Release of Antioxidant Compounds of Zingiber officinale by Ultrasound-Assisted Aqueous Extraction and Evaluation of Their In Vitro Bioaccessibility

Castañeda‐Ovando, Araceli; Jaimez-Ordaz, Judith; Cruz-Cansino, Nelly del Socorro; González-Olivares, Luis Guillermo; Rodríguez-Martínez, José Sergio

doi:10.3390/app10144987

Cited by 11 publications

(10 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contrary to past research, lemon did not produce high antioxidant activity or a high phenolic compound content. For antioxidant assays that are predicated on the antioxidants donating hydrogen to reduce the free radical, the amount of phenolic antioxidants will be correlated with the amount of antioxidant activity, thus, the lower the phenolic content, the more likely it is that the antioxidant capacity of that sample will be lower [52]. Since mint displayed the highest antioxidant activity for most assays, the antioxidant activity in GLMT may be contributed predominantly by mint's polyphenols or other phytochemicals.…”

Section: Phenolic Compound Estimation (Tfc Tpc and Ttc)mentioning

confidence: 99%

LC-ESI-QTOF-MS/MS Characterisation of Phenolics in Herbal Tea Infusion and Their Antioxidant Potential

et al. 2021

View full text Add to dashboard Cite

Ginger (Zingiber officinale R.), lemon (Citrus limon L.) and mint (Mentha sp.) are commonly consumed medicinal plants that have been of interest due to their health benefits and purported antioxidant capacities. This study was conducted on the premise that no previous study has been performed to elucidate the antioxidant and phenolic profile of the ginger, lemon and mint herbal tea infusion (GLMT). The aim of the study was to investigate and characterise the phenolic contents of ginger, lemon, mint and GLMT, as well as determine their antioxidant potential. Mint recorded the highest total phenolic content, TPC (14.35 ± 0.19 mg gallic acid equivalent/g) and 2,2′-azino-bis(3-e-thylbenzothiazoline-6-sulfonic acid), ABTS (24.25 ± 2.18 mg ascorbic acid equivalent/g) antioxidant activity. GLMT recorded the highest antioxidant activity in the reducing power assay, RPA (1.01 ± 0.04 mg ascorbic acid equivalent/g) and hydroxyl radical scavenging assay, •OH-RSA (0.77 ± 0.08 mg ascorbic acid equivalent/g). Correlation analysis showed that phenolic content positively correlated with the antioxidant activity. Venn diagram analysis revealed that mint contained a high proportion of exclusive phenolic compounds. Liquid chromatography coupled with electrospray ionisation and quadrupole time of flight tandem mass spectrometry (LC-ESI-QTOF-MS/MS) characterised a total of 73 phenolic compounds, out of which 11, 31 and 49 were found in ginger, lemon and mint respectively. These characterised phenolic compounds include phenolic acids (24), flavonoids (35), other phenolic compounds (9), lignans (4) and stilbene (1). High-performance liquid chromatography photometric diode array (HPLC-PDA) quantification showed that GLMT does contain a relatively high concentration of phenolic compounds. This study presented the phenolic profile and antioxidant potential of GLMT and its ingredients, which may increase the confidence in developing GLMT into functional food products or nutraceuticals.

show abstract

Section: Phenolic Compound Estimation (Tfc Tpc and Ttc)mentioning

confidence: 99%

LC-ESI-QTOF-MS/MS Characterisation of Phenolics in Herbal Tea Infusion and Their Antioxidant Potential

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The values of antioxidant capacity and total phenolics obtained for D. bicolor through a French press (434–2128 mg ET/100 g and 110–1920 mgEFe 2+ /100 g, 684–9929 mg EGA/100 g) are superior to those reported about the extraction of bioactive compounds from several vegetal matrixes including flowers [ 22 ], tea [ 36 ], medicinal and aromatic plants [ 23 , 27 , 30 , 38 ], and agri-food by-products [ 25 , 41 ]. Those studies include the use of different extraction methods (i.e., conventional, microwave, and ultrasound) and involve several extractant agents such as water, methanol, ethanol, acetone, ethyl acetate as well as their mixtures with water.…”

Section: Resultsmentioning

confidence: 64%

“…This is in agreement with data reported for antioxidants extracted from different vegetable matrixes [ 34 , 35 , 36 , 37 ]. Similarly, Contreras-López et al [ 38 ] used thermo-ultrasound, applying temperatures from 30 to near 60 °C to obtain the higher liberation of antioxidant and phenolic compounds from ginger ( Zingiber officinalis ). In our research, it was also observed that the best results were obtained by using times of extraction no longer than 15 min.…”

