Relationship Between Taurine Intake and Cardiometabolic Risk Markers in Korean Elderly

Jun, Hyosun; Mi-Ja, Choi

doi:10.1007/978-981-13-8023-5_29

Cited by 7 publications

(3 citation statements)

References 14 publications

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“…Consistent with these data, a previous study conducted using data from the Korea National Health and Nutrition Examination Survey (KNHANES) had shown that taurine supplementation can decrease the cardiometabolic risk in male elderly subjects aged 75 and older [173]. Similarly, a double-blind study conducted in 24 women randomly assigned to receive taurine (1.5 g) or placebo (1.5 g of starch) for 16 weeks revealed that taurine supplementation prevented the decrease in SOD plasma levels [141], suggesting taurine as a potential strategy to control oxidative stress during the aging process.…”

Section: Taurine and Longevitysupporting

confidence: 63%

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview

Santulli,

Kansakar,

Varzideh

et al. 2023

Nutrients

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Taurine, a naturally occurring sulfur-containing amino acid, has attracted significant attention in recent years due to its potential health benefits. Found in various foods and often used in energy drinks and supplements, taurine has been studied extensively to understand its impact on human physiology. Determining its exact functional roles represents a complex and multifaceted topic. We provide an overview of the scientific literature and present an analysis of the effects of taurine on various aspects of human health, focusing on aging and cardiovascular pathophysiology, but also including athletic performance, metabolic regulation, and neurological function. Additionally, our report summarizes the current recommendations for taurine intake and addresses potential safety concerns. Evidence from both human and animal studies indicates that taurine may have beneficial cardiovascular effects, including blood pressure regulation, improved cardiac fitness, and enhanced vascular health. Its mechanisms of action and antioxidant properties make it also an intriguing candidate for potential anti-aging strategies.

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Section: Taurine and Longevitysupporting

confidence: 63%

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview

Santulli,

Kansakar,

Varzideh

et al. 2023

Nutrients

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“…It was found that the patients with ratios above the mean 24 h urine Tau/Cr and Mg/Cr ratios of 639.4 and 82.8, respectively, exhibited an inverse relationship with body mass index, total cholesterol in plasma, blood pressure (diastolic and systolic) and atherogenic indices (total cholesterol/HDLc), compared with the patients with lower levels of urinary Tau excretion (204). In support of these findings, a more recent 24 h nutrient analysis study by Jun and Choi similarly reported a negative association between Tau intake and atherogenic index in men, but not in women who appeared to have a positive association between Tau intake and diastolic blood pressure (205). In a human study that included smokers, it was found that Tau was positively associated with endothelial functioning (206).…”

Section: Tau and Atherosclerosismentioning

confidence: 80%

Atherosclerosis Linked to Aberrant Amino Acid Metabolism and Immunosuppressive Amino Acid Catabolizing Enzymes

et al. 2020

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Cardiovascular disease is the leading global health concern and responsible for more deaths worldwide than any other type of disorder. Atherosclerosis is a chronic inflammatory disease in the arterial wall, which underpins several types of cardiovascular disease. It has emerged that a strong relationship exists between alterations in amino acid (AA) metabolism and the development of atherosclerosis. Recent studies have reported positive correlations between levels of branched-chain amino acids (BCAAs) such as leucine, valine, and isoleucine in plasma and the occurrence of metabolic disturbances. Elevated serum levels of BCAAs indicate a high cardiometabolic risk. Thus, BCAAs may also impact atherosclerosis prevention and offer a novel therapeutic strategy for specific individuals at risk of coronary events. The metabolism of AAs, such as L-arginine, homoarginine, and L-tryptophan, is recognized as a critical regulator of vascular homeostasis. Dietary intake of homoarginine, taurine, and glycine can improve atherosclerosis by endothelium remodeling. Available data also suggest that the regulation of AA metabolism by indoleamine 2,3-dioxygenase (IDO) and arginases 1 and 2 are mediated through various immunological signals and that immunosuppressive AA metabolizing enzymes are promising therapeutic targets against atherosclerosis. Further clinical studies and basic studies that make use of animal models are required. Here we review recent data examining links between AA metabolism and the development of atherosclerosis.

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“…Moreover, the same study reported that taurine administration delayed the deterioration of aging-related biomarkers in mice and zebrafish. Taurine is found in food, mainly fish and shellfish, and dietary taurine intake has been reported in South Korea (3)(4)(5). Taurine improves athletic endurance (6) and muscle performance by regulating the release of calcium ions from muscle cells (7).…”

Section: Introductionmentioning

confidence: 99%

Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study

Domoto,

Kise,

Oyama

et al. 2024

Front. Nutr.

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IntroductionTaurine has diverse valuable biological functions, including antioxidant activity and regulation of osmotic pressure. Maintaining physical fitness from middle age is important for healthy life expectancy. Although taurine administration improves muscle endurance and strength, its role in maintenance remains unclear. We aimed to clarify the longitudinal taurine intake association with fitness changes.MethodsParticipants comprised men and women aged ≥40 years who participated in the third (2002–2004; Baseline) and seventh (2010–2012; Follow-up) waves of the National Institute for Longevity Sciences-Longitudinal Study of Aging (NILS-LSA) and completed a 3-day dietary weights recording survey at baseline. A table of taurine content was prepared for 751 foods (including five food groups: Seaweed; Fish and shellfish; Meat; Eggs; and Milk and dairy products) from the Standard Tables of Food Composition in Japan (1,878 foods) 2010. Four physical fitness items (knee extension muscle strength, sit-and-reach, one-leg standing with eyes closed, and maximum walking speed) were measured at baseline and follow-up. We analyzed the association of taurine intake with physical fitness change, employing a general linear model (GLM) and trend tests for baseline taurine intake and follow-up fitness change. Adjustments included baseline variables: sex, age, height, weight, educational level, self-rated health, smoking status, depressive symptoms, and clinical history.ResultsThe estimated average daily taurine intake (standard deviation) was 207.5 (145.6) mg/day at the baseline. When examining the association with the four physical fitness parameters, higher taurine intake positively increased the change in knee extension muscle strength (T1; 0.1, T2; 0.8, T3; 1.1 (kgf) GLM, p < 0.05; p for trend <0.05) and reduced the decline in knee extension muscle strength in the subgroup analysis of participants aged ≥65 years (T1: −1.9, T2: −1.7, T3: −0.4 kgf; GLM p < 0.05, p for trend <0.05). No relationship was found between taurine intake and the remaining three fitness factors.ConclusionEstimation of taurine intake showed that dietary taurine intake potentially contributes to the maintenance of knee extension muscle strength over 8 years among Japanese community-dwelling middle-aged and older individuals. This is the first study to investigate the association of dietary taurine intake with muscle strength.

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Relationship Between Taurine Intake and Cardiometabolic Risk Markers in Korean Elderly

Cited by 7 publications

References 14 publications

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview

Atherosclerosis Linked to Aberrant Amino Acid Metabolism and Immunosuppressive Amino Acid Catabolizing Enzymes

Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study

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