Relationship of Pancreatic Mass Size and Diagnostic Yield of Endoscopic Ultrasound-Guided Fine Needle Aspiration

Siddiqui, Ali A.; Brown, Lauren J.; Hong, Shih-Kuang S.; Draganova‐Tacheva, Rossitza; Korenblit, Jason; Loren, David E.; Kowalski, Thomas E.; Solomides, Charalambos

doi:10.1007/s10620-011-1782-z

Cited by 112 publications

(81 citation statements)

References 27 publications

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“…The presence of biliary plastic stents has been reported to diminish the rate of EUS-FNA [30], but it did not influence our results, although biliary stents were seen in about 10% of our cases, as in the other study [30]. As already known from the cytology assessment, the diagnostic accuracy of core biopsy is not related to the mass size or the presence of necrosis inside, facts previously reported also by our group [21,[31][32][33].…”

Section: Discussionsupporting

confidence: 67%

Performance of the Standard 22G Needle for Endoscopic Ultrasound-guided Tissue Core Biopsy in Pancreatic Cancer

Seicean

Gheorghiu

Zaharia

et al. 2016

JGLD

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Background & Aim: Endoscopic ultrasonography (EUS) and EUS-guided fine-needle aspiration (EUS-FNA) are considered good tools for the diagnosis of pancreatic cancer and for obtaining material for cytology or histology. The accuracy of EUS-FNA can rise to 85-95%, but it is lower in cases with a chronic pancreatitis background or with previous biliary stenting. We aimed to establish the diagnostic yield of the visible length of the core biopsy samples in pancreatic cancer by using one single type of standard 22G needle and to evaluate the factors which can influence the results. Method: EUS-FNA was performed by using a 22G standard needle on patients prospectively recruited with the suspicion of pancreatic masses on transabdominal ultrasound or CT scan over a period of eight months. The number of passes was limited by the length of the core obtained. The final diagnosis was based on EUS-FNA or hepatic biopsy for their metastasis or by follow up every three month by imaging methods. Results: The study included 118 patients. Previous stents were present in 10 patients and chronic pancreatitis features were found in 3 patients. The procedure sensitivity was 89% and the global accuracy was 89%. The presence of biliary stents did not impede the accuracy of results. The number of passes did not influence the results. Conclusions: The diagnostic rate of core biopsy by using 22G needles had a high accuracy and it is safe when the length of core dictates the number of passes. The presence of biliary stents did not influence the results. Abbreviations: AUC: area under the curve; EUS: endoscopic ultrasonography; EUS-FNA: fine needle aspiration under endosonographic guidance; FNA: fine needle aspiration; INR: international normalised ratio; OR: odds ratio.

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Section: Discussionsupporting

confidence: 67%

Performance of the Standard 22G Needle for Endoscopic Ultrasound-guided Tissue Core Biopsy in Pancreatic Cancer

Seicean

Gheorghiu

Zaharia

et al. 2016

JGLD

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“…However, some authors have found that the sensitivity and the diagnostic accuracy of EUS-FNA of solid pancreatic lesions decreases significantly with size B2 cm [7][8][9].…”

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confidence: 99%

Endoscopic ultrasound-guided fine-needle biopsy of small solid pancreatic lesions using a 22-gauge needle with side fenestration

et al. 2014

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“…For example, tumor size has been shown to affect the diagnostic yield. 26 Fine-needle aspiration DTA studies show wide variation in accuracy, and it is possible that population differences may account for some of this variability. The role of population differences will most likely be revealed through analysis of heterogeneity in meta-analytic studies.…”

Section: Commentmentioning

confidence: 99%

Diagnostic Accuracy Studies of Fine-Needle Aspiration Show Wide Variation in Reporting of Study Population Characteristics: Implications for External Validity

Schmidt

Witt

Factor

2014

Archives of Pathology &Amp; Laboratory Medicine

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Context.-Study comparisons rest on the assessment of applicability or external validity. Population characteristics are an important component of external validity and, although there has been a heightened awareness of deficiencies in reporting in diagnostic test accuracy (DTA) studies, the reporting of populations in DTA studies has not been investigated.Objective.-To assess the quality of reporting of population descriptions in DTA studies for fine-needle aspiration cytology (FNAC).Design.-Literature survey of common population parameters and usage patterns in FNAC DTA studies. We randomly selected 20 FNAC DTA studies in 4 categories (salivary glands, lung, thyroid, and pancreas) and determined the frequency of parameter usage.Results.-Studies showed considerable variability in reporting patterns. On average, studies reported 2 to 4 parameters to describe study populations. Age, sex, and lesion size were most frequently reported. Sixteen percent of studies did not provide any population description. Population parameters were used to describe the sample population more frequently than to describe the selection process (P ¼ .001). There were significant differences in the number of parameters specified by anatomic site (P ¼ .001). Only 21% of studies provided a flow diagram. Thirty-three percent of studies mentioned the target population.Conclusions.-Studies show considerable variability in the description of sample populations and the population selection process. Studies often fail to provide flow diagrams or to provide a clear statement of the research problem. There is considerable opportunity for studies to improve both descriptions of sample populations and the process used to select them.

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Relationship of Pancreatic Mass Size and Diagnostic Yield of Endoscopic Ultrasound-Guided Fine Needle Aspiration

Abstract: The sensitivity and diagnostic accuracy of EUS-FNA for solid pancreatic lesions is strongly correlated with tumor size. Sensitivity and accuracy decrease significantly for tumors that are smaller than 1 cm.

Cited by 112 publications

References 27 publications

Performance of the Standard 22G Needle for Endoscopic Ultrasound-guided Tissue Core Biopsy in Pancreatic Cancer

Performance of the Standard 22G Needle for Endoscopic Ultrasound-guided Tissue Core Biopsy in Pancreatic Cancer

Endoscopic ultrasound-guided fine-needle biopsy of small solid pancreatic lesions using a 22-gauge needle with side fenestration

Diagnostic Accuracy Studies of Fine-Needle Aspiration Show Wide Variation in Reporting of Study Population Characteristics: Implications for External Validity

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