Relationship of Weight Gain During Pregnancy to Birth Weight and Infant Growth and Development in the First Year of Life

Singer, Judith E.; Westphal, Milton; Niswander, Kenneth R.

doi:10.1097/00006250-196803000-00021

Cited by 110 publications

(41 citation statements)

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“…It is well known that both pre-pregnancy weight and weight gain can strongly influence BP [53] and fetal growth [54,55]. In this study, however, there was no difference in either variable between women with uncomplicated pregnancies and women with pregnancies complicated by IUGR, or between normotensive women and women with PIH.…”

Section: Discussioncontrasting

confidence: 71%

Circadian rhythm of maternal blood pressure and fetal growth

Maggioni¹,

Cornelissen²,

Otsuka³

et al. 2005

Biomedicine & Pharmacotherapy

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This study aimed at examining any relation between the circadian variation in blood pressure (BP) in human pregnancy and fetal growth. A prospective study included 52 pregnant women monitored during the third trimester of pregnancy. There were 33 uncomplicated pregnancies with normal fetal growth (Group 1) and 19 pregnancies complicated by intrauterine growth retardation (IUGR), confirmed at birth (Group 2). Ten women (five in each group) had pregnancy-induced hypertension. All women were hospitalized and followed a similar daily routine. BP was recorded with an automatic wearable device. Measurements were obtained every 20 min for 24 ± 1 h. BP profiles were analyzed by conventional statistical methods and by cosinor, involving the least squares fit of cosine curves with an anticipated period (24 h) to the data. BP parameters, fetal outcome, demographic and obstetric characteristics were compared between the two groups. Logistic regression and multivariate analyses were used to assess factors putatively associated with fetal outcome. The circadian amplitude of diastolic BP was found to be larger in normotensive women with IUGR. As gauged by odds ratios (OR), the circadian amplitude of diastolic BP (OR = 1.7, 95% CI: 1.1-2.8; P = 0.03) and hematocrit (OR = 1.4, 95% CI: 1.0-1.9; P = 0.04) were the only variables positively and independently associated with IUGR. In the presence of maternal hypertension, the circadian amplitude of systolic BP was negatively associated with IUGR (OR = 0.7, 95% CI: 0.5-1.0; P = 0.03). A larger circadian variation in diastolic BP, rather than a difference in the mean value of systolic or diastolic BP, was found to be statistically significantly associated with IUGR. This study adds another condition in which the circadian BP amplitude constitutes a harbinger of elevated risk, apart from an association with a shortened lifespan in the absence or presence of malignant hypertension and with an increased risk of stroke and nephropathy reported earlier.

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Section: Discussioncontrasting

confidence: 71%

Circadian rhythm of maternal blood pressure and fetal growth

Maggioni¹,

Cornelissen²,

Otsuka³

et al. 2005

Biomedicine & Pharmacotherapy

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“…Die mütterliche Ernährung ist damit ein wichtiger Faktor in der pränata-len Betreuung. Dies ist besonders bekannt seit den wegweisenden Studien vor 30 Jahren über die Beziehung zwischen mütterlichem Gewicht vor der Schwangerschaft, der Gewichtszunahme während der Schwangerschaft und dem Geburtsgewicht des Kinds [61]. Wenn das Geburtsgewicht des Kinds, wie Barker [5] darlegte, mit der Mortalität an Herz-und Kreislaufkrankheiten und anderen Krankheiten beim Erwachsenen korreliert, so werden Begriffe wie Programmierung bereits mit der intrauterinen Entwicklung und Gewichtszunahme in Zusammenhang gebracht.…”

Section: Schwangerschaft Und Laktation Sindunclassified

Prävention beim Kind durch Ernährung der Schwangeren und Stillenden?

Baerlocher

1998

Monatsschr Kinderheilkd

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“…Obesity is also a risk factor for spontaneous abortion, and the pregestational effect of obesity on glucose metabolism has profound effects on the human body up to and including such feared complications as retinopathy, neuropathy, and nephropathy. [10][11][12][13][14][15] There are 2 final points to consider regarding information that is obtained in a general medical history. First, if provider concerns are aroused regarding deficiencies or excesses of calories, vitamins, minerals, or other substances, then a general laboratory screen could be helpful to detect potential deficiencies.…”

mentioning

confidence: 99%