Relative Prevalence of Contact Allergens in North America in 2018

Scheman, Andrew; Patel, Kevin R.; Roszko, Karolina; Severson, David L.; Brod, Bruce A.; Jacob, Sharon E.; Lloyd, Rita; Nedorost, Susan T.; Watsky, Kalman L.; West, Dennis P.

doi:10.1097/der.0000000000000521

Cited by 12 publications

(4 citation statements)

References 23 publications

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“…Abbreviation: NPCP, natural personal care product. a The 100 most prevalent causes of acute contact dermatitis …”

Section: Resultsmentioning

confidence: 99%

“…Abbreviations: BHT, butylated hydroxytoluene; DEA, diethanolamine; DMDM, 1,3-dimethylol-5, 5-dimethyl; MCI, methylchloroisothiazolinone; MIT, methylisothiazolinone; NA, not applicable; NPCPs, natural personal care products. a Seventy-three unique allergens were identified; the table includes 43 that were among the 100 most clinically prevalent sources of allergic contact dermatitis and 4 (cetyl alcohol, stearyl alcohol, Lyral, and BHA) that are clinically prevalent but were not among the top 100. b Based on data from Scheman et al c Commonly used as fragrance. d Clinical prevalence ranks shown are for closely related substances that would elicit a positive reaction: cetyl alcohol and stearyl alcohol (not ranked among the 100 most clinically prevalent allergens) test positive to cetylstearyl alcohol; eugenol is found in fragrance mix; hexyl cinnamal and cinnamic alcohol are common components of Balsam of Peru; and MCI cross-reacts with MIT. e Lanolin, lanolin alcohol, and wool alcohol. f Tocopherol and vitamin E. g Clinically prevalent but not among the 100 most clinically prevalent allergens. h Lyral and hydroxyisohexyl 3-cyclohexene carboxaldehyde.…”

Section: Methodsmentioning

confidence: 99%

“… a Seventy-three unique allergens were identified; the table includes 43 that were among the 100 most clinically prevalent sources of allergic contact dermatitis and 4 (cetyl alcohol, stearyl alcohol, Lyral, and BHA) that are clinically prevalent but were not among the top 100.…”

Section: Methodsmentioning

confidence: 99%

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Prevalence of Contact Allergens in Natural Skin Care Products From US Commercial Retailers

2022

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“…Abbreviation: NPCP, natural personal care product. a The 100 most prevalent causes of acute contact dermatitis …”

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Prevalence of Contact Allergens in Natural Skin Care Products From US Commercial Retailers

2022

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“…Through inhalation exposure, nickel toxicity particularly puts the lungs and brain at risk [39,40]. Dermal contact with Ni can also cause dermatitis and other skin allergies [41,42]. According to Hauptman et al (1993) [43], ocular exposure to Ni 2+ causes lesions and retinal malformations in Xenopus embryos.…”

Section: Introductionmentioning

confidence: 99%

Metal accumulation in muscle and oxidative stress response in the liver of juvenile Oreochromis niloticus from contaminated sediment under a simulation of increasing temperature

Ihunwo

Ibezim-Ezeani

2022

Environ. Res. Commun.

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In the present study, a mesocosm experiment with contaminated sediment and clean groundwater using juvenile Oreochromis niloticus was set up to assess the effect of increasing temperature on bioaccumulation of metal in fish muscles (cadmium, chromium, nickel, and lead) and enzymatic activities in fish liver [reduced glutathione (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione transferase (GST), and glutathione peroxidase (GSH Px)]. The trend of temperature variation was Control 1 (0 Watts) < 60 Watts < 100 Watts < Control 2 (200 Watts). After 72hrs, there was no observed mortality in Controls 1 and 2; however, the % Survival in 0 Watts reduced to 90.0 ± 4.0 %. Furthermore, 60, 100 and 200 Watts had lower rates of survival at 46.0 ± 6.9, 36.0 ± 13.1, and 24.0 ± 11.1 % respectively. The calculated bioaccumulation factors (BAFs) for metals was in the trend: Pb > Cd > Cr > Ni. Mean metal pollution index (MPI) in fish muscles was lowest at 0 watts (24hrs - 7.86 ± 1.72, 72hrs - 25.77 ± 4.56) and highest at 100 watts (24hrs - 39.45 ± 1.91, 72hrs - 55.82 ± 1.05). Controls 1 and 2 showed no significant difference in the concentration of GSH and GR while showing a significant difference in GST and GSH Px concentrations after 24 and 72 hrs. Pearson’s correlation showed that GSH was inhibited by water temperature and, Cd, Cr, and Pb concentrations in surface water and fish. Therefore, an increase in ambient temperature in an already contaminated environment will increase the bioavailability of metal contaminants leading to an increase in bioaccumulation and exacerbation of oxidative stress in juvenile tilapia.

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Contact Dermatitis

Ruëff¹

2021

Braun-Falco´s Dermatology

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Relative Prevalence of Contact Allergens in North America in 2018

Cited by 12 publications

References 23 publications

Prevalence of Contact Allergens in Natural Skin Care Products From US Commercial Retailers

Prevalence of Contact Allergens in Natural Skin Care Products From US Commercial Retailers

Metal accumulation in muscle and oxidative stress response in the liver of juvenile Oreochromis niloticus from contaminated sediment under a simulation of increasing temperature

Contact Dermatitis

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