2018
DOI: 10.1186/s13643-018-0760-3
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Relative frequency and risk factors for long-term opioid therapy following surgery and trauma among adults: a systematic review protocol

Abstract: BackgroundWhen patients have been on opioid therapy for more than 90 days, more than half of them continue using opioids years later. Knowing that long-term opioid consumption could lead to harmful side effects including misuse, abuse, and addiction, it is important to understand the risks of transitioning to prolonged opioid therapy to reduce its occurrence. Perioperative and trauma contexts are ideal models commonly used to study such transition. Long-term use of opioids might be associated with transformati… Show more

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Cited by 15 publications
(7 citation statements)
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“…The vast majority did not recall having received information about the addictive nature of opioids, the risk of withdrawal symptoms, or the need for a tapering plan. According to the literature, more than half of trauma patients receive an opioid prescription upon hospital discharge [ 19 , 42 ]. This may already introduce a risk of dependence, because opioid tolerance can develop within only a few weeks of continued use [ 43 ].…”
Section: Discussionmentioning
confidence: 99%
“…The vast majority did not recall having received information about the addictive nature of opioids, the risk of withdrawal symptoms, or the need for a tapering plan. According to the literature, more than half of trauma patients receive an opioid prescription upon hospital discharge [ 19 , 42 ]. This may already introduce a risk of dependence, because opioid tolerance can develop within only a few weeks of continued use [ 43 ].…”
Section: Discussionmentioning
confidence: 99%
“…In addition, consistent with previous research on “chronic opioid use” and to help ensure that the prescription opioid(s) were prescribed for OA (as opposed to short-term, acute pain), patients were required to have at least 90 days of cumulative supply of opioids during the follow-up period. 12 , 15 Finally, patients were divided into 2 mutually exclusive cohorts based on the index drug: Patients initiated on tramadol or a nontramadol opioid.…”
Section: Methodsmentioning
confidence: 99%
“…The vast majority did not recall having received information about the addictive nature of opioids, the risk of withdrawal symptoms, or the need for a tapering plan. According to the literature, more than half of trauma patients receive an opioid prescription upon hospital discharge (19,41). This may already introduce a risk of dependence, because opioid tolerance can develop within only a few weeks of continued use (42).…”
Section: Lack Of a Tapering Planmentioning
confidence: 99%