. 2016

Braz J Med Biol Res

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Hypertension is characterized by a pro-inflammatory status, including redox imbalance and increased levels of pro-inflammatory cytokines, which may be exacerbated after heat exposure. However, the effects of heat exposure, specifically in individuals with inflammatory chronic diseases such as hypertension, are complex and not well understood. This study compared the effects of heat exposure on plasma cytokine levels and redox status parameters in 8 hypertensive (H) and 8 normotensive (N) subjects (age: 46.5±1.3 and 45.6±1.4 years old, body mass index: 25.8±0.8 and 25.6±0.6 kg/m2, mean arterial pressure: 98.0±2.8 and 86.0±2.3 mmHg, respectively). They remained at rest in a sitting position for 10 min in a thermoneutral environment (22°C) followed by 30 min in a heated environmental chamber (38°C and 60% relative humidity). Blood samples were collected before and after heat exposure. Plasma cytokine levels were measured using sandwich ELISA kits. Plasma redox status was determined by thiobarbituric acid reactive substances (TBARS) levels and ferric reducing ability of plasma (FRAP). Hypertensive subjects showed higher plasma levels of IL-10 at baseline (P<0.05), although levels of this cytokine were similar between groups after heat exposure. Moreover, after heat exposure, hypertensive individuals showed higher plasma levels of soluble TNF receptor (sTNFR1) and lower TBARS (P<0.01) and FRAP (P<0.05) levels. Controlled hypertensive subjects, who use angiotensin-converting-enzyme inhibitor (ACE inhibitors), present an anti-inflammatory status and balanced redox status. Nevertheless, exposure to a heat stress condition seems to cause an imbalance in the redox status and an unregulated inflammatory response.

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Section: Discussionmentioning

confidence: 99%