Relationship between genotoxicity and oxidative stress induced by mercury on common carp (Cyprinus carpio) tissues

Potential Effects of Heavy Metals Bioaccumulation on Oxidative stress Enzymes of Mediterranean clam Ruditapes decussatus

“…The current results indicated, the increasing level concentrations of Pb, Cd, Zn, Mn and Cu in seawater and soft tissues of Site I were higher than Site II and this may be due to increasing in the contamination resources, which mainly from the industrial effluents, domestic, sewage effluents and wastewater, that effect directly or indirectly on the physiological functions of aquatic organisms and human being health (Arafa and Ali, 2008). Early studies reported that, the heavy metals are entering into water effluents through industrial, agricultural and municipal wastes and affects the rate of reproductive system of aquatic organisms leading to a gradual extinction of their generations; also, disturb their physiological functions (Shenai et al, 2017;García-Medina et al, 2017).…”

Effect of Lead Graded Doses in <i>Mactra Corallina</i> Gills: Antioxidants Status, Cholinergic Function and Histopathological Studies

“…It's known that cellular damages induced by metals are the result of ROS overproduction and the compensatory response from endogenous and antioxidants such as enzymatic and nonenzymatic systems [8]. Among them, superoxide dismutase (SOD) is a catalyzer compound that converts superoxide radicals to hydrogen peroxide which was transformed in to H 2 O via glutathione peroxidase (GPx) and catalase (CAT) [32]. In all PbCl 2 treated gills, the decrease of GPx and SOD activities were observed as compared to the control.…”

Preliminary Genotoxicity Assessment of Cadmium, Lead, and Mercury on Different Planktonic Organisms

“…Some authors have suggested [37,38] that DNA can offer abundant binding sites for Cd (mainly N7 centers in adenine and guanine) which cause breaks and other related DNA damage. Besides, oxidative stress, ions of Hg also might bind to DNA and produce strand breaks and DNA-DNA crosslinks, as well as inhibition of DNA repair [39,40]. In relation to lead, a revision made by García-Lestón et al [41] includes evidence of genotoxicity induced possibly through inhibition of DNA repair or free radical production.…”