Relationship between work functioning and self-reported cognitive complaints in patients with major depressive disorder treated with desvenlafaxine

Alonso-Prieto, Esther; Rubino, Cristina; Lucey, Megan; Evans, Vanessa; Tam, Edwin M.; Woo, Cindy; Chakrabarty, Trisha; Yatham, Lakshmi N.; Lam, Raymond W.

doi:10.1016/j.psychres.2018.12.062

Cited by 6 publications

(2 citation statements)

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“…Of the 32 studies included in the analysis [ 20 – 51 ], 20 (63%) were cross-sectional, 10 (31%) were longitudinal, and two (6%) were RCTs ( Table 1 ). Of the two RCTs, one investigated the effects of a computerized cognitive training intervention in participants with chronic pain [ 23 ].…”

Section: Resultsmentioning

confidence: 99%

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Self-Reported Cognitive Function in Persons with Nonneurological Chronic Diseases: A Systematic Review

Cuevas

Danesh

Henneghan

2022

Journal of Aging Research

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Background. Globally, one in three adults has a chronic condition. Many chronic diseases that are not neurological in nature (e.g., diabetes and heart failure) are increasingly associated with cognitive symptoms. However, the instruments used to assess cognitive symptoms in those with nonneurologic chronic illness are heterogeneous, and questions remain as to how cognitive symptoms may be related to demographic and clinical outcome variables, neurocognitive test performance, and other patient-reported outcomes. In this review, we describe associations among self-reported cognitive function, cognitive performance, and additional patient-reported outcomes as well as how cognitive symptoms are measured in nonneurologic chronic illness. Method. Multiple databases (PubMed, Medline, CINAHL, PsycInfo, EMBASE, SCOPUS, the Cochrane Library, and Academic Search Complete) were searched for studies from 1990 to 2020 that provided data on self-reported cognitive symptoms in those with nonneurological chronic conditions. Initial search yielded 304 articles, of which 32 met inclusion criteria. Quality assessment was conducted using the Critical Appraisal Skills Programme. Results. Thirty-two total studies were included: twenty cross-sectional, 10 longitudinal, and 2 randomized controlled trials. The tools used to assess self-reported cognitive function in the studies were heterogeneous: 28 unique tools were used. Thirty studies examined associations among self-reported cognitive function and other patient-reported outcomes. In 19 there were significant associations. Six studies showed no significant associations between neuropsychological tests and self-reported cognitive function; another 6 studies found a significant association. Conclusion. Tools to assess cognitive symptoms were heterogeneous. In most studies, self-reported cognitive symptoms were not correlated with neuropsychological test results, but the majority of studies found a strong association between self-reported cognitive function and other patient-reported outcomes. Implications. Consensus on measuring cognitive symptoms would facilitate cross-study comparisons and facilitate scientific progress in those with nonneurological chronic conditions. Based on these results, there is a need to establish a standardized approach for self-reported cognitive function measurement in patients with nonneurologic chronic illness.

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Section: Resultsmentioning

confidence: 99%

“…Depression and fatigue were most predictive [ 40 , 44 ]. Depression severity and worse work functioning were significantly associated with poorer SRCF in depressed patients [ 20 ]. For rheumatoid arthritis patients, sleep quality was significantly associated with SRCF [ 50 ].…”

Section: Resultsmentioning

confidence: 99%

Self-Reported Cognitive Function in Persons with Nonneurological Chronic Diseases: A Systematic Review

Cuevas

Danesh

Henneghan

2022

Journal of Aging Research

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Cognition

Young¹

2021

Burger's Medicinal Chemistry and Drug Discovery

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Cognition can be defined as neurocognitive processes of how humans learn and remember. As humans age, threats of neurocognitive disturbances are probably the most feared psychiatric problems, but these processes also can be disrupted by biological abnormalities closely connected to other psychiatric problems. The theme of this article is that basic research in areas of cognition and advances in the discovery of novel pharmacotherapy for neurocognitive and psychiatric disorders that affect the elderly are inextricably intertwined. Drug evaluations in animal models should be conducted in, three basic types of learning/memory paradigms (habituation, classical conditioning, and operant conditioning) and should assess the effects of agent on learning, retention, and retrieval. The importance of this strategy involves issues of single or multiple learning processes in the paradigms, whether different types of paradigms give rise to different kinds of memories or whether the same paradigm may produce several fundamentally different types of memories that may or may not be interdependent. Medications currently in use for ameliorating neurocognitive disorders are mostly ineffective. New pharmacotherapy is urgently needed, and a seemingly innumerable collection of drugs has been proposed as the latest “key” to unlock mechanisms of dysfunction in neurocognition. In some cases, new agents have functioned (biochemically) exactly as advertised, but virtually all have proved unacceptable for clinically use. Future therapies for neurocognitive disorders will likely benefit from the recognition that multiple cellular mechanisms and neurotransmitter processes are involved and that administration of combinations of agents that provide “wide‐spectrum” actions may be most useful.

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Association between discrepancy in objective and subjective cognitive abilities and treatment response in patients with major depressive disorder: A CAN-BIND-1 study report

Rnic

Jung

Chakrabarty

et al. 2021

Journal of Affective Disorders

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Relationship between work functioning and self-reported cognitive complaints in patients with major depressive disorder treated with desvenlafaxine

Cited by 6 publications

References 40 publications

Self-Reported Cognitive Function in Persons with Nonneurological Chronic Diseases: A Systematic Review

Self-Reported Cognitive Function in Persons with Nonneurological Chronic Diseases: A Systematic Review

Cognition

Association between discrepancy in objective and subjective cognitive abilities and treatment response in patients with major depressive disorder: A CAN-BIND-1 study report

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