Relationship Between Physical Performance and Mild Cognitive Impairment in Chinese Community-Dwelling Older Adults

Abstract

This study aimed to examine the relationship between physical performance and mild cognitive impairment (MCI) in Chinese older adults. Methods: The sample comprised 956 relatively healthy and aged ≥65 years old Chinese community-dwelling participants (mean age, 72.56 ± 5.43 years; 56.8% female), which did not include those with dementia, severe cognitive impairment, mental illness etc. The Mini-Mental State Examination (MMSE) and the Instrumental Activities of Daily Living (IADL) scale were used for the initial classification of patients with MCI. Physical performance was measured via hand grip, Timed Up and Go Test (TUGT), and 4-m walking speed. Results: The physical performance (grip strength, TUGT, and 4-m walking speed) correlated with MCI. The grip strength [odds ratio (OR) = 0.96, 95% confidence interval (CI) = 0.93-0.99] and 4-m walking speed (OR = 0.25, 95% CI = 0.10-0.64) correlated negatively with MCI, while TUGT (OR = 1.08, 95% CI = 1.03-1.13) and MCI correlated positively. Conclusion: The physical performance (grip strength, TUGT, and 4-m walking speed) correlated with MCI. Further analysis showed that the grip strength was associated with overall cognition, time orientation, recall, and language, while TUGT and 4-m walking speed were associated with overall cognition and various cognitive domains, except recall.

Association Between Physical Performance and Cognitive Function in Chinese Community-Dwelling Older Adults: Serial Mediation of Malnutrition and Depression

“…2 , 3 In our previous work, we found that grip strength was associated with overall cognition, time orientation, recall, and language, while the Timed-up to go test and 4-m walking speed were associated with overall cognition and various cognitive domains, except recall. 4 These results have not been fully supported by other reported studies. 5 , 6 Thus, the role of confounders and the underlying mechanism remain incompletely defined, necessitating further studies.…”

“…Our research population included residents from Chongming, Shanghai, China, who had joined China's national free physical examination program between March 2019 and September 2020. Individuals were included as following criteria: 4 (1) Older adults people ≥65 years old; (2) Have lived in the community for at least one year; (3) Willing to participate in this study. Exclusion criteria: 4 (1) General cognitive function was assessed using the Chinese version of the Matisse Dementia Rating Scale (CDRS), excluding participants who already had severe cognitive impairment and dementia or other neurodegenerative diseases; (2) those who could not take care of themselves and the instrumental activities of daily living scale were more than or equal to three items that could not be completed and could not walk independently; (3) people with hearing impairment, visual impairment and communication difficulties; (4) those who took sedatives in the last one or two months; (5) unable to perform the physical performance test.…”

“… 24 IADL scores ≥6 indicates normal daily activity ability which includes 8 items, the score ranges from 0 to 8 points, with the higher scores indicating better daily activity ability. 4 , 25 …”

“…In our previous study, we found greater grip strength and faster walking speed were the protective factors for MCI. 4 Besides, Kuan et al 2 suggested that regardless of musculoskeletal function, the early stage of MCI, will have adverse effects on balance function.…”

Obesity, Even in the Metabolically Healthy, Increases the Risk of Poor Physical Performance: A Cross-Sectional Study of Older People in a Chinese Community

“…15,19 Covariates Face-to-face epidemiological questionnaire interviews were performed by trained interviewers to collect information on sociodemographic, behavioral characteristics, and medical conditions as our previous study. 20,21 Sociodemographic variables included sex, age, marital status, living situation, education level, and occupation. Behavioral characteristics included smoking (never, former, or current smoker), and drinking habits (never, former, occasional, or daily drinker), and physical activity situation.…”