The work presents a multi-aspect model of alimentary-dependent diseases (ADD) prevention, which demonstrates the participants in this process and their priority tasks. A method is proposed based on the use of indicators for assessing the iodine-containing products contribution to the nutritional value of diets. Calculations were performed on a micronutrient - iodine, the deficiency of which causes the most common by depth and width ADD - thyroid pathology. To assess the iodine replenishing potential of raw fish and non-fish sea foods with the human diet, indicators were developed that account along with the iodine content in 100 g of product, the factors that directly or indirectly affect the digestibility and the economic feasibility of some of the most in-demand fish varieties. Selected factors: native iodine content in the product; qualitative and quantitative composition of synergistic nutrients for its digestibility in the body. Deviations of the reference data on the content of iodine in fish and non-fish products were found, which on average amounted to about 45 %, which is a significant loss that must be taken into account when using the calculated method of actual nutrition study.