Relative superiority of the Lund–Malmö revised equation for glomerular filtration rate estimation in patients with end-stage renal disease not on dialysis among 23 equations

Abstract

The glomerular filtration rate (GFR) is an important index of the proper function of the kidneys, and measuring it precisely is indispensable for efficiently managing patients in the clinic. There exist several methods of how to estimate the GFR. However, studies evaluating the estimated GFR in patients with end-stage renal disease (ESRD) not on dialysis remain scarce. Our work sought to characterize a relative accurate equation for estimating kidney function in patients with ESRD who were not on dialysis. In contrast to prior studies assessing the GFR using less than 10 equations, we challenged 23 equations with our datasets. Among all the tested equations, the Lund-Malmö revised equation showed a low bias, a high precision and the highest accuracy in estimating the GFR in patients with ESRD not on dialysis.