Relationships between thyroid hormones and serum energy metabolites with different patterns of postpartum luteal activity in high-producing dairy cows

Kafi, M.; Tamadon, Amin; Saeb, M.; Mirzaei, Abdolah; Ansari-Lari, Maryam

doi:10.1017/s1751731112000043

Cited by 18 publications

(13 citation statements)

References 42 publications

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“…Furthermore, energy balance can also play a major role in affecting the decrease in plasma thyroid hormone (TH) levels in small ruminants [34], thus signifying the importance of the optimum nutrition for maintaining appropriate thyroid hormone levels in sheep. Consistent with this notion, plasma thyroid hormone concentrations are correlated with feed intake in several ruminant species [34,35]. In addition, thyroid hormones decide the metabolic activity, and such metabolic activity are drastically affected by nutritional stress [19,34].…”

Section: Discussionmentioning

confidence: 67%

Effect of Different Diet Level on the Physiological Adaptability, Biochemical and Endocrine Responses and Relative Hepatic HSP70 and HSP90 Genes Expression in Osmanabadi Kids

Sejian¹,

Bagath²,

Parthipan³

et al. 2015

JAST-A

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Abstract:The study was conducted to investigate the impact of different levels of feed on the adaptive capability based on physiological, blood biochemical, endocrine and molecular mechanisms in growing Osmanabadi kids. The primary objective of the study was to identify if HSP70 and HSP90 can be a nutritional stress marker for goat. The study was conducted for a period of two months. The animals were randomly divided into three groups as GI (n = 6; ad libitum feeding), GII (n = 6; 20% less than ad libitum) and GIII (n = 6; 40% less than ad libitum). The animals were fed with feed consisting of 50% roughage and 50% concentrate. Blood collection was carried out at fortnightly intervals. Body weights were recorded at weekly interval. Physiological responses, biochemical responses, plasma tri-iodo-thyronine (T 3 ), thyroxin (T 4 ) and cortisol were recorded at fortnightly interval. At the end of study period, only GI and GIII animals were slaughtered and different organs were collected for histopathological studies as well as for hepatic HSP70 and HSP90 mRNA transcript expression. Body weight recorded showed significant (P < 0.01) differences between the groups. Physiological responses showed significant (P < 0.01) variation among the groups. Among the biochemical parameters, plasma glucose and total plasma protein and globulin showed significant (P < 0.01) differences between the groups. Plasma T3 (P < 0.01), T4 (P < 0.01) and cortisol (P < 0.05) also differed significantly between the groups. The relative hepatic HSP70 mRNA transcript expression was significantly (P < 0.05) higher in GIII (2.8 fold) as compared to GI (1 fold) kids. Similar result was obtained for hepatic HSP90 mRNA transcript expression. From the results, it can be concluded that Osmanabadi kids possessed the ability to alter their adaptive mechanisms to maintain homeostasis. Further, the study revealed the significance of providing the optimum nutrition for these animals to adapt to existing environmental conditions. The study also established that respiration rate (RR), rectal temperature (RT), T 3 , T 4 and cortisol are considered as nutritional stress markers for goat. Further, the results revealed that probably this is the first study to establish the nutritional stress impact on heat shock protein (HSP) expression in goats. The study identified both HSP70 and HSP90 to be the ideal molecular markers for feed deficit in goats.

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Section: Discussionmentioning

confidence: 67%

Effect of Different Diet Level on the Physiological Adaptability, Biochemical and Endocrine Responses and Relative Hepatic HSP70 and HSP90 Genes Expression in Osmanabadi Kids

Sejian¹,

Bagath²,

Parthipan³

et al. 2015

JAST-A

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“…Eurthermore, energy balance can also play a major role in affecting the decrease in plasma TH levels in small mminants (Kong et al, 2004), thus signifying the importance of optimum nutrition for maintaining appropriate thyroid hormone levels in sheep (Todini, 2007). Consistent with this notion, plasma thyroid hormone concentrations are correlated with feed intake in several mminant species (Kong et al, 2004;Kafi et al, 2012). In addition, thyroid hormones decide the metabolic activity; metabolic activity is also drastically affected by nutritional stress.…”

Section: Discussionmentioning

confidence: 80%

“…Genetic and environmental factors are largely translated into hormonal signals affecting growth processes involving a complex sequence of interactions between different hormones (Kong et al, 2004;Todini, 2007;Kafi et al, 2012). The somatotrophic (growth hormone, GH; growth hormone receptor, GHR; insulin-like growth factor, IGF-1) axis is considered to be one of the most important among them, because of their broad range of effects and central role in growth (Thom et al, 2006;Funston et al, 2010;Jaquiery et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Effect of nutritional restriction on growth, adaptation physiology and estrous responses in Malpura ewes

