2021
DOI: 10.24996/ijs.2021.62.3.8
|View full text |Cite
|
Sign up to set email alerts
|

Relationship Between Orexin-A and Insulin Resistance in Patients with Type 2 Diabetes Mellitus

Abstract: Background: Orexin-A is an orexigenic hormone that plays an important role in the metabolism of blood glucose, insulin, and insulin resistance (IR). The pathogenesis of type 2 diabetes mellitus (T2DM) is related to the abnormality in insulin and IR. However, no sufficient studies to date have clearly shown the association of orexin-A with biochemical parameters related to T2DM. Objectives: The aim of this study was to determine the relation of orexin-A with IR and how they associate with physiological ch… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
2
1

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(1 citation statement)
references
References 22 publications
0
1
0
Order By: Relevance
“…Leptin is an adipokine that is secreted from adipose tissue and transported to the brain through blood brain barrier by leptin transporters called obesity receptors which stimulate the brain to reduce food intake, appetite body and regulate energy homeostasis.Leptin increases in obese persons [14].Also leptin receptor OBR expression increases to translocate the leptin to the brain to inform the brain about the status of body fat stores and induce anorexia that functions as an afferent signal in a negative feedback loop which maintains homeostatic control of adipose tissue mass [15].…”
Section: Resultsmentioning
confidence: 99%
“…Leptin is an adipokine that is secreted from adipose tissue and transported to the brain through blood brain barrier by leptin transporters called obesity receptors which stimulate the brain to reduce food intake, appetite body and regulate energy homeostasis.Leptin increases in obese persons [14].Also leptin receptor OBR expression increases to translocate the leptin to the brain to inform the brain about the status of body fat stores and induce anorexia that functions as an afferent signal in a negative feedback loop which maintains homeostatic control of adipose tissue mass [15].…”
Section: Resultsmentioning
confidence: 99%