Section: Resultsmentioning

confidence: 99%

Comparative Evaluation of Four Extraction Methods of Antioxidant Compounds from Decatropis bicolor in Aqueous Medium Applying Response Surface Design

et al. 2021

Self Cite

View full text Add to dashboard Cite

The objective of this paper is to compare conventional, ultrasound, microwave, and French press methods for the extraction of antioxidant compounds from Decatropis bicolor in an aqueous medium. This plant is widely used in Mexican traditional medicine for breast cancer treatment. Despite that, there are few studies on D. bicolor. Two response surface designs were applied to establish the best conditions of the liberation of antioxidants from D. bicolor, which were determined by DPPH• and Ferric Reducing Antioxidant Power (FRAP) techniques. The total phenolic content was evaluated by the Folin-Ciocalteu method. The results showed that D. bicolor is a source of antioxidants (669–2128 mg ET/100 g and 553–1920 mg EFe2+/100 g, respectively) and phenolic compounds (2232–9929 mg EGA/100 g). Among the physical factors that were analyzed, the temperature was the determinant factor to liberate the compounds of interest by using low concentrations of the sample and short times of extraction. The French press was the most efficient method, obtaining values of antioxidant activity and phenolic compounds even higher than those reported by using extraction methods with solvents such as methanol.

show abstract

“…Shan et al [63] have reported that a methanolic extract of dried ginger, did not possess a very high phenol content as compared to other spices (6.3 mg GAE/1 g of dry ginger). In a recent report by Contreras-López et al [38], which involved the ultrasound-assisted extraction of whole ginger rhizomes using water as solvent, the authors found low TPC values (ranging from 0.08 to 0.17 mg GAE/g of dry material) due to the effect of the ultrasonic energy which could promote side-reactions between the extracted phenolic compounds, which does not allow their efficient extraction in water.…”

Section: Total Phenolic Content Of the Ginger Extractsmentioning

confidence: 99%

“…To evaluate the use of ginger as a natural source of bioactive compounds, several studies have reported the various extraction methods using common VOCs, in various temperatures and extraction times [1,3,38,39]. However, to our knowledge, there is only one study by Hsieh et al [19] investigating the application of greener techniques such as UAE (using an ultrasonic bath) in combination with NaDESs as extraction media for the extraction of valuable compounds from dry ginger as well as for the optimization of the proposed method.…”

Section: Introductionmentioning

confidence: 99%

Natural Deep Eutectic Solvents (NaDESs) as Alternative Green Extraction Media for Ginger (Zingiber officinale Roscoe)

Tzani

Kalafateli

Tatsis

et al. 2021

Sustainable Chemistry

View full text Add to dashboard Cite

The extraction of valuable phytochemicals from natural sources is an important and constantly evolving research area. Zingiber officinale Roscoe (ginger) contains high amounts of bioactive phytochemicals, which are desirable due to their significant properties. In this work, the ability of different natural deep eutectic solvents (NaDESs) to serve as green solvents for the preparation of high added value extracts from ginger is explored, in combination with ultrasound assisted extraction. The method was optimized by applying a response surface methodology using the NaDES Bet/La/W (1:2:2.5). Three independent variables, namely the extraction time, ultrasound power and NaDES-to-dry-ginger ratio, were investigated by employing a 17-run three-level Box–Behnken Design (BBD) in order to study the correlation between the extraction conditions and the quality of the obtained extracts. The optimum conditions (in order to achieve simultaneously maximum total phenolic content and antioxidant activity), were found to be 23.8 min extraction time, 60 Watt and NaDES/ginger 25:1 w/w. In the optimum conditions the DPPH radical scavenging ability of the extracts was found to reach IC50 = 18.16 mg/mL after 120 min, whereas the TPC was 20.10 ± 0.26 mg GAE/g of dry ginger. The green methodology was also compared with the extraction using conventional solvents. All the obtained extracts were evaluated for their antioxidant activity and their total phenolic content, while the extract derived by the optimum extraction conditions was further investigated for its ability to bind to calf thymus DNA (ctDNA).

show abstract

Release of Antioxidant Compounds of Zingiber officinale by Ultrasound-Assisted Aqueous Extraction and Evaluation of Their In Vitro Bioaccessibility

Cited by 11 publications

References 46 publications

LC-ESI-QTOF-MS/MS Characterisation of Phenolics in Herbal Tea Infusion and Their Antioxidant Potential

LC-ESI-QTOF-MS/MS Characterisation of Phenolics in Herbal Tea Infusion and Their Antioxidant Potential

Comparative Evaluation of Four Extraction Methods of Antioxidant Compounds from Decatropis bicolor in Aqueous Medium Applying Response Surface Design

Natural Deep Eutectic Solvents (NaDESs) as Alternative Green Extraction Media for Ginger (Zingiber officinale Roscoe)

Contact Info

Product

Resources

About