Relationships between severity of signs and symptoms and quality of life in patients with chronic venous disease

Abstract

BACKGROUND: Chronic venous disease (CVD) is progressive and has a high prevalence in the economically active population. Its impact on the quality of life of affected individuals is poorly understood. OBJECTIVE: To test for correlations between the CEAP classification of CVD severity and CVD symptoms and quality of life of affected individuals. METHODS: We investigated 91 lower limbs in 59 patients with CVD (CEAP C1- C6). Patients were assessed with a Visual Analogue Pain Scale (VAPS), the Venous Clinical Severity Score (VCSS) and the SF-36 quality-of-life questionnaire. Spearman correlation coefficients were calculated. RESULTS: There were positive correlations between the CEAP classification and scores for VAPS (0.815, p <0.000), VCSS (0.937, p <0.000), and SF-36 in the dimensions Physical Functioning: -0.791, p <0.000; Role Physical: -0.839; p <0.000; Bodily Pain: -0.684; General Health: -0.617, p <0.000; Role Emotional: -0.691, p <0.000). There was no correlation with Vitality: -0.003, p=0.979; Role Social: -0.188, p=0.740 or Mental Health: -0.085, p=0.421. CONCLUSIONS: There were positive correlations between CEAP and both VAPS and VCSS. Chronic Venous Insufficiency progressively affects quality of life (SF-36). Physical and emotional aspects are more severe at later stages of CVD. Vitality, Mental Health and Role Social can be negatively impacted from the early stages of the disease.

Quality of life and associated factors in patients with lower limb chronic venous insufficiency

“…Consistent with these studies, we also found that patients with higher CEAP grade (C3-C4-C6) had lower mental health and QoL score compared with patients with less severe disease (C1-C2). Our study did not find any association between disease severity with physical functioning score, may be because more than half of our patients had grade 1 disease while according to Rossi [17] , in early stages, the disease mainly affects mental health. The later the stage, the more reduced the physical functioning, the more affected the work, everyday life activities, and family-social relationships.…”

Application of correlation analysis in cytology: Opportunities to study specific activity of follicular thyrocytes

“…The task of the correlation analysis method is to determine correlations between the studied parameters, the nature and pronouncement of which are established by the pair correlation coefficient (Akoglu, 2018;Schober et al, 2018;Uurtio et al, 2018). Prolonged use of the method facilitated the data accumulation for studying various biomedical processes (Miot, 2017(Miot, , 2018Yadav, 2018) at their multiple levels (Rossi et al, 2015;Maranzatto et al, 2016;Kim et al, 2017), which resulted in the development of tools to facilitate visualization, analysis and interpretation of the information obtained (Mutwil et al, 2010;Batushansky et al, 2016). However, the method is not intended to work with qualitative or binary data on the state of a studied biosystem.…”

Prevalência clínica-epidemiológica dos pacientes cirúrgicos de varizes em membros inferiores

“…Em razão da ineficácia das ações de redução de morbi-mortalidade e ausência da repercussão dos benefícios dos cuidados de saúde, na manifestação da Doença Venosa Crônica (DVC), a busca pelo conhecimento científico e clínico da doença, e de seus fatores associados, tem aumentado de forma significativa no Brasil (7) . Tais ações teriam o intuito de redução dos gastos, provenientes do tratamento dessa patologia, e diminuição da incidência das suas formas graves, por meio de uma avaliação precoce e eficiente.…”

“…Outro aspecto relevante é que, embora seja uma realidade mundial, o aumento da prevalência e da gravidade da DVC, estudos a respeito da intensidade dos sintomas e do comprometimento à qualidade de vida dos indivíduos, acometidos pela DVC, ainda são escassos (3,5,7) . Ademais, apesar de estudos apontarem que o uso de um questionário validado como VEINES QoL/Sym ® possibilita um maior conhecimento da qualidade de vida do individuo com IVC e de seu impacto funcional, psicológico e social (4,6) ,poucos estudos confrontam a gravidade dos sinais clínicos e o desenvolvimento da doença do indivíduo, atingido por essa patologia (4,6) .…”