Relationship Between Tocopherol and Serum Lipid Levels for Determination of Nutritional Adequacy*

Horwitt, M. K.; Harvey, C. C.; Dahm, Charles H.; Searcy, M. T.

doi:10.1111/j.1749-6632.1972.tb27878.x

Cited by 483 publications

(184 citation statements)

References 24 publications

Supporting

Mentioning

166

Contrasting

Unclassified

Order By: Relevance

“…Moreover, plasma vitamin E levels are closely related to plasma total lipid levels (Horwitt et al, 1972). Low plasma vitamin E concentrations in neonates are due, mainly, to a low plasma lipid level and they increase postnatally with the dietary a-tocopherol (Ha Èga & Kran, 1982).…”

Section: Discussionmentioning

confidence: 99%

“…Low plasma vitamin E concentrations in neonates are due, mainly, to a low plasma lipid level and they increase postnatally with the dietary a-tocopherol (Ha Èga & Kran, 1982). The plasma tocopherol/total lipid ratio proposed by Horwitt (Horwitt et al, 1972) is the most reliable index routinely available in humans. Martinez found that the ratio was acceptable ( b 0.8) in neonates, although it was still lower than adult values (Martinez et al, 1981).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Plasma and erythrocyte α-tocopherol and plasma retinol concentrations in term infants fed formula enriched with long-chain polyunsaturated fatty acids

et al. 1998

View full text Add to dashboard Cite

Objective: To assess the effect of long-chain polyunsaturated fatty acids (LCPUFA)-and vitamin Esupplemented formula feeding on erythrocyte and plasma a-tocopherol (VE), and plasma retinol (VA) concentrations in neonates and to compare these values with those found in infants feeding on infant formula without LCPUFA or breast milk Setting: University Hospital of Granada, Spain. Subjects: 49 full-term infants. Design and intervention: Subjects who chose not to breast feed were fed either (i) unsupplemented infant formula (F) or (ii) infant formula supplemented with LCPUFA and vitamin E (FL). a-Tocopherol and retinol were measured at 7 days, 1 month and 3 months. Results: Plasma and erythrocyte VE concentrations and plasma VE/total lipids ratio increased signi®cantly in all groups at 1 month of life (P`0.05), but did not change signi®cantly between 1 month and 3 months in any group (P b 0.05). Erythrocyte VE and VA retinol concentrations were higher in infants fed an infant formula than in breast milk-fed infants at 1 month of life (P`0.05). Finally, there were no signi®cant differences in plasma or erythrocyte VE levels, plasma VA or plasma VE/total lipid ratio between any groups at 3 months of life (P b 0.05). Conclusion: Infants fed on LCPUFA-and vitamin E-supplemented infant formula for 3 months have similar vitamin E and A status to infants fed on breast milk or infant formula without LCPUFA supplementation.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Plasma and erythrocyte α-tocopherol and plasma retinol concentrations in term infants fed formula enriched with long-chain polyunsaturated fatty acids

et al. 1998

View full text Add to dashboard Cite

show abstract

“…The concentration of vitamin E has been found to be closely related to serum lipids (Horwitt et al, 1972), and the ratio of serum vitamin E to serum cholesterol was applied to accurately assess the vitamin E status in IBD patients.…”

Section: Methodsmentioning

confidence: 99%

Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls

et al. 2000

View full text Add to dashboard Cite

Objective: Malnutrition is observed frequently in patients with in¯ammatory bowel disease (IBD). Knowledge of the nutritional status in patients with recently diagnosed IBD is limited. The aim of this study was to establish a comprehensive picture of the nutritional status in recently diagnosed IBD patients. Subjects: Sixty-nine IBD patients (23 Crohn's disease (CD) and 46 with ulcerative colitis (UC)) within 6 months of diagnosis and 69 age-and sex-matched population controls were included in the study. Methods: The nutritional status was assessed by: (1) body composition (anthropometry and dual-energy X-ray absorptiometry); (2) dietary intake (dietary history); (3) biochemical indexes of nutrition; and (4) muscle strength (isokinetic dynamometer). Results: Body weight and body mass index were signi®cantly lower in UC patients compared with controls. The mean daily intake of carbohydrates was signi®cantly higher in CD patients and the intakes of protein, calcium, phosphorus, and ribo¯avin were signi®cantly lower in UC patients compared with controls, respectively. Serum concentrations of several nutrients (b-carotene, magnesium, selenium and zinc) were signi®cantly lower in UC patients compared with controls. Serum vitamin B 12 concentration was signi®cantly lower in CD patients. Muscle strength did not signi®cantly differ between IBD patients and controls.

