Relationships of Illness Perceptions with Depression and Anxiety in People Who Live with HIV/AIDS in a High-prevalence Ethnic Autonomous Region of Sichuan, China

Feng, Chuanteng; Yu, Bin; Fu, Yao; Reinhardt, Jan D.

doi:10.1007/s10461-022-03707-4

Cited by 5 publications

(2 citation statements)

References 45 publications

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“…In HIV/AIDS-related research, stigmatization, discrimination, and privacy concerns may contribute to high loss to follow-up rates. For example, researchers may encounter di culties in contacting participants or participants refusing to continue participating [59][60]. Similarly, the length of follow-up time may also be in uenced by issues such as research budgets and participant retention, explaining why there are more studies with shorter follow-up periods and insu cient attention to long-term effects [61].…”

Section: Status Of Follow-up Studies and Long-term Interventionsmentioning

confidence: 99%

HIV Peer Education Interventions：An Evidence Map

Zeng,

Wan,

Zhao

et al. 2023

Preprint

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Objective: This study aims to apply the evidence mapping method to systematically retrieve and summarize the clinical research literature on HIV peer education interventions to understand the distribution of evidence in this field. Methods: We conducted literature searches on the Chinese Biomedical Literature Database, Wanfang Database, CNKI, VIP Database, PubMed, Web of Science, CINAHL, EMBASE, and Cochrane Library, focusing on clinical randomized controlled trials (RCTs), nonrandomized controlled trials (prospective and retrospective cohort studies), and systematic reviews/meta-analyses of HIV peer education interventions. Two independent reviewers screened the included papers, extracted data, and assessed the quality of the included studies. Results: A total of 156 articles were included in this study. We analyzed the annual publication trends, study types, study sizes, and distribution of the clinical research. We also examined the methodological quality and conclusions of the systematic reviews, the distribution of study populations, follow-up and intervention durations in the included studies, the methods used in the intervention and control groups, and the outcome measures of the included studies. Conclusion: Currently, there is a lack of evidence in HIV peer education intervention research, specifically in terms of prospective and case‒control studies, studies targeting healthcare workers as the study population, long-term interventions and follow-ups, and mixed-method peer education intervention studies. The quality of clinical research design and systematic reviews needs improvement. Patient or Public Contribution： The first analysis of HIV peer education intervention studies using evidence maps found strengths in the field and a small number of high -quality systematic reviews/meta-analyses showing the effectiveness of interventions. We found that there is currently less evidence for cohort studies as well as case‒control studies, studies targeting health care workers as subjects, long-term interventions, and long-term follow-up, multivariate mixed peer education intervention studies in HIV peer education intervention research, and the quality of clinical study design and systematic evaluation needs to be improved. More high-quality studies are needed to confirm the effectiveness of HIV peer education interventions.

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Section: Status Of Follow-up Studies and Long-term Interventionsmentioning

confidence: 99%

HIV Peer Education Interventions：An Evidence Map

Zeng,

Wan,

Zhao

et al. 2023

Preprint

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“…Among these factors, mental health symptoms are a modifiable risk factor for early intervention of HAND [9][10][11][12]. Furthermore, aging PLWH may suffer from mental health symptoms more than general aging people due to negative illness perception [13][14][15], which may further affect cognition-related behavior such as non-adherence to ART [16,17]. Therefore, addressing mental health symptoms in this vulnerable population may benefit cognitive function.…”

Section: Introductionmentioning

confidence: 99%

Exploring Interrelationships between Mental Health Symptoms and Cognitive Impairment in Aging People Living with HIV in China

Ma,

Yu,

Fan

et al. 2024

Dement Geriatr Cogn Disord

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Introduction: Mental health symptoms and cognitive impairment are highly prevalent and intertwined among aging people living with HIV (PLWH). This study aimed to assess the interrelationships and strength of connections between individual mental health symptoms and cognitive impairment. It sought to identify specific symptoms linking mental health and cognitive impairment in aging PLWH. Methods: Participants in Sichuan Older People with HIV Infections Cohort Study (SOHICS) were recruited between November 2018 and April 2021 in China. Mental health symptoms, including depression and anxiety, were assessed by the Patient Health Questionnaire (PHQ-9) and General Anxiety Disorder-7 (GAD-7), respectively. Cognitive impairment was assessed by the Montreal Cognitive Assessment-Basic (MoCA-B). Partial correlation network was used to depict the interrelationships between mental health symptoms and cognitive impairment, and bridge strength was used to identify specific symptoms linking mental health and cognitive impairment. Results: Of the 1,587 recruited participants with a mean age of 63.0 years old, 47.0% had mild or severe cognitive impairment. Network analysis revealed that cognitive function, visual perception, and problem-solving task of the MoCA-B were negatively correlated with appetite, energy, and motor of the PHQ-9, respectively. Based on their interrelationships, problem-solving task and motor acted as bridge symptoms. Conclusion: Problem-solving task and motor may be potential intervention targets to reduce the overall risk of mental health symptoms and cognitive impairment. Future research could assess the feasibility and effectiveness of specific interventions designed to the two symptoms in aging PLWH.

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