Analyzing and fusing information layers of exploratory parameters is a critical step for enhancing the accuracy of identifying mineral potential zones during the reconnaissance stage of mineral exploration. The Qixia area in Shandong Province is characterized by intricate geological structures and abundant mineral resources. Numerous gold polymetallic deposits have been discovered in this region, highlighting the potential for discovering more such deposits in the ore concentration zone and its adjacent areas. In this study, we focus on the Qixia area and employ the box dimension method to analyze the fractal dimension of fault structures. We investigate the relationship between orebody occurrence and fault incidence within the mining region. Furthermore, we combine fractal analysis with Fry analysis to comprehensively predict the metallogenic potential in the area. This study reveals the fractal dimension values of fault structures, demonstrating that fault structures govern the distribution of ore bodies, with NE and NW fault structures being the primary ore-hosting features. Based on thorough analysis, we hypothesize that gold deposits in this area are generally distributed along the northeastern direction. By considering mineral distribution characteristics, this study identifies five potential metallogenic prospect areas within the study region. Capitalizing on advancements in information technology and big data, digital geology has gained prominence in prospecting and prediction. To this end, we construct a multi-information comprehensive prospecting model based on the structure-geochemical anomaly-mineralization alteration, employing the convolutional neural network (CNN) model for quantitative estimation of regional gold mineral resources. The findings validate the CNN model’s robust prediction performance in this area, leading to the determination of five prediction prospects. We observe a notable congruence between the two methods, offering significant insights for subsequent exploration endeavors in the region.