Relationship between Secondary Metabolites, Antiradical Activities, and Colour Characteristics of Cochlospermum Tinctorium A. Rich. (Bixaceae) Root

Abstract

Cochlospermum tinctorium A. Rich. (Bixaceae) is a widespread herbaceous plant in the African sahelian and soudanian zones. Its root is used as food and medicinal plant. Studies of secondary metabolites, functional activities and trichromatic parameters were realized according to standard methods of laboratory. At a threshold of α = 0.05, significant correlations (p < 0.05) were found between secondary metabolites contents and functional activities such as radical scavenging activity of antioxidant component or hydroxyl radical scavenging activity. The value of DPPHH was 95.56 ± 0.94% for CT inner Matrix with variation of 0.12% for CT Soaked inner Matrix and 1.63% for CT Peeler. But HSRA was 37.14 ± 5.71 for CT inner Matrix with variation of-38.46% for CT Soaked inner Matrix and-71.79% for CT Peeler. Cochlospermum tinctorium root has exhibited efficiency to heal many diseases thanks to multiple bioactive compounds. In addition, the colour of powders depended upon chemical compounds. Finally, Cochlospermum tinctorium root was found to neutralize organic radicals and reactive oxygen species.

Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review

“…The roots decoction or infusion are taken with other herbs for the treatment of malaria [5], urethral discharges, orchitis, and fever [13]. In addition, the roots of C. tinctorium are used in traditional medicine for the treatment of infectious diseases [17], diabetes mellitus [18], epilepsy [19], pain and inflammation [20], conjunctivitis, leprosy, and testicular inflammation [8].…”

“…The rhizomes of C. tinctorium are used as a decoction for the treatment of rickets, stomach pain, helminthiasis, beriberi [21], fever, hepatitis, abdominal pain, and bilharzia [18]. The leaves of C. tinctorium are used for the management of diarrhea [22], abscess, and boils [8], while the flowers are used against constipation [8].…”

“…Etuk et al also reported the presence of alkaloids, tannins, cardiac glycosides, saponins, flavonoids, triterpenes, cyanogenic glycosides, and volatile oils in the aqueous root extract of C. tinctorium [28]. Ndouyang and co-workers reported the presence of secondary metabolites such as tannins (total, hydrolysable, and condensed), phytates, oxalates, carotenoids, cyanides, alkaloids, flavonoids, and phenols in the root of C. tinctorium [18].…”

“…The antioxidant activity of the aqueous root extract of C. tinctorium was evaluated using DPPH radical scavenging activity, hydroxyl radical scavenging activity, and ferric iron-reducing activity [18]. The extract produced significant antioxidant activity against DPPH radical which could be related to the presence of soluble oxalates and phytates in the plant [18].…”

“…The antioxidant activity of the aqueous root extract of C. tinctorium was evaluated using DPPH radical scavenging activity, hydroxyl radical scavenging activity, and ferric iron-reducing activity [18]. The extract produced significant antioxidant activity against DPPH radical which could be related to the presence of soluble oxalates and phytates in the plant [18]. The extract also produced remarkable hydroxyl radical scavenging activity possibly due to the presence of phenolic compounds such as hydrolysable tannins, flavonoids, alkaloids, and carotenoids [18].…”