Relationship between white blood cell count at admission and short term outcome in patients with acute cerebral infarction

Abstract

Relationship between white blood cell count at admission and short term outcome in patients with acute cerebral infarction Abstract Purpose: We studied the association between admission white blood cell (WBC) count and short term outcome in patients with acute cerebral infarction.Methods: 2808 patients with acute cerebral infarction were included in the study. WBC count and other variables were collected within the rst 24 hours of admission. Clinical outcomes (death or dependency) were evaluated by neurologists during hospitalization.e associations between WBC count and in-hospital death or dependency at discharge were analyzed using a multiple logistic model.Result: Multivariate-adjusted odds ratio (95% con dence intervals) of dependency associated with patients with WBC of 10.0-10.9×10 9 /L, 11.0-11.9×10 9 /L, ≥12.0×10 9 /L were 1.46(0. 87-2. 45), 6.21(3. 70-10. 42) and 7.01(4. 53-10. 87), respectively, when compared with patients with admission WBC counts <10.0x10 9 /L. Multivariate-adjusted odds ratio (95% con dence intervals) of death associated with WBC 10.0-10.9×10 9 /L, 11.0-11.9×10 9 /L and ≥12.0×10 9 /L were 2.098(0. 96-4. 58), 4.79(2. 24-10. 22) and 5.59(3. 14-9. 98), respectively. Conclusion:Increased WBC count at admission was signi cantly and positively associated with in-hospital death or dependency at discharge among patients with acute cerebral infarction.

How to Design Economic Predictive Laboratory Panel Evaluating Acute Ischemic Stroke Outcome

“…Biomarker panels can clarify the pathophysiological mechanisms of AIS and the approach to suitable therapy [26]. In this study, the elevated WBC count was associated with stroke severity at admission as noticed in SSS and more disability at discharge by MRS, these findings are in agreement with Peng et al, (2011) and Nardi et al, (2011) who noticed an increased WBC count at admission was significantly correlated to in-hospital death or disability later on [27] [28]. Also the demonstrated neutrophilia was adjuvant predictor correlated to how much the stroke is severe and the prognosis is bad as observed by SSS and MRS respectively.…”

Correlation of blood glucose levels, HbA1c, hemoglobin and leukocytes with outcome on acute stroke

“…Observations indicate that the number of leukocytes at the time of entry may predict the occurrence of poor outcomes in the short term between patients with acute cerebral infarction. 4 This study has limitations. First, things that can affect blood sugar levels when, HbA1c, Hemoglobin and leukocytes are not adjusted for this study.…”

“…In China there are no large numbers of sample data on the relationship between leukocytes count down entering and short term in clinical outcomes in patients with acute cerebral infarction. 3,4 This study aims to examine the correlation between the time of blood sugar levels, HbA1c, hemoglobin and leukocytes with outcomes in ischemic stroke and acute hemorrhagic stroke.…”

Elevated peripheral leukocyte counts in acute cervical artery dissection

“…In patients with acute IS, increased leukocyte counts were associated with stroke severity and infarct size . Elevated WBC count is an independent predictor of unfavorable outcome in patients with IS , myocardial infarction and peripheral arterial disease .…”