Relationship between Magnesium Intake and Chronic Pain in U.S. Adults

Tarleton, Emily K.; Kennedy, Amanda G.; Rose, Gail L.; Littenberg, Benjamin

doi:10.3390/nu12072104

Cited by 12 publications

(6 citation statements)

References 34 publications

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“…Pain severity was also positively associated with a high fat and sugar intake [125] and a low fruit and fiber intake [126]. There is also evidence that a low intake of magnesium and folic acid contributes to chronic musculoskeletal pain [127], whereas a high magnesium intake confers protective effects [128].…”

Section: Musculoskeletal Painmentioning

confidence: 99%

Lifestyle Adjustments in Long-COVID Management: Potential Benefits of Plant-Based Diets

Storz

2021

Curr Nutr Rep

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Purpose of Review The SARS-CoV-2-pandemic has caused mortality and morbidity at an unprecedented global scale. Many patients infected with SARS-CoV-2 continue to experience symptoms after the acute phase of infection and report fatigue, sleep difficulties, anxiety, and depression as well as arthralgia and muscle weakness. Summarized under the umbrella term “long-COVID,” these symptoms may last weeks to months and impose a substantial burden on affected individuals. Dietary approaches to tackle these complications have received comparably little attention. Although plant-based diets in particular were shown to exert benefits on underlying conditions linked to poor COVID-19 outcomes, their role with regard to COVID-19 sequelae is yet largely unknown. Thus, this review sought to investigate whether a plant-based diet could reduce the burden of long-COVID. Recent Findings The number of clinical trials investigating the role of plant-based nutrition in COVID-19 prevention and management is currently limited. Yet, there is evidence from pre-pandemic observational and clinical studies that a plant-based diet may be of general benefit with regard to several clinical conditions that can also be found in individuals with COVID-19. These include anxiety, depression, sleep disorders, and musculoskeletal pain. Adoption of a plant-based diet leads to a reduced intake in pro-inflammatory mediators and could be one accessible strategy to tackle long-COVID associated prolonged systemic inflammation. Summary Plant-based diets may be of general benefit with regard to some of the most commonly found COVID-19 sequelae. Additional trials investigating which plant-based eating patterns confer the greatest benefit in the battle against long-COVID are urgently warranted.

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Section: Musculoskeletal Painmentioning

confidence: 99%

Lifestyle Adjustments in Long-COVID Management: Potential Benefits of Plant-Based Diets

Storz

2021

Curr Nutr Rep

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“…Interestingly, although the intake of vitamin D was not statistically different, total intake of was very low, particularly given the ability of vitamin D to reduce inflammation [ 34 ]. Furthermore, green leafy vegetables are high in magnesium and potassium, where dietary magnesium can help muscle function and may improve MPs [ 35 ]. In line with this study, many previous studies found a strength association between dietary approach to stop hypertension (DASH) diet and improving body composition (reducing body fat and increasing muscle strength) and relieving pain [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

The Association Between Dietary Energy Density and Musculoskeletal Pain in Adult Men and Women

et al. 2022

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Musculoskeletal pains (MPs), defined as persistent or recurrent pain, is a complex health problem. High overall calorie and fat intake have been related to obesity and MPs. Dietary energy density (DED), defined as energy content of food and beverages (in kcal) per unit total weight, has been associated with chronic muscle, cartilage, bone damage and pain. Thus, the purpose of this study is to investigate the association between DED and MPs in adult men and women. A total of 175 men and women (> 18 years) with MP participated in the study. A validated short form physical activity (PA) questionnaire, demographic, and McGill Pain Questionnaire were used. Anthropometric measurements were evaluated via standard protocols. Furthermore, a seven-day 24-hour recall of diet was used to determine the dietary intake. Total DED was calculated and divided into quartiles. Linear regression was used to discern the association between DED and MPs in adults. Participants assigned in the highest category of DED were characterized by lower intake of potassium, magnesium, vitamin C, folate, and fiber. However, results showed displayed higher intake of sodium, vitamin E, vitamin B3, fat, protein, cholesterol, saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids (p < 0.001). Finally, after adjustment for confounders such as age, gender, PA, body mass index, waist circumference, education, job, marital status, history of some chronic diseases and vitamin C supplementation, a significant positive association was detected between DED and pain intensity. There was no significant association between DED and pain frequency in all models.

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“…In addition, a greater intake of sodium can increase pain (Salgado et al., 2015 ). Finally, foods rich in acid‐producing properties are usually low in magnesium; this nutrient can help to eliminate chronic pain due to prolonged opening of calcium channels and activation of N‐methyl‐D‐aspartate (NMDA) receptors, which can remain open in the absence of magnesium (Tarleton et al., 2020 ).…”

Section: Discussionmentioning

confidence: 99%

The relationship between dietary acid load and intensity of musculoskeletal pain condition: A population‐based study

Bahrampour

Clark

2022

Food Science & Nutrition

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Pain is a globally prevalent problem, and a comprehension of its pathophysiology is important with respect to patient's health. Musculoskeletal pain conditions (MPs) may be associated with physical, lifestyle, and nutrition status, while dietary acid load (DAL) may be inversely associated with musculoskeletal health in adults. This cross‐sectional study consisted of 175 adults experiencing pain. Anthropometric measurements, physical activity (PA), and pain intensity were assessed via specific questionnaires. Dietary data were collected using a 7‐day 24‐h recall. Foods and beverages were analyzed with Nutritionist IV software for extracting the total energy and nutrients. Net endogenous acid production (NEAP) and potential renal acid load (PRAL) were evaluated for assessing the DAL. Linear regression and Spearman correlation were used to investigate the association of exposure and input variables. Linear regression showed a positive relationship between PRAL and NEAP and pain intensity in the crude model. This significant positive relationship remained after adjusting for all confounders. A lower consumption of potassium, magnesium, vitamin B9 and C, and fiber was seen in the following quartiles of PRAL and NEAP. In addition, MPs intensity and PRAL and NEAP had a weak, positive correlation. This study suggests that a higher DAL may be associated with MPs. However, further research is needed.

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Relationship between Magnesium Intake and Chronic Pain in U.S. Adults

Cited by 12 publications

References 34 publications

Lifestyle Adjustments in Long-COVID Management: Potential Benefits of Plant-Based Diets

Lifestyle Adjustments in Long-COVID Management: Potential Benefits of Plant-Based Diets

The Association Between Dietary Energy Density and Musculoskeletal Pain in Adult Men and Women

The relationship between dietary acid load and intensity of musculoskeletal pain condition: A population‐based study

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