Relationship between indocyanine green retention test, decompensation and survival in patients with Child‐Pugh A cirrhosis and portal hypertension

Abstract

ICG-r15 appears to be strictly related to liver decompensation, longitudinally confirming the preliminary findings of its correlation with PH among patients with compensated cirrhosis, and can be used for patient prognostication.

Evolving strategies for liver fibrosis staging: The non-invasive assessment

“…In patients with compensated cirrhosis, this test correlated to the degree of portal hypertension and oesophageal varices. ICG-r15 appears to be accurately related to liver decompensation, confirming the preliminary findings of its association with portal hypertension in compensated patients, and can be used for patient prognostication[36]. Li et al[37] assessed the hepatic functional reserve in patients with HCC through the use of magnetic resonance elastography (MRE).…”

“…Recently, the indocyanine green retention test at 15 min (ICG-r15; routinely used for evaluating hepatic function in patients undergoing hepatic surgery for liver tumour) has been investigated and has been proposed and clinically evaluated as a prognostic marker in patients with advanced cirrhosis[36]. In patients with compensated cirrhosis, this test correlated to the degree of portal hypertension and oesophageal varices.…”

Serum Wisteria floribunda agglutinin‐positive Mac‐2‐binding protein evaluates liver function and predicts prognosis in liver cirrhosis

“…Compensated LC is the asymptomatic stage of the disease which is characterized by good life quality and relatively long life expectancy, while the natural history becomes more rapid and progressive with the occurrence of clinical decompensation . Hence, determining a predictor for disease progression is of clinical significance for LC patients.…”

Indocyanine green retention test in cirrhosis and portal hypertension: Accuracy and relation to severity of disease

“…Significant relations of the ICG‐r15 test to Child or MELD scores have previously been studied . However, with respect to survival, Stauber et al .…”