Relationship of corneal hysteresis and optic nerve parameters in healthy myopic subjects

Qiu, Kunliang; Lu, Xuehui; Zhang, Riping; Wang, Geng; Zhang, Mingzhi

doi:10.1038/s41598-017-15386-6

Cited by 8 publications

(7 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…49,[52][53][54] Park et al 49 report no significant association between CCT, CH, or CRF with the mean RNFL thickness, although after adjustment, CH and RNFL were directly associated (ß = 0.013, P = 0.043) in NTG patients. In studies measuring RNFL using OCT, no association was found between CH and CRF, and RNFL thickness in suspect or confirmed OAG, as well as in healthy myopic eyes, 52,53 except for one study in which the relationship between CH and RNFL thickness was significant (ß = 0.2, P = 0.001) in OAG. 54 The results of our study did not find a significant correlation between the average RNFL thickness and CH or CRF, but did find a correlation with CCT, as shown in Table 2.…”

Section: Discussionmentioning

confidence: 98%

The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma

Sayah

Mazzaferri

Descovich

et al. 2020

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

PURPOSE. Ocular rigidity (OR) is an important biomechanical property, thought to be relevant in the pathophysiology of open-angle glaucoma (OAG). This study aims to evaluate the relationship between OR and neuroretinal damage caused by glaucoma. METHODS. One hundred eight subjects (22 with healthy eyes, 23 with suspect discs, and 63 with OAG) were included in this study. OR was measured using a noninvasive optical coherence tomography (OCT)-based method developed by our group. We also measured central corneal thickness (CCT), corneal hysteresis (CH), and corneal resistance factor (CRF). Pearson and partial correlations were performed to evaluate the relationship between OR and glaucomatous damage represented by ganglion cell complex (GCC), retinal nerve fiber layer (RNFL) thicknesses, and neuroretinal rim area.

show abstract

Section: Discussionmentioning

confidence: 98%

The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma

Sayah

Mazzaferri

Descovich

et al. 2020

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

“…For hyperopic and for female patients, higher values for CRF have been observed. For highly myopic patients, other studies have registered lower values of the CH and CRF and higher values of IOPcc (Corneal Compensated Intraocular Pressure) and of IOPg (Goldmann Correlated IOP value) compared to the emmetropic, hyperopic patients or patients with medium or low myopia [ 31 - 34 ].…”

Section: Discussionmentioning

confidence: 99%

Correlations between corneal biomechanics and specular microscopy in patient with cataract

Iancu

Bujor

Iliuţă

et al. 2020

rjo

View full text Add to dashboard Cite

This study aimed to analyze the connection between corneal biomechanics (corneal hysteresis, CH) and endothelial cell density of cornea (mean endothelial cell density, MCD) in patients diagnosed with cataract. This retrospective, observational study was performed in the Ophthalmology Clinic of the University Emergency Hospital in Bucharest. Of 60 patients (120 eyes) with cataract, who were included in this study, we analyzed the CH values obtained using with the Ocular Response Analyzer (ORA) and the MCD values obtained using the specular microscopy. The study groups comprised both men and women with ages ranging from 45 to 63 years. Patients were divided into three study groups according to CH values. In each batch, the CH values obtained with the Ocular Response Analyzer (ORA) were correlated with age, gender and MCD, then the subgroups were compared. All the data gathered showed no correlation to be statistically significant regarding the biomechanical properties of the cornea and the corneal endothelial cell density in patients with cataract.

show abstract

“…Quantification of corneal biomechanics has helped us to understand the changes in corneal shape and structure after refractive surgery [1,2]. The corneal stiffness is a recently described index with clinical significance for the detection in patients who are at risk of ectasia development [3,4]. Previous studies have shown that the biomechanical properties of the cornea are correlated with many factors such as central corneal thickness (CCT) and intraocular pressure (IOP) [5,6].…”

Section: Introductionmentioning

confidence: 99%

Effect of biomechanical properties on myopia: a study of new corneal biomechanical parameters

Fang

Wei

et al. 2020

BMC Ophthalmol

View full text Add to dashboard Cite

Background To assess the corneal stress-strain index (SSI), which is a marker for material stiffness and corneal biomechanical parameters, in myopic eyes. Methods A total of 1054 myopic patients were included in this study. Corneal visualisation Scheimpflug technology was used to measure the SSI. Corneal biomechanics were assessed using the first and second applanation times (A1-and A2-times); maximum deflection amplitude (DefAmax); deflection area (HCDefArea); the highest concavity peak distance (HC-PD), time (HC-time), and deflection amplitude (HC-DefA); integrated radius (IR); whole eye movement (WEM); stiffness parameter (SP-A1;, biomechanically corrected intraocular pressure (BIOP); and Corvis biomechanical index (CBI). Scheimpflug tomography was used to obtain the mean keratometery (Km) and central corneal thickness (CCT). According to the spherical equivalent (SE) (low myopia: SE ≥ − 3.00D and high myopia: SE ≤ − 6.00D.), the suitable patients were divided into two groups. Results The mean SSI value was 0.854 ± 0.004. The SSI had a positive correlation with A1-time ((r = 0.272), HC-time (r = 0.218), WEM (r = 0.288), SP-A1 (r = 0.316), CBI (r = 0.199), CCT (r = 0.125), bIOP (r = 0.230), and SE (r = 0.313) (all p-values<0.01). The SSI had a negative correlation with HCDefA (r = − 0.721), HCDefArea (r = − 0.665), HC-PD(r = − 0.597), IR (r = − 0.555), DefAmax (r = − 0.564), and Km (r = − 0.103) (all p-values<0.01). There were significant differences in SSI (t = 8.960, p<0.01) and IR (t = − 3.509, p<0.01) between the low and high myopia groups. Conclusions In different grades of myopia, the SSI values were lower in eyes with higher SEs. It indicates that the mechanical strength of the cornea may be compromised in high myopia. The SSI was positively correlated with the spherical equivalent, and it may provide a new way to study the mechanism of myopia.

show abstract

Relationship of corneal hysteresis and optic nerve parameters in healthy myopic subjects

Cited by 8 publications

References 26 publications

The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma

The Association Between Ocular Rigidity and Neuroretinal Damage in Glaucoma

Correlations between corneal biomechanics and specular microscopy in patient with cataract

Effect of biomechanical properties on myopia: a study of new corneal biomechanical parameters

Contact Info

Product

Resources

About