Relationship between Helicobacter pylori Infection and Parasitic Infection in Patients in Ilam

Kazemian, Hossein; Heidari, Hamid; Kardan-Yamchi, Jalil; Shavalipour, Aref; Ghafourian, Sobhan; Mohebi, Reza; Houri, Hamidreza; Sadeghifard, Nourkhoda

doi:10.18869/modares.iem.2.2.15

Cited by 7 publications

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of G. intestinalis (19.3%) was lower than that reported by Kazemian et al (2016) and Isaeva et al (2010) Ahmed et al (2018).…”

Section: Discussioncontrasting

confidence: 51%

“…Urease produced by H. pylori can transform the urea of stomach wall to ammonia resulting in the increment of gastric envi-Acidity of the stomach is considered an important barrier of the innate immune system that protect against invasion by pathogens, therefore the diminished acidity will give pathogens the opportunity to break this barrier and go across it invading the gastric mucosa (Kazemian et al, 2016). H. pylori infection shared intestinal Parasites in multiple clinical presentations as diarrhea, dysentery, vomiting, lack of appetite and abdominal distention (Ahmed et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Helicobacter Pylori Co-Infected With Common Intestinal Protozoa in Gastrointestinal Symptomatic Patients

Ghallab

Morsy

2020

Journal of the Egyptian Society of Parasitology

View full text Add to dashboard Cite

The zoonotic intestinal protozoan parasites and Helicobacter pylori) are worldwide distributed human pathogens. This study evaluated the co-infection between H. pylori and the commonest intestinal protozoan parasites. A total of 240 stool samples were collected over one year from patients attending outpatients' clinics of Kafrelsheikh University Hospitals, after verbal consent for participation. Samples were subjected to microscopic examination directly before and after formol ether concentration. Samples were examined using merthiolate iodine formalin (MIF) direct smears to detect G. intestinelis and permanent modified trichrome and modified acid-fast cold kinyoun's stained smears to detect E. histolytica/dispar and Cryptosporidium spp. respectively. Screening with immune-chromatographic test (ICT) detected H. pylori infection. The results showed that H. pylori were in 160/240 (66.7%). Univariate analysis showed significance association between H. pylori and protozoan causing diarrhea (P = 0.015). These protozoan parasites were with G. intestinalis ((P=0.002), E. histolytica/dispar (P= 0.041), Cryptosporidium parvum (P =0.018) and Blastocystis hominis (P= 0.040).

show abstract

“…The prevalence of G. intestinalis (19.3%) was lower than that reported by Kazemian et al (2016) and Isaeva et al (2010) Ahmed et al (2018).…”

Section: Discussioncontrasting

confidence: 51%

Section: Introductionmentioning

confidence: 99%

Helicobacter Pylori Co-Infected With Common Intestinal Protozoa in Gastrointestinal Symptomatic Patients

Ghallab

Morsy

2020

Journal of the Egyptian Society of Parasitology

View full text Add to dashboard Cite

show abstract

“…The results indicated that cagA was positive in 44.4% of patients with gastric pain symptoms. Moreover, clinical signs of abdominal pain were predominant in patients with H. pylori infection, which is similar to other studies performed in the same city [18][19][20] .…”

Section: Discussionsupporting

confidence: 89%

“…The percentage of vacA s2m2 genotype in this study was 32.9%, which is lower than those reported in other studies conducted in Australia (35%), Alaska (38%), and North Africa (57%) [23,30,34] . It should be noted that s1m1 and s2m2 genotypes have the highest and lowest cytotoxic activity, respectively [35][36][37][38] , and vacA s2m2 genotype has the lowest prevalence (0-57%) among all genotypes reported worldwide [20,26,30] .…”

Section: Discussionmentioning

confidence: 99%

Evaluating the Genetic Diversity of Helicobacter pylori Isolates in Patients Suffering from Gastritis

Mami

Khaleghnezhad²,

Mami³

et al. 2022

IEM

View full text Add to dashboard Cite

Backgrounds: Helicobacter pylori infections vary in severity and virulence in different populations for various reasons. There are different H. pylori strains with varying degrees of virulence. The genetic diversity of H. pylori strains in gastritis patients in different areas has not been well understood. This study aimed to evaluate the prevalence rate and different genotypes of H. pylori strains in clinical specimens of patients with gastritis in Ilam, Iran. Materials & Methods: Saliva and gastric biopsy samples were collected from 81 patients (55 males and 26 females in the age range of 20 to 90 years) referring to Ilam medical centers.After DNA extraction, the prevalence of H. pylori as well as vacA, cagA, and ureC genes was evaluated using PCR, and then each vacA-positive sample was further evaluated for m1m2 and s1s2 variants. Findings: The cagA and vacA genes were found in 27 (71%) and 36 (94.7%) H. pylori-positive samples, respectively. The cagA gene was detected in patients with gastric pain (44.4%) and anorexia (18.51%). Also, the results showed that the vacA s2m2 genotype and m2 allele were present in 32.9% of H. pylori isolates. Moreover, s2m2 and s1m2 genotypes were detected in 42.1 and 26.3% of vacA-positive samples, respectively. The lowest frequency was related to the m1 allele (17.18%). Conclusion:This study results indicate a plausible relationship between the presence of some genotypes of H. pylori and the progression of gastritis, suggesting these markers as promising biomarkers to predict the disease severity.

show abstract

“…Concurrent infection of H. pylori and intestinal parasites was reported in a number of studies [31,32,[49][50][51][52][53] . Under normal conditions, gastric juice creates an unfavorable medium for pathogenic microorganisms.…”

Section: Discussionmentioning

confidence: 99%

Stressing a tired host: Cryptosporidium species and Helicobacter pylori infections in diabetes mellitus patients with gastrointestinal manifestations

Abdel-Shafi¹,

Fadl²,

Elsayed³

et al. 2021

Parasitologists United Journal

View full text Add to dashboard Cite

show abstract

Relationship between Helicobacter pylori Infection and Parasitic Infection in Patients in Ilam

Cited by 7 publications

References 13 publications

Helicobacter Pylori Co-Infected With Common Intestinal Protozoa in Gastrointestinal Symptomatic Patients

Helicobacter Pylori Co-Infected With Common Intestinal Protozoa in Gastrointestinal Symptomatic Patients

Evaluating the Genetic Diversity of Helicobacter pylori Isolates in Patients Suffering from Gastritis

Stressing a tired host: Cryptosporidium species and Helicobacter pylori infections in diabetes mellitus patients with gastrointestinal manifestations

Contact Info

Product

Resources

About