Relationship between Inflammatory Parameters and Cardiovascular and Lifestyle Factors in the Mugello Study Oldest Old

Lova, Raffaele Molino; Vassalle, Cristina; Masini, Elisabetta; Ry, Silvia Del; Cabiati, Manuela; Pasquini, Guido; Macchi, Claudio

doi:10.2217/bmm-2017-0441

Cited by 1 publication

(1 citation statement)

References 40 publications

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“…Main comorbidities, also considered as dichotomous variables, were determined by medical history and examination, and medical records information (Molino-Lova et al, 2013). Hemoglobin concentration (g/dL) was analyzed using the hematology analyzer Sysmex XT-1800 (Sysmex, Inc., Mundelein, IL), and high-sensitivity C-reactive protein (CRP) was measured in duplicate using an enzyme-linked immunosorbent assay (ELISA) and colorimetric competitive immunoassay that used purified protein and polyclonal anti-CRP antibodies (Molino-Lova et al, 2018). BMI was calculated, as well as data on medication history were collected with regard to type of drugs, treatment duration, and possible reported side effects.…”

Section: Methodsmentioning

confidence: 99%

Independent Functioning in Nonagenarians Living in a Rural Italian Community: The Mugello Study

et al. 2019

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Nonagenarians are a fast-growing population deserving specific research. We explored the prevalence and characteristics of functionally independent nonagenarians from a rural community-dwelling Italian population. Data were collected in the Mugello Study; 475 persons aged ≥90 years (median age, 92) underwent a home-based clinical and functional assessment, including psychosocial, clinical, functional, and lifestyle history and status and physical and instrumental examinations. Sixty-eight (15%) persons reported no need for help in basic and instrumental daily living activities. Among variables significantly associated with independent functionality after age- and gender-adjusted cross-sectional analysis, lower body mass index (BMI; p = .034) and depressive symptoms ( p = .028), higher current physical activity ( p < .001), better cognitive status ( p = .033), and lower medication intake ( p = .048) were associated with reporting no disability in the logistic regression analysis. Disability was mainly associated with current lifestyle-related potentially modifiable factors. Thus, lifestyle-oriented multidimensional interventions, should be developed and evaluated for their potential effects on functionality, even in the oldest old.

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Section: Methodsmentioning

confidence: 99%

Independent Functioning in Nonagenarians Living in a Rural Italian Community: The Mugello Study

et al. 2019

View full text Add to dashboard Cite

show abstract

Relationship between Inflammatory Parameters and Cardiovascular and Lifestyle Factors in the Mugello Study Oldest Old

Abstract: Several inflammatory parameters remain associated with adverse lifestyle and cardiovascular risk factors even among nonagenarians.

Cited by 1 publication

References 40 publications

Independent Functioning in Nonagenarians Living in a Rural Italian Community: The Mugello Study

Independent Functioning in Nonagenarians Living in a Rural Italian Community: The Mugello Study

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