Relationship between quality of life and social integration among patients with schizophrenia attending a Nigerian tertiary hospital

Ogundare, Temitope; Onifade, Peter Olutunde; Ogundapo, Deji; Ghebrehiwet, Senait; Borba, Christina P.C.; Henderson, David C.

doi:10.1007/s11136-021-02764-x

Cited by 4 publications

(2 citation statements)

References 57 publications

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“…6 25 In contrast, findings from Portugal 27 and Nigeria indicated that the mean value for each domain of HRQoL was high as compared with this study, and the lowest mean score was in the physical domain. 28 This discrepancy might be due to differences in the sociodemographic characteristics of respondents, differences in the clinical set-up, and inclusion and exclusion criteria. For example, the study in Nigeria excluded respondents older than 64 and those with a physical comorbid disease.…”

Section: Discussionmentioning

confidence: 99%

Health-related quality of life and associated factors among patients with schizophrenia at comprehensive specialised hospitals in the Northwest Ethiopia: a multicentre cross-sectional study

Tamene,

Sema,

Mihiretie

et al. 2023

BMJ Open

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ObjectivesThe aim of this study was to assess the health-related quality of life (HRQoL) and associated factors among patients with schizophrenia at comprehensive specialised hospitals in Northwest Ethiopia.Design and settingA cross-sectional study was conducted among 422 patients with schizophrenia who were followed at comprehensive specialised hospitals in Northwest Ethiopia from 1 June to 30 August 2022.ParticipantsAll adult patients with schizophrenia who had regular follow-up in the outpatient departments of the selected hospitals were study participants.Main outcome measuresThe main outcome of this study was HRQoL which was measured using the WHO Quality of Life Scale–Bref Version. Data entry and analysis were done using Epi-data version 4.6.1 and SPSS version 24, respectively. Linear regression was used to assess the association between quality of life and independent variables. Variables with a p value <0.05 at a 95% CI were considered statistically significant.ResultsThe mean score of the overall Quality of Life Scale–Brief Version was 22.42±3.60. No formal education (ß=−1.53; 95% CI: −2.80 to –0.27), duration of treatment (ß = –3.08; 95% CI: −4.71 to –1.45), comorbidity (ß=−1.14; 95% CI: −1.99 to –0.29), substance use (ß=−0.89; 95% CI: −1.56 to –0.23), extrapyramidal side effects (ß=−2.02; 95% CI: −2.90 to –1.14), non-adherence (ß=−0.83; 95% CI: −1.44 to –0.23), and antipsychotic polypharmacy (ß=−1.77; CI: −2.57 to –0.96) were negatively associated with quality of life.Conclusion and recommendationIn this study, the social domain was recorded as having the lowest mean score, which may indicate that patients with schizophrenia could need better psychosocial support. Patients with a longer duration of treatment, who had comorbid illnesses, were substance users, developed EPS, were non-adherent to medications and were on antipsychotic polypharmacy, needs critical follow-up to improve HRQoL.

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Section: Discussionmentioning

confidence: 99%

Health-related quality of life and associated factors among patients with schizophrenia at comprehensive specialised hospitals in the Northwest Ethiopia: a multicentre cross-sectional study

Tamene,

Sema,

Mihiretie

et al. 2023

BMJ Open

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“…In addition, stigmatization can hinder early treatment and recovery of people with mental illness, leading to prolonged recovery time, which further reduces QOL [34][35][36]. Second, stigma can limit the ability of PWS to express their distress and seek help, thereby impairing their social interactions and increasing their risk of depression [37,38]. The issue of stigma was also found in a longitudinal study to significantly affect PWS, who feared disclosure of their illness, and the results of that study suggested that the more stigmatized the patient was, the more depressed he or she felt [39].…”

Section: Introductionmentioning

confidence: 99%

Depression severity mediates stigma and quality of life in clinically stable people with schizophrenia in rural China

Zheng,

Wang,

Zhang

et al. 2023

BMC Psychiatry

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Background Depressive symptoms associated with schizophrenia are closely related to stigma and quality of life(QOL). There is, however, no thorough research on the connection between the three. This study sought to investigate the possible factors influencing depressive symptoms in people with schizophrenia (PWS) in rural Chaohu, China, and to further explore the role of depression severity in stigma and lifestyle quality. Methods Eight hundred twenty-one schizophrenia patients accomplished the entire scale, including the 9-item Patient Health Questionnaire (PHQ-9), the Social Impact Scale (SIS), and the World Health Organization on Quality of Life Brief Scale(WHOQOL—BREF). A straightforward mediation model was employed to determine if the intensity of the depression could act as a mediator between stigma and QOL. Results Two hundred seventy-nine schizophrenia patients (34%) had depressive symptoms (PHQ ≥ 10), and 542 patients (66%) did not (PHQ < 10). Logistic regression showed that marital status, job status, physical exercise, standard of living, and stigma contributed to the depressed symptoms of schizophrenia. Depression severity partially mediated the effect between stigma and QOL, with a mediating effect of 48.3%. Conclusions This study discovered a significant incidence of depressed symptoms associated with schizophrenia, with depression severity serving as a mediator variable connecting stigma and QOL and partially moderating the association.

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The role of self-efficacy and self-esteem in mediating positive associations between functional social support and psychological wellbeing in people with a mental health diagnosis

Rippon

Shepherd

Wakefield³

et al. 2022

Journal of Mental Health

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Relationship between quality of life and social integration among patients with schizophrenia attending a Nigerian tertiary hospital

Cited by 4 publications

References 57 publications

Health-related quality of life and associated factors among patients with schizophrenia at comprehensive specialised hospitals in the Northwest Ethiopia: a multicentre cross-sectional study

Health-related quality of life and associated factors among patients with schizophrenia at comprehensive specialised hospitals in the Northwest Ethiopia: a multicentre cross-sectional study

Depression severity mediates stigma and quality of life in clinically stable people with schizophrenia in rural China

The role of self-efficacy and self-esteem in mediating positive associations between functional social support and psychological wellbeing in people with a mental health diagnosis

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