ObjectiveTo determine levels of moral distress in a pediatric unit caring for patients with tracheostomy/ventilator dependence.HypothesisMoral distress will be significant in a dedicated pediatric trach/vent unit.MethodsThe Moral Distress Survey‐Revised (MDS‐R) is a 21‐question survey measuring moral distress in pediatrics. The MDS‐R was anonymously distributed to medical degree/doctor of osteopathy (MD/DOs), advanced practice practitioners (APPs), registered nurses (RNs), and respiratory therapists (RTs) in a unit caring for tracheostomy/ventilator dependent patients. Descriptive statistics, bivariate and multivariate analysis were performed.ResultsResponse rate was 48% (61/127). Mean MDS‐R score was 83 (range 43–119), which is comparable to reported levels in the pediatric intensive care unit (ICU). APPs had the highest median rate of moral distress (112, interquartile range [IQR], 72–138), while MD/DOs had the lowest median score (49, IQR, 43–77). RNs and RTs had MDS‐R scores between these two groups (medians of 91 and 84, respectively).ConclusionsMoral distress levels in a unit caring for long term tracheostomy and ventilator dependent patients are high, comparable to levels in pediatric ICUs. APPs. APPs had higher levels of distress compared to other groups. This may be attributable to the constant stressors of being the primary provider for complex patients, especially in a high‐volume inpatient setting.