Relationship Between Serum Vitamin D Level and Ectopic Pregnancy: A Case-control Study

Abstract

Objective: To compare the difference in Vitamin D level between women with ectopic pregnancy and control group.
 Materials and methods: In the present case-control study, 150 patients with ectopic pregnancy were included as case group and 150 women with normal pregnancy as a control group. Then, serum vitamin D levels were measured in both groups and they were then compared with each other. P value less than 0.05 was considered statistically significant.
 Results: The mean age in ectopic pregnancy group was 28.12 ± 5.91 and 27.35 ± 6.21 years old in control group; the difference between two groups was not statistically significant (p = 0.43). The vitamin D level in control group was higher than that of ectopic pregnancy group (p = 0.002). Of all patients, 182 patients (60.66%) had vitamin D deficiency and 64 patients (21.33%) had vitamin D insufficiency.
 Conclusion: Serum vitamin D level among patients with ectopic pregnancy was statistically lower than women with normal pregnancy.

Association of serum vitamin D levels with ectopic pregnancy

“…[ 14 ] In the present study that was carried out to investigate the association of serum vitamin D levels with the incidence of ectopic pregnancy, it was revealed that the level of vitamin D in healthy pregnant women was significantly higher than the women with ectopic pregnancy, which is consistent with the result of the Sahhaf et al . [ 12 ] study. Besides, Bahat et al .…”

“…[ 10 ] The results achieved from studies have showed that there is a direct relationship between insufficient levels of vitamin D in the blood and the incidence of ectopic pregnancy. [ 11 12 ] Therefore, because of the limited number of studies conducted on this issue on the one hand, and the widespread of vitamin D deficiency, especially among Iranian women on the other hand, in the present study, the association of serum vitamin D levels and ectopic pregnancy during the first trimester was evaluated.…”