Relationship between Socioeconomic Level, and the Prevalence of Masked Hypertension and Asymptomatic Organ Damage

Ateş, İhsan; Altay, Mustafa; Kaplan, Mustafa; Ozkayar, Nihal; Toprak, Güvenç; Alagüney, Mehmet Erdem; Özkara, Adem

doi:10.12659/msm.892684

Cited by 8 publications

(5 citation statements)

References 22 publications

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“…After adjustment for baseline characteristics, OH was significantly associated with the riser type circadian rhythm (adjusted odds ratio 4.532, 95% CI: 2.579–7.966). The 24‐h ambulatory BP monitoring is a useful non‐invasive technique for evaluating patients with labile hypertension or episodes of hypotension, as it can reflect the patients’ BP fluctuations and circadian rhythms, and thus offers advantages over traditional office BP measurement17, 18. Elevated night‐time BP and non‐dipping profiles have been evaluated in several studies, and it has been shown that elevated night‐time BP, or inverted dippers, is associated with vascular damage, cardiovascular risk and mortality19, 20.…”

Section: Discussionmentioning

confidence: 99%

Blood pressure circadian rhythms and adverse outcomes in type 2 diabetes patients diagnosed with orthostatic hypotension

Chang

Hou

et al. 2017

J of Diabetes Invest

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Aims/IntroductionPatients with diabetes frequently develop orthostatic hypotension (OH). The present study was designed to examine the relationship of blood pressure (BP) circadian rhythms and outcomes in diabetes with OH.Materials and MethodsIn the present study, 173 inpatients with type 2 diabetes were enrolled. Patients were divided into an OH group and a non‐OH group according to the BP changes detected in the supine and standing position. Then, 24‐h ambulatory BP was monitored. Patients were followed up for an average of 45 ± 10 months post‐discharge. Outcomes – death and major adverse cardiac and cerebrovascular events, including heart failure, myocardial infarction and stroke – were recorded.ResultsThere were 61 patients (35.26%) in the OH group and 112 patients (64.74%) in the non‐OH group. In the OH group, the night‐time systolic BP and night‐time diastolic BP were higher, the blood BP rhythms were predominantly of the riser type (67.21%). OH was as an independent marker of riser type circadian rhythm (adjusted odds ratio 4.532, 95% confidence interval 2.579–7.966). In the OH group, the incidence rates of mortality, and major adverse cardiac and cerebrovascular events were increased significantly compared with those in the non‐OH group (11.48 vs 2.68%, P = 0.014; 37.70 vs 8.93%, P < 0.01).ConclusionsIn patients who had type 2 diabetes diagnosed with OH, the BP circadian rhythm usually showed riser patterns, and they had increased rates of mortality, and major adverse cardiac and cerebrovascular events.

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Section: Discussionmentioning

confidence: 99%

Blood pressure circadian rhythms and adverse outcomes in type 2 diabetes patients diagnosed with orthostatic hypotension

Chang

Hou

et al. 2017

J of Diabetes Invest

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“…Взаимосвязь социально-экономических факторов с МАГ была доказана при обследовании жителей бедной окраины Стамбула. МАГ в этом исследовании была выявлена у 15% из них, а бессимптомное ПОМ встречалось чаще, чем у лиц со стабильной АГ, что указывало на длительный анамнез скрытой "персистирующей" гипертензии и отсутствие самоконтроля АД [21]. Расовая принадлежность обследованных также влияет на распространённость МАГ: у лиц европеоидной расы она ниже, чем у лиц негроидной расы.…”

Section: распространенность маг в различных популяцияхunclassified

“…Доказано, в частности, что хронический психоэмоциональный стресс, в том числе на рабочем месте, является предиктором развития МАГ. Результаты психологического тестирования показывают, что распространённость сердечно-сосудистых заболеваний и неблагоприятный кардиоваскулярный прогноз чаще ассоциирован с типом личности Д ("distressed"), для которого характерны тревожные расстройства, негативная аффективность, депрессия и низкий социально-экономический статус [21]. Среди больных МАГ с напряженной трудовой деятельностью и типом личности Д фиксировали избыточную стресс-реактивность гемодинамики в тесте "математический счет", которая проявлялась увеличением систолического АД >7%, диастолического АД >6%, ЧСС >10%.…”

Section: факторы риска и патофизиологические детерминанты магunclassified

“…Так, фенотип МАГ на рабочем месте ассоциируется с видом профессиональной деятельности, интенсивностью воздействия на организм тех или иных стрессоров, психофизиологического статуса отдельных индивидуумов [17,18]. Показана связь между интенсивностью рабочей нагрузки, уровнем АД на рабочем месте и ИММЛЖ [21]. Так, у мужчин в возрасте 30-40 лет интенсивность воздействия стрессоров профессиональной среды прямо коррелировала с повышением диастолического АД на рабочем месте и увеличением ИММЛЖ на 10,8 г/м 2 [19].…”

Section: факторы риска и патофизиологические детерминанты магunclassified

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Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance

et al. 2019

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In most modern studies, masked arterial hypertension (MAH) is characterized as a poorly diagnosed, latent clinical condition predisposing to subclinical damage to target organs and an increased risk of cardiovascular complications. The prevalence of MAH among the population depends on gender, age, anthropometric and socioeconomic factors, profession, race and other characteristics. The most important risk factors (RF) of MAH and its pathophysiological determinants include genetic polymorphism, subclinical non-specific inflammation, hemostatic disorders, obesity, metabolic syndrome, water-salt imbalance, dyslipidemia, hyperuricemia. A defined value has latent dysfunction of the mechanisms that provide circulatory homeostasis, the detection of which is possible by the hemodynamic response to psycho-emotional, hypoxic, hypocapnic, orthostatic effects. Aggressiveness of RF exposure and the consequences of their implementation are evaluated by the rate of development of cardiovascular events and mortality, which indicate an unfavorable prognosis of “uncontrolled” MAH. The maximum reduction of the RF effects and rational pharmacotherapy can significantly improve its clinical prospects.

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“…Masked hypertension (MHT) was first defined by Pickering in 1992, and its importance is progressively increasing (1). MHT is a condition wherein blood pressure measured according to hypertension guidelines in office is normal, whereas the mean 24-h ambulatory blood pressure measurement or blood pressure measurement out of office is high (2).…”

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confidence: 99%

Is thyroid function associated with masked hypertension?

et al. 2016

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Relationship between Socioeconomic Level, and the Prevalence of Masked Hypertension and Asymptomatic Organ Damage

Cited by 8 publications

References 22 publications

Blood pressure circadian rhythms and adverse outcomes in type 2 diabetes patients diagnosed with orthostatic hypotension

Blood pressure circadian rhythms and adverse outcomes in type 2 diabetes patients diagnosed with orthostatic hypotension

Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance

Is thyroid function associated with masked hypertension?

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