2022
DOI: 10.21294/1814-4861-2022-21-4-64-71
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Relationship of -31G/C (rs9904341) polymorphism in the survivin gene <i>BIRC5</i> and the risk of bladder cancer

Abstract: Purpose: To study the relationship between the -31G/C (rs9904341) polymorphism in the promoter region of the survivin protein gene and the predisposition to bladder cancer (BC) in patients of the Krasnoyarsk region. Material and methods. The allelic composition of the studied gene was determined in a group of 158 BC patients, consisting of 30 women and 128 men (mean age 65.6 ± 10.7, median: 66.5; C25–C75: 59–72). The control group included 117 healthy donors and consisted of 27 women and 90 men with an average… Show more

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