Relationship of Nutritional Status and Spirometric Parameters in Children with Bronchial Asthma

Khramova, R.N.; Tush, E.V.; Khramov, A.A.; Ovsyannikov, D.Yu.; Popov, K; Dolbin, I. V.; Khaletskaya, O.V.; Строганов, А. Б.; Kubysheva, Nailya; Eliseeva, T.I.

doi:10.17691/stm2020.12.3.02

Cited by 5 publications

(2 citation statements)

References 53 publications

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“…Our data are consistent with the results obtained by the research groups Khrisanapant et al [16], Xu et al [17], and Han et al [18], who also note that as BMI increases, the ratio of FEV 1 /FVC is observed in children and adolescents with BA [19]. The results obtained are also consistent with our pilot study [20].…”

Section: Discussionsupporting

confidence: 93%

Effect of overweight and obesity on spirometric parameters in children and adolescent with asthma

Khramova,

Eliseeva,

Tush

et al. 2023

Exploration of Medicine

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Aim: Being overweight and obesity are factors in the negative modification of bronchial asthma (BA). The mechanisms of the aggravating effect of obesity on the course of BA have not yet been fully determined, but include changes in external respiration. The aim of the study was to study the effect of being overweight/obesity on spirometric parameters and on the occurrence of dysanapsis in children and adolescents with BA. Methods: It was a cross-sectional, open, single-center study. The data were obtained from 428 patients with atopic BA aged 7 years to 17 years, 12.0 [9.0; 14.0], and 72.9% (312/428) of them were boys. The children were divided into 3 groups: group 1—normal body weight; group 2—overweight; and group 3—obesity. All participants underwent spirometry, the ratio of forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) was calculated and the diagnosis of dysanapsis was performed. Results: As body weight increases, a progressive decrease in FEV1/FVC is revealed—group 1: 79.55% [71.37; 85.43]; group 2: 76.82% [70.12; 82.03]; and group 3: 76.28% [67.04; 79.89] P = 0.004; as well as a decrease in Z FEV1/FVC: group 1—1.23 [–2.18; –0.28]; group 2—1.54 [–2.19; –0.68]; and group 3—1.75 [–2.63; –0.90] P = 0.02. Dysanapsis was detected in 37.7% (159/428) of patients. The incidence of dysanapsis increased statistically significantly with increasing body mass index (BMI) and amounted to: with normal body weight—31.7% (77/243), with overweight—42.0% (55/131), and with obesity—50% (27/54) P = 0.016. Conclusions: In children and adolescents with BA, as BMI increases, there is a statistically significant decrease in the ratio of FEV1/FVC, and, consequently, bronchial patency; the incidence of dysanapsis also increases statistically significantly. Taken together, this indicates the formation of an obstructive pattern of external respiration under the influence of being overweight and obesity in children and adolescents with BA.

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Section: Discussionsupporting

confidence: 93%

Effect of overweight and obesity on spirometric parameters in children and adolescent with asthma

Khramova,

Eliseeva,

Tush

et al. 2023

Exploration of Medicine

Self Cite

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“…Allergology and Immunology in Pediatrics. 2022; 2: 50-52. https://doi.org/10.53529/2500-1175-2022-2-50-52 Вступление В настоящее время продемонстрировано, что ожирение оказывает неблагоприятное влияние на течение бронхиальной астмы (БА), включая негативное воздействие на параметры внешнего дыхания [1,2].…”

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Nasal respiratory function in children with bronchial asthma and obesity

Khramova

Tush

Eliseeva

et al. 2022

Allergol. immunol. pediatr.

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Frequency and risk factors of simple obesity in children with bronchial asthma

Алимова

Yacheykina

2023

Ross. vestn. perinatol. pediatr.

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Currently, it has been established that obesity in children with bronchial asthma leads to a more severe course of the disease, a worse quality of life, and a reduced response to treatment.Purpose. To study the incidence and risk factors of simple obesity in children with bronchial asthma. The aim of the study was to study the incidence and risk factors of simple obesity in children with bronchial asthma.Material and methods. The study included 484 patients aged 7 to 14 years: the main group consisted of 237 patients with atopic bronchial asthma, the comparison group consisted of 247 children without a diagnosis of bronchial asthma.Results. Patients of the main group were obese more often (18.9%) than children of the comparison group (11.3%, p=0.019). During 5 years of bronchial asthma disease, a tendency (p=0.087) was revealed to increase the SDS body mass index indicator in the dynamics of the disease (from 0.32 to 0.45) and the number of patients with III and IV degrees of obesity (from 10.5% to 42.8%, p=0.025). In children of the main group with normal SDS body mass index before the diagnosis of bronchial asthma 5 years after the onset of the disease, in 8.5% of cases there was obesity (p<0.001) and in 23.9% — excess body weight (p<0.001), in children with initial excess body weight, obesity was diagnosed in 28.6% of cases (p=0.048), and among children who were obese at the time of bronchial asthma, 26.3% had an increase in its severity (p=0.023). In patients with bronchial asthma and obesity, according to the bioimpedance analysis findings, a pronounced imbalance between energy intake and its consumption was revealed, and according to the nutrition assessment data — an unbalanced diet, a violation of the diet and a sedentary lifestyle.Conclusion. Simple obesity occurs in 18.9% of school-age children with atopic bronchial asthma, and over the course of 5 years of the disease, the number of patients with obesity increases and its severity progresses. Therefore training of patients and their parents, correction of nutrition and increasing the volume of physical activity are an important component of treatment.

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Relationship of Nutritional Status and Spirometric Parameters in Children with Bronchial Asthma

Cited by 5 publications

References 53 publications

Effect of overweight and obesity on spirometric parameters in children and adolescent with asthma

Effect of overweight and obesity on spirometric parameters in children and adolescent with asthma

Nasal respiratory function in children with bronchial asthma and obesity

Frequency and risk factors of simple obesity in children with bronchial asthma

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