Relationships between leptin, the KiSS-1/GPR54 system and thyrotropic axis activity in ewe lambs predisposed to the delayed puberty

Radwańska, Paulina; Kosior-Korzecka, U.

doi:10.1016/j.smallrumres.2016.07.019

Cited by 4 publications

(2 citation statements)

References 51 publications

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“…On the other hand, serum leptin levels were at least 3 ng/ml for all BWs lambs in previous study (Altmann et al 2006). Additionally, in the present study, leptin level increase was approximately 30% (no data info) until 40 kg but Altmann et al (2006) reported that leptin increase was more than 30% between 30-35 kg BW, also Radwanska and Kosior-Korzecka (2016) Orman et al (2008Orman et al ( , 2010 UFT was increased with the increase of live weight of Awassi lambs. Also, a similar result was reported by Altmann et al (2005) for different breeds (East Frisian and Blackheaded Mutton Â East Frisian crosses).…”

Section: Resultscontrasting

confidence: 52%

The usefulness of leptin measurements and ultrasound fat thickness for assessment of body fat reserves of Awassi lambs

Orman

Caliskan

Temizel

et al. 2018

Italian Journal of Animal Science

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The objective of this study was to investigate the usefulness of leptin measurements for predicting back fat thickness and the amount of carcase fat in lambs with varying body weights (BWs). Blood samples were taken from 20 male Awassi lambs at 20, 25, 30, 35, and 40 kg BW. Tail, omental, dissected, and total fat were measured at slaughter (40 kg BW). Ultrasound fat thickness (UFT) increased with BW (p < .05) whereas leptin concentration tended to increase (p ¼ .09). Serum leptin concentration was correlated with BW for 25, 30, 35, and 40 kg BW (r ¼ 0.53, 0.52, 0.51 and 0.61, respectively; p < .05) and with UFT for 30, 35, and 40 kg BW (r ¼ 0.50, 0.51 and 0.59, respectively; p < .05); therefore it appears that leptin concentration is not a suitable predictor for BW and UFT in low BW lambs. In addition, similar correlations were found for leptin concentration and hot carcase, omental, dissected, and total fat weights (r ¼ 0.62, 0.64, 0.66 and 0.76, respectively; p < .05) but not for tail fat (p >.05 for 40 kg BW). The introduction of UFT and BW as independent variables in addition to leptin in the multiple regression equations improved the predictions for carcase fat only (57.6%, p < .05; 57.8%, p < .05 and 60.7%, p > .05 for leptin, leptin þ UFT and leptin þ BW, respectively). Leptin was a single predictor for omentum and dissected fat (41.4%, p < .05 and 43.5%, p < .05 respectively) whereas no improvement was observed for tail fat (p > .05). The other variables (UFT and BW) were not a predictor (p > .05) except for total fat (p > .05). These results indicate that serum leptin concentration in association with BW and UFT could be used to estimate total fat (tail, omental and dissectible carcase fat) in male Awassi lambs. ARTICLE HISTORY

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Section: Resultscontrasting

confidence: 52%

The usefulness of leptin measurements and ultrasound fat thickness for assessment of body fat reserves of Awassi lambs

Orman

Caliskan

Temizel

et al. 2018

Italian Journal of Animal Science

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“…Consequently, the increment in plasma fatty acids concentration is observed. Additionally, there was found that in ewe lambs, especially born to obese sheep carrying twins or triplets and characterised by high daily body mass gains, the augmented plasma concentrations of leptin (10) as well as palmitic and stearic acid were in positive correlation with delay in puberty. There are some reports showing that fatty acids may be involved in modulation of pituitary hormones secretion.…”

Section: Praca Oryginalnamentioning

confidence: 99%

Use of rapid immunochromatographic tests and PCR for the detection of vaccine viruses (CPV, CDV CAV) in faeces and conjunctival sac swabs of vaccinated dogs

SZYSIAK,

KOSIOR-KORZECKA,

LONGO

et al. 2023

Medycyna Weterynaryjna

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The pathologically changed pattern of gonadotropin secretion, responsible for ovulation disorders in fatty ewes, may result from the prolonged increase in leptin concentration as well as from diminution of leptin receptors expression in anterior pituitary cells. Leptin acting peripherally reduces the secretion of insulin – the potent inhibitor of lipolysis. Consequently, an increment in plasma fatty acids level is observed. It was also found that in ewe lambs born to obese sheep carrying twins or triplets, a high plasma level of saturated fatty acids (SFA) is in positive correlation with the delay in puberty. However, the relationship between SFA and gonadotropin secretion from the ovine pituitary cells in pubescent ewe lambs is not clear. Therefore, the aim of the study was to establish the effect of SFA on GnRH-induced secretion of FSH and LH. Pituitary glands were isolated from 7 month old ewe lambs. Pituitary cells were cultured in McCoy 5A medium without GnRH and SFA (negative control), with GnRH only (positive control), with GnRH and 10–9-10–3 M/l of the butyric (C4:0), caprylic (C8:0), lauric (C12:0), palmitic (C16:0) or stearic acid (C18:0). After 2 or 6 h of exposure to SFA followed by 2, 6, 12, 18, 24 or 30 h incubation, the media for LH and FSH analysis were collected. It was found that all used SFA reduce GnRH-induced LH and FSH secretion from pituitary cells in vitro. The most significant (P ≤ 0.05) suppressive effect was observed after 6 h exposure of cells to 10–3 M/l of caprylic acid, 10–4 M/l of palmitic acid and 10–4 M/l of stearic acid compared to the positive control.

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Associations of feed efficiency with circulating IGF-1 and leptin, carcass traits and meat quality of lambs

et al. 2021

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Relationships between leptin, the KiSS-1/GPR54 system and thyrotropic axis activity in ewe lambs predisposed to the delayed puberty

Cited by 4 publications

References 51 publications

The usefulness of leptin measurements and ultrasound fat thickness for assessment of body fat reserves of Awassi lambs

The usefulness of leptin measurements and ultrasound fat thickness for assessment of body fat reserves of Awassi lambs

Use of rapid immunochromatographic tests and PCR for the detection of vaccine viruses (CPV, CDV CAV) in faeces and conjunctival sac swabs of vaccinated dogs

Associations of feed efficiency with circulating IGF-1 and leptin, carcass traits and meat quality of lambs

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