Relationship of colonoscopy-detected serrated polyps with synchronous advanced neoplasia in average-risk individuals

High yield of synchronous lesions in referred patients with large lateral spreading colorectal tumors

“…[5][6][7][8][9]11 We also found a high rate of synchronous conventional adenomas in patients with large serrated polyps ≥ 20 mm, but we also demonstrated a high risk of synchronous serrated class lesions in this population. Only two prior studies characterized synchronous lesions in patients with conventional adenomas ≥ 20 mm.…”

“…2 However, this may be attributable to missed synchronous lesions as opposed to early metachronous lesions. Prior studies demonstrated an increased risk of synchronous advanced adenomas in patients with large flat polyps 3 , large sessile adenomas 4 and large serrated polyps [5][6][7][8][9][10][11] .…”

Phenotype Characteristics of Patients With Colonic Serrated Polyposis Syndrome: A Study of 23 Cases

“…9,10,21 Our case series is limited to relating phenotypes with their risk of having or developing CRC. Although in this study we failed to find proximal phenotype-associated synchronous CRC, there is evidence that serrated lesions larger than 10 mm (in particular, sessile adenoma) are a risk factor for developing or having proximal CRC, 22,23 which is not the case for lesions smaller than 5 mm. 23 The extracolonic cancer prevalence that we found (17%) in this case series is similar to that in other reports, despite the fact that none had synchronous CRC, which is described in the literature.…”

“…Although in this study we failed to find proximal phenotype-associated synchronous CRC, there is evidence that serrated lesions larger than 10 mm (in particular, sessile adenoma) are a risk factor for developing or having proximal CRC, 22,23 which is not the case for lesions smaller than 5 mm. 23 The extracolonic cancer prevalence that we found (17%) in this case series is similar to that in other reports, despite the fact that none had synchronous CRC, which is described in the literature. 11,16 Although we found synchronous adenomatous polyps in the 3 phenotypes, a greater amount of coincident adenoma is found in the mixed phenotype.…”

1007 Sessile Serrated Adenoma Detection Rate Is Correlated With Adenoma Detection Rate

“…Previous reports have shown that when a patient presented with serrated lesions, especially SSAs, he/she was also more likely to have advanced neoplasia [23,[27][28][29] . These results were compatible with previous reports and suggested that ADR is correlated with SSADR.…”