Large earthquakes occurring worldwide have long been recognized to be non Poisson distributed, so involving some large scale correlation mechanism, which could be internal or external to the Earth. Till now, no statistically significant correlation of the global seismicity with one of the possible mechanisms has been demonstrated yet. In this paper, we analyze 20 years of proton density and velocity data, as recorded by the SOHO satellite, and the worldwide seismicity in the corresponding period, as reported by the ISC-GEM catalogue. We found clear correlation between proton density and the occurrence of large earthquakes (M > 5.6), with a time shift of one day. The significance of such correlation is very high, with probability to be wrong lower than 10-5. the correlation increases with the magnitude threshold of the seismic catalogue. A tentative model explaining such a correlation is also proposed, in terms of the reverse piezoelectric effect induced by the applied electric field related to the proton density. This result opens new perspectives in seismological interpretations, as well as in earthquake forecast. Worldwide seismicity does not follow a Poisson distribution 1 , not even locally 2. Many authors have proposed specific statistical distributions to describe such a non-poissonian behavior 3-7 but none of these is really satisfactory, probably because the underlying physical process has not been really understood. Many authors have hypothesized that a tidal component may show up in earthquake activity (e.g. 8,9) but generalized evidence has never been proven. Quite recently, some authors 10 suggested that earthquake occurrence might be linked to earth rotation speed variations. There is also a smaller number of researchers that studied possible links among solar activity, electromagnetic storms and earthquakes (e.g. 11-16). The first idea that sunspots could influence the earthquake occurrence dates back 1853, and is due to the great solar astronomer Wolf 17. Since then, a number of scientists has reported some kind of relationship between solar activity and earthquake occurrence 16,18,19 ; or among global seismicity and geomagnetic variation 15,20 or magnetic storms 21,22. Also, some mechanisms have been proposed to justify such correlations: small changes induced by Sun-Earth coupling in the Earth's rotation speed 23 ; eddy electric currents induced in faults, heating them and reducing shear strength 24 ; or piezoelectric increase in fault stress caused by induced currents 25. However, none of these studies allowed achieving a statistically significant conclusion about the likelihood of such mechanisms. On the contrary, 26 argued that there is no convincing argument, statistically grounded, demonstrating solar-terrestrial interaction favoring earthquake occurrence. However, the large interest nowadays for possible interactions between earthquake occurrence and extra-terrestrial (mainly solar) activity, is testified for instance by the Project CSES-LIMADOU, a Chinese-Italian cooperation aimed to launc...