Relationships of linear and nonlinear ultrasound parameters with porosity and trabecular spacing in trabecular-bone-mimicking phantoms

Lee, Kang Il

doi:10.1121/1.4972530

Cited by 9 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Correlation coefficients of B/A with apparent bone density (r = 0.95), BMD (r = 0.77), BV/TV (r = 0.80), and Tb.Th (r = 0.44) have been reported in bovine cancellous femur (0.5 MHz transmitter, 0.5 or 1 MHz receiver) [366][367][368]. Similar findings have been reported in aluminum-foam cancellous-bone-mimicking phantoms [328].…”

Section: F Nonlinear Properties Of Cancellous Bonesupporting

confidence: 78%

“…19) can exhibit slow wave phase velocity consistent with Biot theory [325][326][327]. A study on one set of aluminum foams indicates that SOS increases with porosity, but nBUA decreases with porosity [328]. Studies on nickel foams [329] and copper foams [330] indicate several properties that are consistent with cancellous bone: attenuation coefficient varies approximately as frequency to the first power [1], phase velocity exhibits negative dispersion [21,105,[148][149][150], and backscatter coefficient varies approximately as frequency cubed [274,275].…”

Section: Cancellous Bone-mimicking Phantomsmentioning

confidence: 57%

See 1 more Smart Citation

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Wear

2020

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

View full text Add to dashboard Cite

Ultrasound is now a clinically-accepted modality in the management of osteoporosis. The most common commercial clinical devices assess fracture risk from measurements of attenuation and sound speed in cancellous bone. This review discusses fundamental mechanisms underlying the interaction between ultrasound and cancellous bone. Because of its two-phase structure (mineralized trabecular network embedded in soft tissue-marrow), its anisotropy, and its inhomogeneity, cancellous bone is more difficult to characterize than most soft tissues. Experimental data for the dependences of attenuation, sound speed, dispersion, and scattering on ultrasound frequency, bone mineral density, composition, microstructure, and mechanical properties are presented. The relative roles of absorption, scattering, and phase cancellation in determining attenuation measurements in vitro and in vivo are delineated. Common speed of sound metrics, which entail measurements of transit times of pulse leading edges (to avoid multipath interference), are greatly influenced by attenuation, dispersion, and system properties including center frequency and bandwidth. However, a theoretical model has been shown to be effective for correction for these confounding factors in vitro and in vivo. Theoretical and phantom models are presented to elucidate why cancellous bone exhibits negative dispersion, unlike soft tissue, which exhibits positive dispersion. Signal processing methods are presented for separating "fast" and "slow" waves (predicted by poro-elasticity theory and supported in cancellous bone) even when the two waves overlap in time and frequency domains. Models to explain dependences of scattering on frequency and mean trabecular thickness are presented and compared with measurements. Anisotropy, the effect of the fluid filler medium (marrow in vivo or water in vitro), phantoms, computational modeling of ultrasound propagation, acoustic microscopy, and nonlinear properties in cancellous bone are also discussed.

show abstract

Section: F Nonlinear Properties Of Cancellous Bonesupporting

confidence: 78%

Section: Cancellous Bone-mimicking Phantomsmentioning

confidence: 57%

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Wear

2020

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

View full text Add to dashboard Cite

show abstract

“…The opposite happens to the increasing trend of AIslow for parallel orientation versus porosity which due to the slow wave propagates through pore part of porous structure. When trabecular spacing and pore size growth, it boosts the flow of the fluid, which reduces the opposition of wave propagation, resulting in decreasing of the attenuation effect [24]. Previous research by Hosokawa et al [10], Kawasaki et al [5] and Otani [6] also reported the same outcome for the slow wave.…”

Section: Correlation Of the Wave Parameters With Various Porosities Amentioning

confidence: 70%

Incident and reflected two waves correlation with cancellous bone structure

et al. 2020

View full text Add to dashboard Cite

The correlation in bone microstructure for ultrasound pulse echo technique is still less accurate compared to through transmission technique. Previous works demonstrated, reflected two modes wave has significant association with bone porosity. The paper aims is to conduct simulation using pulse echo technique to examine the relationship between fast and slow waves with porosity of 2-dimensional cancellous bone models by comparing the result to through transmission technique. The "incident" and "reflected" waves were separated using bandlimited deconvolution method by estimating time threshold of fast and slow waves' transfer function. The parameters of the waves were computed, plotted versus porosity for six different thicknesses and the correlation coefficients between them were compared. The incident and reflected fast wave attenuations show marginally significant correlation with porosity for both bone models orientations. Wave propagation for parallel orientation dominated by incident and reflected fast wave, meanwhile, perpendicular orientation dominated by incident slow wave. The thickness factor affected wave amplitude but less affected the attenuation. Because of propagation loss, reflected wave shows lower correlation to porosity compared to incident wave. Hence, analyzing fast and slow waves might improve the measurement accuracy of pulse echo technique compared to using single mode wave to estimate bone quality.

show abstract

“…Thus, the selection of ROI, SOI and AR p-order should be carefully studied in vivo. Although BV/TV is one of the critical parameters to assess cancellous bones, previous studies have also reported the bone microstructures parameters, such as trabecular thickness, trabecular spacing, and porosity, have significant correlations with the ultrasonic backscatter parameters [64]- [67]. The correlations of these bone parameters with ultrasonic backscatter parameters were not addressed in this study and will be carried out in our future work.…”

Section: Limitationsmentioning

confidence: 81%

Effect of Spectral Estimation on Ultrasonic Backscatter Parameters in Measurements of Cancellous Bones

Liu

et al. 2019

IEEE Access

View full text Add to dashboard Cite

Relationships of linear and nonlinear ultrasound parameters with porosity and trabecular spacing in trabecular-bone-mimicking phantoms

Cited by 9 publications

References 20 publications

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Incident and reflected two waves correlation with cancellous bone structure

Effect of Spectral Estimation on Ultrasonic Backscatter Parameters in Measurements of Cancellous Bones

Contact Info

Product

Resources

About