Relationship between Helicobacter pylori infection and iron deficiency anemia in children: A review article

Abstract

Background: One of the greatest prevalent chronic illnesses, Helicobacter pylori (H. pylori), affects around 50% of people globally. Early infancy is when this virus is most often contracted, particularly in developing nations. The frequency of H. pylori varies greatly across nations; in underdeveloped nations, 50% of children are infected by the time they become 10 years old. The beginning of several Gastro intestinal tract pathologies, including active persistent gastritis, peptic ulcers, gastric carcinoma, extragastric symptoms, thrombocytopenic purpura, and anemia owing to inadequate iron reserves iron deficiency anemia (IDA), is discovered to be related with H. Pylori infections. A link between anemia and H. pylori infections is supported by a variety of data from epidemiological and clinical research.Objectives: To highlight connection between Helicobacter pylori infections and IDA in children, and to explore the mechanism of this association. Conclusion:Infection with Helicobacter pylori is substantially linked with iron deficiency anemia in children.

Severe Unexplained Iron Deficiency Anemia in Children: High Yield of Upper Gastrointestinal Endoscopy Regardless of Gastrointestinal Symptoms

“…According to these studies, approximately 50% of patients presenting with IDA were found to have H. pylori gastritis. [29][30][31] Studies that evaluated UGE in severe pediatric IDA are scarce, with rates of H. pylori gastritis ranging from 17-37%. 18,20,28 Our study yielded similar results, revealing that 36% of the children who underwent endoscopy were identified as positive for H. pylori.…”

“…Numerous studies have established a link between H. pylori gastritis and IDA in both adults and children. According to these studies, approximately 50% of patients presenting with IDA were found to have H. pylori gastritis 29–31 . Studies that evaluated UGE in severe pediatric IDA are scarce, with rates of H. pylori gastritis ranging from 17-37% 18,20,28 .…”

Possible Role of Helicobacter pylori in Ear Nose and Throat Diseases

“…1 H. pylori is assumed to cause many gastric diseases such as chronic and acute gastritis, gastric ulcers, lymphoma and adenocarcinoma. [2][3][4] In addition to its gastrointestinal effects, it can cause head and neck disorders, atherosclerosis, lung, hepato-biliary, hematological, and intestinal diseases. 5 H. pylori is primarily found in the stomach, and numerous studies have linked it to disorders of the upper airways.…”