Relationship between Sleep Disorders and the Risk for Developing Type 2 Diabetes Mellitus

Ioja, Simona; Weir, Ian; Rennert, Nancy J.

doi:10.3810/pgm.2012.07.2573

Cited by 23 publications

(16 citation statements)

References 92 publications

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“…Sleep is increasingly recognized as an important factor in the homeostasis of multiple body functions [19]. Many adverse health effects such as anxiety, endocrine disorders could hit the body following sleep deprivation [5], [14], [20], [21], [22].…”

Section: Discussionmentioning

confidence: 99%

The Effects of Shift Work on Sleeping Quality, Hypertension and Diabetes in Retired Workers

et al. 2013

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BackgroundShift work has been associated with adverse health effects by disturbing circadian rhythms. However,its potential long-term health effects and the persistent effects after leaving shifts have not been well established.Methods and ResultsWe studied 26,463 workers from Tongji-Dongfeng Cohort in China. All the participants are retired employees of Dongfeng Motor Company. Information on demographics, occupational history and medical history were gathered through questionnaires. After adjusting potential confounders in the logistic regression models, shift work was associated with poor sleeping quality, diabetes and hypertension independently. We observed significant effects of shift work on poor sleeping quality, diabetes and hypertension; the ORs (95%CI) are 1.18 (1.09–1.27), 1.10 (1.03–1.17) and 1.05 (1.01–1.09) respectively. In the further analysis, we found elevated ORs (95%CI) for participants with poor sleeping quality, the ORs (95%CI) are 1.34 (1.08–1.60), 1.13 (1.05–1.21), 1.05 (1.03–1.07) and 1.05 (1.01–1.09) for 1–4, 5–9, 10–19, ≥20 years of shift work respectively. However, with the extension of leaving shift work duration, the effects of shift work on sleep quality gradually reduced.ConclusionsShift work may be an independent risk factor for sleeping quality, diabetes and hypertension even in retired workers. Applicable intervention strategies are needed for prevention of sleep loss, diabetes, and hypertension for shift workers.

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Section: Discussionmentioning

confidence: 99%

The Effects of Shift Work on Sleeping Quality, Hypertension and Diabetes in Retired Workers

et al. 2013

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“…Recently, accumulating evidences have shown that shift work is related with cardiovascular diseases [4,9] and type 2 diabetes [2,10] even in retired populations [11]. Some studies indicated that hypertension and type 2 diabetes were associated with metabolic syndrome (MetS) [12].…”

Section: Introductionmentioning

confidence: 99%

Shift Work and the Relationship with Metabolic Syndrome in Chinese Aged Workers

et al. 2015

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BackgroundShift work is indicated to be associated with adverse metabolic disorders. However, potential effects of shift work on metabolic syndrome (MetS) and its components have not been well established.MethodsIn total, 26,382 workers from Dongfeng-Tongji Cohort were included in this study. Information on shift work history was gathered through questionnaires and metabolic traits were measured. Logistic regression models were used to calculate the odds ratio (OR) and 95% confidence interval (CI) for long-term shift work related with MetS and each component, respectively. Further stratification analysis was performed to detect the differences on MetS between female and male shift workers.ResultsLong-term shift work was associated with MetS without adjusting for any confounders. Compared with the group of non-shift work, the multivariate-adjusted ORs (95%CI) of MetS associated with 1–10, 11−20, and ≥20y of shift work were 1.05 (0.95−1.16), 1.14 (1.03−1.26), 1.16 (1.01−1.31), respectively. In female workers, we found a dose-response relationship that every 10 years increase in shift work was associated with a 10% (95% CI: 1%−20%) elevated OR of MetS, while no significant dose-response trend was found among male workers. Furthermore, shift work duration was significantly associated with ORs of high blood pressure (1.07, 1.01−1.13), long waist circumference (1.10, 1.01−1.20) and high glucose levels (1.09, 1.04−1.15). No significant association was observed between shift work and low HDL cholesterol) and raised triglyceride levels.ConclusionsLong-term shift work was associated with metabolic syndrome and the association might differ by gender in retired workers. Applicable intervention strategies are needed for prevention of metabolic disorders for shift workers.

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“…Sleep deprivation alters glucose homeostasis, leading to insulin resistance and risk of diabetes(17, 18, 24, 59-61). Sleep extension in restricted sleepers may lessen this relationship by improving glucose tolerance(17).…”

Section: Habitual Sleep Duration and Cardiovascular Diseasementioning

confidence: 99%

Sleep

Grandner

Alfonso‐Miller

Fernández-Mendoza

et al. 2016

Current Opinion in Cardiology

126

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Purpose of Review Sleep plays many roles in maintenance of cardiovascular health. This review summarizes the literature across several areas of sleep and sleep disorders in relation to cardiometabolic disease risk factors. Current Findings Insufficient sleep duration is prevalent in the population and is associated with weight gain and obesity, inflammation, cardiovascular disease, diabetes, and mortality. Insomnia is also highly present and represents an important risk factor for cardiovascular disease, especially when accompanied by short sleep duration. Sleep apnea is a well-characterized risk factor for cardiometabolic disease and cardiovascular mortality. Other issues are relevant as well. For example, sleep disorders in pediatric populations may convey cardiovascular risks. Also, sleep may play an important role in cardiovascular health disparities. Summary Sleep and sleep disorders are implicated in cardiometabolic disease risk. This review addresses these and other issues, concluding with recommendations for research and clinical practice.

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Relationship between Sleep Disorders and the Risk for Developing Type 2 Diabetes Mellitus

Cited by 23 publications

References 92 publications

The Effects of Shift Work on Sleeping Quality, Hypertension and Diabetes in Retired Workers

The Effects of Shift Work on Sleeping Quality, Hypertension and Diabetes in Retired Workers

Shift Work and the Relationship with Metabolic Syndrome in Chinese Aged Workers

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