Relationship of fasting total homocysteine, high sensitivity C-reactive protein and features of the metabolic syndrome in Trinidadian subjects

Abstract

Serum C-reactive protein is significantly related to features of the metabolic syndrome. Total plasma homocysteine, appears to be independent of both hs-CRP and features of the metabolic syndrome.

Castelli risk indexes 1 and 2 are higher in major depression but other characteristics of the metabolic syndrome are not specific to mood disorders

“…Associated lipid / lipoprotein abnormalities include reductions in high density lipoprotein (HDL) cholesterol and increased total cholesterol, LDL and triglyceride levels [8]. Some, but not all studies, reported increased homocysteine levels in the metabolic syndrome [11], and homocysteine is a putative biomarker for depression and bipolar disorder [12,13].…”

Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis

“…A total of 66 articles were included, including 9 cohort studies, 48 cross-sectional studies, and 13 case-controls. As four articles ( 41 , 51 , 60 , 68 ) had analyzed the association in two different groups of participants each, a total of 70 records were included. The geographic distribution was as follows: China (11 articles), South Korea (9 articles), Turkey (7 articles), United States (6 articles), Italy (3 articles), Iran (3 articles), India (3 articles), Serbia (2 articles), Bangladesh (2 articles), France (2 articles), Saudi Arabia (2 articles), Spain (1 article), Ecuador (1 article), Netherlands (1 article), Canada (1 article), Taiwan (1 article), Australia (1 article), Romania (1 article), Trinidad & Tobago (1 article), Nigeria (1 article), Poland (1 article), Greece (1 article), South Africa (1 article), Slovenia (1 article), Cameroon (1 article), Peru (1 article), and multiple Mesoamerican countries (1 article).…”