Relationship Between Polyethylene Wear and Osteolysis in Hips Witha Second-Generation Porous-Coated Cementless Cup After Seven Years of Follow-Up

Orishimo, Karl F.; Claus, Alexandra M.; Sychterz, Christi J.; Engh, Charles A.

doi:10.2106/00004623-200306000-00018

Cited by 170 publications

(93 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The success of efforts to increase the crosslinking in liners to improve wear characteristics is supported by studies such as ours. The osteolytic debris threshold for polyethylene wear has been estimated at 0.1 to 0.2 mm/year [8,36]. In our study, none of the HXLPE liners had wear above 0.1 mm/year, whereas two of the UHMWPE liners did.…”

Section: Discussionmentioning

confidence: 41%

The John Charnley Award: Highly Crosslinked Polyethylene in Total Hip Arthroplasty Decreases Long-term Wear: A Double-blind Randomized Trial

Glyn-Jones

Thomas

Roberts

et al. 2015

Clinical Orthopaedics &Amp; Related Research

136

View full text Add to dashboard Cite

Background The use of highly crosslinked polyethylene (HXLPE) is now commonplace for total hip arthroplasty. Hip simulator studies and short-term in vivo measurements suggest that the wear rate of some types of HXLPE is significantly less than conventional ultrahigh-molecularweight polyethylene (UHMWPE). However, there are few long-term data to support its use. Questions/purposes The aim of this study was to measure the long-term steady-state wear of HXLPE compared with UHMWPE liners in a prospective, double-blind, randomized controlled trial using radiostereometric analysis. Methods Fifty-four patients were randomized to receive hip arthroplasties with either UHMWPE liners or HXLPE liners. Complete followup was available on 39 of these patients (72%). All patients received the same cemented stem and an uncemented acetabular component. Threedimensional penetration of the head into the socket was determined at 10 years using a radiostereometric analysis system, which has an in vivo accuracy of \ 0.1 mm. Oxford Hip Scores were compared between the groups. Results At 10 years there was significantly less wear of HXLPE (0.003 mm/year; 95% confidence interval [CI], ± 0.010; SD 0.023; range, À0.057 to 0.074) compared with UHMWPE (0.030 mm/year; 95% CI, ± 0.012; p \ 0.001; SD 0.0.27; range, À0.001 to 0.164). The volumetric penetration from 1 to 10 years for the UHMWPE group was 98 mm 3 (95% CI, ± 46 mm 3 ; SD 102 mm 3

show abstract

Section: Discussionmentioning

confidence: 41%

The John Charnley Award: Highly Crosslinked Polyethylene in Total Hip Arthroplasty Decreases Long-term Wear: A Double-blind Randomized Trial

Glyn-Jones

Thomas

Roberts

et al. 2015

Clinical Orthopaedics &Amp; Related Research

136

View full text Add to dashboard Cite

show abstract

“…A direct relationship between polyethylene wear and the prevalence of periprosthetic osteolysis and component loosening has been confirmed [7,9,22,24].…”

Section: Introductionmentioning

confidence: 83%

Similar Wear in Total Hip Arthroplasties with Metallic or Zirconia Femoral Heads

Cohn

Valle

Peterson

2008

HSS Journal®: The Musculoskeletal Journal of Hospital for Speci

View full text Add to dashboard Cite

Ceramic femoral heads have been used in an attempt at reducing polyethylene wear of total hip arthroplasties. Clinical results with zirconia femoral heads have been mixed. This study was undertaken to compare the polyethylene wear and incidence of periprosthetic osteolysis in total hip replacements performed using a 28-mm zirconia versus a 28-mm cobalt chromium femoral head. Thirty-five hips with a 28-mm cobalt chromium head and 68 hips with a 28-mm zirconia head were evaluated after a minimum follow-up of 2 years (average, 4.0 years; range, 2.0 to 9.1 years). A monoblock acetabular component was used in all patients. Polyethylene wear was measured in serial radiographs from 58 of the hips utilizing a computerassisted vector wear technique. Periacetabular osteolysis developed in three patients (two with a zirconia head and one with a cobalt chromium head). The total wear and the annual wear rate were 0.48 mm and 0.11 mm/year for the cobalt chromium heads and 0.53 mm and 0.14 mm/year for the zirconia heads, respectively. We found no benefit with respect to the rate of polyethylene wear or incidence of osteolysis with the use of zirconia femoral heads.

show abstract

“…The osteolytic effect of wear debris depends not only on particle size and shape but also mainly on the particle volume released into the surrounding tissue [14,24]. Numerous authors have reported, with standard 28-mm heads, linear wear rates greater than 0.2 mm per year always produce wear particle-induced osteolysis, whereas this mostly is absent at annual wear rates less than 0.05 to 0.1 mm per year [1,4,10,11,20,29,32,34,35]. Therefore, increasing wear resistance of the PE for acetabular cups has been a major target.…”

Section: Introductionmentioning

confidence: 99%

Cross-linked Compared with Historical Polyethylene in THA: An 8-year Clinical Study

Geerdink

Grimm

Vencken

et al. 2008

Clin Orthop Relat Res

View full text Add to dashboard Cite

Wear particle-induced osteolysis is a major cause of aseptic loosening in THA. Increasing wear resistance of polyethylene (PE) occurs by increasing the crosslink density and early reports document low wear rates with such implants. To confirm longer-term reductions in wear we compared cross-linked polyethylene (irradiation in nitrogen, annealing) with historical polyethylene (irradiation in air) in a prospective, randomized clinical study involving 48 patients who underwent THAs with a minimum followup of 7 years (mean, 8 years; range, 7-9 years). The insert material was the only variable. The Harris hip score, radiographic signs of osteolysis, and polyethylene wear were recorded annually. Twenty-three historical and 17 moderately cross-linked polyethylene inserts were analyzed (five patients died, three were lost to followup). At 8 years, the wear rate was lower for crosslinked polyethylene (0.088 ± 0.03 mm/year) than for the historical polyethylene (0.142 ± 0.07 mm/year). This reduction (38%) did not diminish with time (33% at 5 years). Acetabular cyst formation was less frequent (39% versus 12%), affected fewer DeLee and Charnley zones (17% versus 4%), and was less severe for the cross-linked polyethylene. The only revision was for an aseptically loose cup in the historical polyethylene group. Moderately cross-linked polyethylene maintained its wear advantage with time and produced less osteolysis, showing no signs of aging at mid-term followup.

show abstract

Relationship Between Polyethylene Wear and Osteolysis in Hips Witha Second-Generation Porous-Coated Cementless Cup After Seven Years of Follow-Up

Cited by 170 publications

References 12 publications

The John Charnley Award: Highly Crosslinked Polyethylene in Total Hip Arthroplasty Decreases Long-term Wear: A Double-blind Randomized Trial

The John Charnley Award: Highly Crosslinked Polyethylene in Total Hip Arthroplasty Decreases Long-term Wear: A Double-blind Randomized Trial

Similar Wear in Total Hip Arthroplasties with Metallic or Zirconia Femoral Heads

Cross-linked Compared with Historical Polyethylene in THA: An 8-year Clinical Study

Contact Info

Product

Resources

About