Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries

Stubbs, Brendon; Vancampfort, Davy; Firth, Joseph; Schuch, Felipe Barreto; Hallgren, Mats; Smıth, Lee; Gardner, Benjamin; Kahl, Kai G.; Veronese, Nicola; Solmi, Marco; Carvalho, André F.; Koyanagi, Ai

doi:10.1016/j.jad.2017.12.104

Cited by 123 publications

(96 citation statements)

References 70 publications

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“…Outcome expectations (impact of sitting), self‐efficacy, and perceived social support were not associated with SB in the study on Saudi working women . The presence of anxiety symptoms or depression was positively associated with total SB in two large multi‐country studies . The study by Koyanagi et al that used the same sample as in the studies above reported positive associations for low energy and negative affect with SB.…”

Section: Resultsmentioning

confidence: 68%

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Correlates of sedentary behaviour in Asian adults: A systematic review

et al. 2020

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Summary The objective of this study is to systematically review the evidence on correlates of sedentary behaviour (SB) among Asian adults. We searched for studies that examined individual, environmental, and political/cultural correlates of total and domain‐specific SB (transport, occupation, leisure, and screen time) in Asian adults published from 2000 onwards in nine scientific databases. Two reviewers independently screened identified references. Following quality assessment of included studies, we performed narrative synthesis that considered differences based on SB measurements, regions, and population characteristics (PROSPERO: CRD42018095268). We identified 13 249 papers of which we included 49, from four regions and 12 countries. Researchers conducted cross‐sectional analyses and most relied on SB self‐report for SB measurement. Of the 118 correlates studied, the following associations were consistent: higher age, living in an urban area (East Asia), and lower mental health with higher total SB; higher education with higher total and occupational SB; higher income with higher leisure‐time SB; higher transit density with higher total SB in older East Asians; and being an unmarried women with higher SB in the Middle East. We encourage more research in non‐high‐income countries across regions, further exploration of important but neglected correlates using longitudinal designs and qualitative research, and the use of objective instruments to collect SB data.

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Section: Resultsmentioning

confidence: 68%

“…Psychological correlates were examined in six of the 49 studies, five of which regressed them against total SB . Outcome expectations (impact of sitting), self‐efficacy, and perceived social support were not associated with SB in the study on Saudi working women .…”

Section: Resultsmentioning

confidence: 99%

Correlates of sedentary behaviour in Asian adults: A systematic review

et al. 2020

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“…Adjustment for country was conducted by including dummy variables for each country as in previous SAGE publications (Stubbs, Vancampfort, Firth, et al., ; Stubbs Vancampfort, Veronese, et al., ). All variables were included in the models as categorical variables, with the exception of number of chronic physical conditions and age (continuous variables).…”

Section: Methodsmentioning

confidence: 99%

Sedentary behaviour and sleep problems among 42,489 community‐dwelling adults in six low‐ and middle‐income countries

Vancampfort

Stubbs

Firth

et al. 2018

Journal of Sleep Research

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There is a lack of multinational research investigating the association between sleep problems and sedentary behaviour. In this study, we investigated the relationship between the time spent sedentary during waking hours and sleep problems in six low- and middle-income countries. Cross-sectional, community-based data from the Study on Global Ageing and Adult Health survey were analysed. Adjusted logistic regression analyses were undertaken to explore the relationship between self-reported sleep problems (such as difficulties falling asleep, waking up frequently during the night or waking up too early in the morning) in the last 30 days and self-reported sedentary time (categorized as <4, 4 to <8, 8 to <11 or ≥11 hr/day). Among 42,489 individuals aged ≥18 years (mean age=43.8 ± 14.4 years; 50.1% women), those who were sedentary for 8 to <11 hr/day (n = 2,782) and ≥11 hr/day (n = 674) had a 1.61 (95% confidence interval =1.03-2.50) and 1.75 (95% confidence interval =1.17-2.62) times higher odds of having sleep problems, respectively, compared with those being sedentary for less than 4 hr per day (n = 24,637). The strongest associations were observed among those aged 50-64 years. The observed associations were independent of a wide range of sociodemographic factors, physical and mental health conditions and physical activity behaviour. Considering the social and occupational costs of sleep problems, it is important that future longitudinal research should consider the directionality of the data.

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“…It can inevitably predispose individuals to depression due to reductions in activity, social interaction and diversity of daily life, as well as reduced opportunities for work. Sedentary lifestyle has been shown to have a strong independent role in depression risk . Furthermore, the impact of stigmatization, reduction in access to health care and possible reduction in intimate relationships are also factors that may contribute to the relationship between depression and obesity.…”

Section: Discussionmentioning

confidence: 99%

“…Sedentary lifestyle has been shown to have a strong independent role in depression risk. 24,25 Furthermore, the impact of stigmatization, reduction in access to health care and possible reduction in intimate relationships are also factors that may contribute to the relationship between depression and obesity. Biologically, differences in the HPA axis have been proposed as a possible epigenetic basis for depression and obesity.…”

Section: Adjusted Rates Of Depressionmentioning

confidence: 99%

Effect of body mass index on depression in a UK cohort of 363 037 obese patients: A longitudinal analysis of transition

et al. 2019

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With obesity levels increasing, it is important to consider the mental health risks associated with this condition to optimize patient care. Links between depression and obesity have been explored, but few studies focus on the risk profiles of patients across stratified body mass index (BMI) classes above 30 kg/m2. This study aims to determine the impact of BMI on depression risk in patients with obesity and to investigate trends of depression in a large cohort of British patients with BMI > 30 kg/m2. A nationwide primary care database, the Clinical Practice Research Datalink (CPRD), was analysed for diagnoses of obesity (BMI > 30 kg/m2). Obese patients were then sub‐classified into seven BMI categories. Primary health care–based records of patients entered in the CPRD were analysed. A total of 363 037 patients had a BMI ≥ 30 kg/m2; of these patients 97 392 (26.8%) also had a diagnosis of depression. Absolute event rates over time and hazard risk of depression were analysed by BMI category. On Cox regression analysis of time to development of depression, the cumulative hazard increased significantly and linearly across BMI groups (P < 0.001). Compared to those with BMI 30 to 35 kg/m2, patients with BMI 35 to 40 kg/m2 had a 20% higher risk of depression (hazard ratio [HR] 1.206, confidence interval [CI] 1.170‐1.424), and those with BMI > 60 kg/m2 had a 98% higher risk (HR 1.988, CI 1.513‐2.612). This study identified the prevalence and time course of depression in a cohort of obese patients in the United Kingdom. Findings suggest the risk of depression is directly proportional to BMI above 30 kg/m2. Therefore, clinicians should note higher BMI levels confer increased risk of depression.

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Relationship between sedentary behavior and depression: A mediation analysis of influential factors across the lifespan among 42,469 people in low- and middle-income countries

Abstract: People with depression are at increased risk of engaging in high levels of SB. This first multi-national study offers potentially valuable insight for a number of hypotheses which may influence this relationship, although testing with longitudinal studies is needed.

Cited by 123 publications

References 70 publications

Correlates of sedentary behaviour in Asian adults: A systematic review

Correlates of sedentary behaviour in Asian adults: A systematic review

Sedentary behaviour and sleep problems among 42,489 community‐dwelling adults in six low‐ and middle‐income countries

Effect of body mass index on depression in a UK cohort of 363 037 obese patients: A longitudinal analysis of transition

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