2014

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The study was conducted to ascertain the effects of nutritional restrictions on growth, physiological adaptability and reproduction in sheep. The experiment was conducted for a period of 35 days covering two estrus cycles in 40 adult Malpura ewes. The animals were randomly divided into four groups of 10 animals each (100%; 80%; 70%; 60% of ad libitum). The ewes were fed a ration consisting of 70% roughage and 30% concentrate. At weekly intervals, physiological responses were recorded and blood samples were also collected. Nutritional restriction of different magnitude (80%; 70%; 60% of ad libitum) altered the growth, physiological adaptability and estrus responses to different extents in Malpura ewes. But the impact was most severe in 60% of ad libitum group. Nutritional restriction to the level of 60% of ad libitum feeding significantly decreased body weight, body eondition score, plasma insulin-like growth factor, pulse rate in the morning, respiration rate and pulse rate in the afternoon, plasma glucose, total protein, albumin, total cholesterol, plasma tri-iodo-thyronine and thyroxine, plasma cortisol, plasma estradiol, estrus % and estrus duration, while it significantly increased plasma concentration of growth hormone, hemoglobin, plasma concentration of progesterone and estrus cycle length. The study clearly establishes the effect of different levels of nutrition and its impact on the biological functions necessary to adapt to semi-arid environment. Although, 80%, 70% and 60% groups showed signs of nutritional stress, the effects were more pronounced in 60% ewes. Furthermore, this study clearly establishes the role of various hormones required to adapt to different levels of nutritional stress in Malpura ewes.

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“…This is similar to the observations by Antaya et al (2015) who also did not find changes in the thyroid hormones after supplementation with kelp. However, although the concentrations were generally within the normal range for cattle (Kafi et al, 2012), the free T3 was above the reference range (2.0-3.0 pmol/L) already at the first sampling and may be particularly influenced by the nutritional iodine intake (Ong et al, 2014). Whether this had clinical implications is not clear because we did not specifically assess the thyroid glands.…”

Section: Short Communicationmentioning

confidence: 82%

Short communication: Iodine concentrations in serum, milk, and tears after feeding Ascophyllum nodosum to dairy cows—A pilot study

Sorge

Henriksen

Baştan

et al. 2016

Journal of Dairy Science

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Kelp (Ascophyllum nodosum) is rich in iodine and often fed by organic dairy producers as a mineral supplement to support animal health. A commonly held belief is that kelp supplementation decreases susceptibility to infectious bovine keratoconjunctivitis due to increased iodine concentrations in tears. Whereas serum and milk iodine concentrations are positively correlated and modulated by oral iodine supplementation, nothing is known about the iodine concentration of tears. Therefore, the 3 objectives of this pilot study were to determine (1) the iodine content of tears, milk, and serum of cows after being fed kelp for 30d; (2) the trace mineral and thyroid status of cows before (d 0) and after being fed kelp for 30d; and (3) the in vitro growth rate of bacteria in tears (Moraxella bovis) or milk (Staphylococcus aureus, Escherichia coli, Streptococcus uberis) collected from cows fed no kelp (d 0) or kelp (d 30). Cows (n=3/treatment) were individually fed 56g of kelp per day (n=3/treatment) or not (n=3/no treatment) for 30 d. Daily feed intake of the TMR was recorded and weekly TMR, kelp, milk, blood and tear samples were collected and analyzed for iodine. The feed samples were pooled and further analyzed for other minerals. On d 0 and 30, liver biopsies and blood samples were collected and analyzed for mineral content and thyroid hormone concentrations, respectively. An inhibition test used milk and tear-soaked plates from kelp-fed cows (d 0 and 30) as well as 1 and 7.5% iodine as positive and distilled water as negative control. As expected, serum iodine concentrations were positively correlated with milk and tear iodine concentrations. Whereas the iodine concentrations in serum increased significantly in the kelp-fed cows during the 30-d study, milk and tear iodine concentrations increased only numerically in these cows compared with the control group. Liver mineral profiles were comparable between groups and generally did not change over the course of the study. Thyroid hormones remained overall within the reference range throughout the trial. Neither milk nor tears from kelp-fed cows inhibited in vitro growth of any of the plated bacteria. In summary, serum iodine concentration was correlated with the iodine concentration in milk and tears and feeding kelp increased only the serum iodine levels of cows in this trial. Bacterial growth was not inhibited in milk and tears of kelp-fed cattle in vitro, and prevention of infectious bovine keratoconjunctivitis would not be based solely on increased iodine concentrations in tears.

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Relationships between thyroid hormones and serum energy metabolites with different patterns of postpartum luteal activity in high-producing dairy cows

Cited by 18 publications

References 42 publications

Effect of Different Diet Level on the Physiological Adaptability, Biochemical and Endocrine Responses and Relative Hepatic HSP70 and HSP90 Genes Expression in Osmanabadi Kids

Effect of Different Diet Level on the Physiological Adaptability, Biochemical and Endocrine Responses and Relative Hepatic HSP70 and HSP90 Genes Expression in Osmanabadi Kids

Effect of nutritional restriction on growth, adaptation physiology and estrous responses in Malpura ewes

Short communication: Iodine concentrations in serum, milk, and tears after feeding Ascophyllum nodosum to dairy cows—A pilot study

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