Relationship between handgrip strength, depression and cognitive functioning among older adults: Evidence from longitudinal ageing study in India

Abstract

Background Handgrip strength (HGS) is a frequent and general indicator of muscle strength and it may affect several aspects of mental health among older people. This study explored the association of HGS with depression and cognitive impairment among community‐dwelling older adults in resource‐constrained setting of India. Method Data were drawn from the Longitudinal Ageing Study in India (LASI), and the analysis was conducted on 27,707 older adults aged 60 years and above. Outcome measures included depression (assessed by the Short Form Composite International Diagnostic Interview (CIDI‐SF) and the Center for Epidemiological Studies‐Depression (CES‐D) scales) and cognitive impairment. Descriptive statistics and mean scores of HGS were reported and multivariable linear regression analyses were conducted to test the research hypotheses of the study. Results Mean score of HGS was 24.33 (SD: 7.22) for males and 15.94 (SD: 5.14) for females. Mean age was 68.86 (SD: 7.19) and 68.40 (SD: 7.31) years among males and females respectively. Older participants who had weak HGS were significantly more likely to be depressed in CIDI‐SF scale (B: 0.06, CI: 0.01–0.13) and CES‐D scale (B: 0.02, CI: 0.01–0.03) in comparison to those who had strong HGS after adjusting for a large number of confounders. Older participants who had weak HGS were significantly more likely (B: 0.92, CI: 0.76–1.07) to have cognitive impairment compared to those who had strong HGS. Conclusion The findings highlight the independent association of HGS with major depression, depressive symptoms and cognitive impairment that have implications on promoting resistance‐training programs among aged population.

The Mediating Role of Cognitive Function in the Association between Grip Strength and Depression among Chinese middle-aged and elderly adults: A Cross-Sectional Study

“…Its simplicity, portability, and low cost make it an attractive tool for assessing individual health risks ([38]). Previous research into grip strength and depression has indicated that weak grip strength might be a risk factor for depression in middle-aged and elderly individuals [39][40]. These studies have suggested a doseresponse relationship between grip strength and depression risk, highlighting a negative correlation between grip strength and the risk of depression.…”

Examining factors contributing to the socioeconomic inequalities in handgrip strength among older adults in India: a decomposition analysis

“…Since standards based on high-income countries pose a considerable problem in properly assessing grip strength, the reference standards for phenotypically different Indian populations were used in the current study. Thus, the cut-off for weak HGS for males was 19.5 kg; for females, it was 12.5 kg, taken as the lowest 25th percentile or lowest quartile, validated in the Indian context 39 – 41 . Sensitivity analysis was conducted using a cut-off suggested by the Asian Working Group on Sarcopenia, with less than 28 kg for males and less than 18 kg for females 42 .…”

Sức Mạnh Cơ Tay Và Một Số Yếu Tố Liên Quan Ở Người Bệnh Parkinson Cao Tuổi

“…Sức mạnh cơ chi trên trung bình của nhóm người bệnh có suy giảm nhận thức thấp hơn có ý nghĩa thống kê so với nhóm người bệnh không bị suy giảm nhận thức (14,8 kg so với 21,7 kg). Có điểm tương đồng trong một nghiên cứu theo chiều dọc ở Ấn Độ, cũng thấy mối liên quan giữa suy giảm nhận thức với cơ lực tay, những người cao tuổi tham gia nghiên cứu có cơ lực tay yếu có khả năng bị suy giảm nhận thức cao hơn (B: 0,92, CI: 0,76-1,07) so với những người có cơ lực tay mạnh [10].…”