Relationship Between Hypertension and Cognitive Function in an Elderly Population: A Population-Based Study in Rural Northern China

Abstract

The burden of cognitive impairment and dementia is particularly severe in low- and middle-income countries. Although hypertension is an important risk factor for cognitive impairment, the influence of different hypertension classification on cognitive impairment remains controversial. To explore the impact of hypertension and hypertension classification on cognitive function, this study was based on a low-income population aged over 60 years in northern China. This population-based, cross-sectional study was conducted from April 2014 to January 2015 in rural areas of Tianjin, China. A total of 1,171 participants aged ≥ 60 years were included. Participants were interviewed by professional researchers face-to-face, using the pre-designed questionnaire. Cognitive function was assessed using the Mini-mental State Examination (MMSE). Multivariate regression analysis was used to calculate the odds ratio (OR) value. There was a significant association between hypertension and cognitive impairment (OR, 1.415; 95% CI: 1.005–1.992; P = 0.047) and a significant positive association between stage 3 hypertension (OR, 1.734; 95% CI: 1.131–2.656; P = 0.012) and the prevalence of cognitive impairment. To prevent dementia, clinicians should consider the cognitive function and blood pressure control of low-income individuals aged over 60 years with hypertension in northern China, especially those with stage 3 hypertension. In addition, the inconsistent effects of blood pressure on different cognitive functions should also be considered; special attention should be paid to orientation and concentration.

Hubungan Kejadian Hipertensi dengan Fungsi Kognitif Lansia

“…Masalah itu terkait adanya penurunan daya ingan lanjut usia. Hasilstudi selaras studi sebelumnya (Bao et al, 2022) menyatakan terutama pada unsur arah, bahasa, perhatian dan perhitungan pada aspek-aspek tersebut skor pada pasien hipertensi berkurang drastis, karena jaringan otak yang berbeda memiliki kepekaan yang berbeda.…”

“…Berdasarkan hasil penelitian sebelumnya oleh (Bao et al, 2022) menunjukkan korelasi antara tekanan darah tinggi dan gangguan kognitif (p=0,047) dan korelasi (+) signifikan antara hipertensi stadium 3 (p=0,012). Ada beberapa penelitian lainnya juga yang dilakukan (Mutia, 2022) menunjukkan ada hubungan yang signifikan antara klasifikasi tekanan darah dan turunnya fungsi kognitif lansia (p-value 0,009) dibuktikan dengan hasil penelitian dengan 46 orang subjek, penderita hypertension tingkat 1 1 sejumlah 28 lansia (60,9 %) dan penderita hypertension tingkat2 sejumlah 18 lansia (39,1%) dan dibuktikan dan nilai OR=5,762 berarti penderita hypertension berisiko terjadi penurunan fungsi kognitif daripada yang tidak.…”

Edukasi Mengenai Gangguan Kognitif Pada Pasien Hipertensi di Poli Neurologi Rumah Sakit Universitas Mataram

“…Hipertensi, juga dikenal sebagai tekanan darah tinggi, merupakan masalah kesehatan yang umum terjadi di seluruh dunia dan dapat menimbulkan dampak yang serius pada fungsi kognitif individu. Gangguan kognitif pada pasien hipertensi meliputi penurunan daya ingat, penurunan fungsi eksekutif, dan gangguan pengolahan informasi, yang semuanya berpotensi mempengaruhi kualitas hidup mereka (Bao et al, 2022).…”