show abstract

“…Plasma vitamin E levels are one method of assessing overall vitamin E status, although other dietary and environmental factors need to be taken into account when interpreting results (Dierenfeld, 1989). Vitamin E is dependent on lipid components for absorption and transportation, so it is important to evaluate blood vitamin E levels relative to blood lipid levels (Horwitt et al, 1972). Since blood cholesterol assay is a routine procedure, cholesterol levels are commonly used as an index of blood lipid levels, with blood ␣-tocopherol levels standardized by calculating ␣-tocopherol : cholesterol ratios.…”

Section: Introductionmentioning

confidence: 99%

Plasma Concentrations of Vitamin E in Six Species of Bustard (Gruiformes: Otididae)

Anderson

Dawodu

Patel

et al. 2002

Journal of Wildlife Diseases

View full text Add to dashboard Cite

Vitamin E (measured as ␣-tocopherol) and cholesterol concentrations were determined in plasma samples collected from 86 clinically healthy captive adult bustards of six species and 23 captive juveniles (6-12 mo old) of two of these species. Adult houbara bustards (Chlamydotis undulata macqueenii) had higher plasma ␣-tocopherol concentrations than juveniles (adult: mean Ϯ SE, 11.07 Ϯ 0.41 g/ml, n ϭ 32; juvenile: 6.33 Ϯ 0.48, n ϭ 12) and higher ␣-tocopherol : cholesterol ratios (adult: 6.09 Ϯ 0.44, n ϭ 12; juvenile: 2.94 Ϯ 0.22, n ϭ 11). No age difference was evident for kori bustard (Ardeotis kori) plasma ␣-tocopherol concentrations (adult: 4.43 Ϯ 0.42, n ϭ 21; juvenile: 4.46 Ϯ 0.26, n ϭ 11) or ␣-tocopherol : cholesterol ratios (adult: 3.67 Ϯ 0.44, n ϭ 20; juvenile: 3.71 Ϯ 0.36, n ϭ 11). Adult houbara bustards had significantly higher (P Ͻ 0.01) ␣-tocopherol concentrations compared with adult rufous-crested (Eupodotis ruficrista; 6.64 Ϯ 0.33, n ϭ 19) and white-bellied (Eupodotis senegalensis; 7.75 Ϯ 0.81, n ϭ 8) bustards, but similar ␣-tocopherol : cholesterol ratios (rufous-crested: 5.56 Ϯ 0.32, n ϭ 18; whitebellied: 5.83 Ϯ 0.43, n ϭ 8). Juvenile houbara bustards had higher plasma ␣-tocopherol concentrations than juvenile kori bustards but similar ␣-tocopherol : cholesterol ratios. Adult houbara bustard plasma ␣-tocopherol levels and ␣-tocopherol : cholesterol ratios did not differ significantly between sexes. The vitamin E status of adult bustards appeared to be influenced by environmental conditions that varied due to species-specific husbandry regimes, but no clear relationship was seen with dietary vitamin E levels. Juvenile bustards did not have higher vitamin E levels than adults, despite being maintained on four-fold dietary vitamin E concentrations and in similar environmental conditions. This paper presents the first published data for plasma vitamin E concentrations in bustards. The plasma ␣-tocopherol and cholesterol concentrations and ␣-tocopherol : cholesterol ratios of captive bustards were similar to those previously reported for omnivorous avian species. Further research is required to determine which components of the identified environmental conditions affect bustard vitamin E status and to confirm whether differences exist between species independent of the variation in their management regimes.

show abstract

Relationship Between Tocopherol and Serum Lipid Levels for Determination of Nutritional Adequacy*

Cited by 483 publications

References 24 publications

Plasma and erythrocyte α-tocopherol and plasma retinol concentrations in term infants fed formula enriched with long-chain polyunsaturated fatty acids

Plasma and erythrocyte α-tocopherol and plasma retinol concentrations in term infants fed formula enriched with long-chain polyunsaturated fatty acids

Comprehensive nutritional status in recently diagnosed patients with inflammatory bowel disease compared with population controls

Plasma Concentrations of Vitamin E in Six Species of Bustard (Gruiformes: Otididae)

Contact Info

Product

Resources

About