Release of cervical muscular tension improved severe pruritus in moderate-to-severe atopic dermatitis: A case series

Hosono, Shusaku; Fujita, Koji; Nimura, Akimoto; Akita, Keiichi

doi:10.1016/j.jdcr.2020.03.018

Cited by 3 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies of the musculoskeletal system have also demonstrated that high levels of psychological stress can modulate the autonomic nervous system and induce increased muscle tension, especially neck stiffness [8]. Recently, Hosono et al reported that the release of cervical muscular tension in three cases of moderate-to-severe AD improved neck stiffness, severe pruritus, sleep disturbances, and atopic symptoms [9]. However, they evaluated only three cases, and psychological factors were not fully considered in the evaluations.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Release of Cervical Muscle Tension Improves Psychological Stress and Symptoms of Moderate-to-Severe Atopic Dermatitis: a Case Series with 20 Patients

Hosono

Fujita

Nimura

et al. 2022

Dermatol Ther (Heidelb)

Self Cite

View full text Add to dashboard Cite

Introduction: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease that is triggered by intense pruritus, impaired skin barrier function, and immune responses to allergenic substances. Break-through therapies for AD include molecular-targeted drugs and the effective management of severe symptoms of AD. However, patients with clinical improvements may continue scratching owing to the influence of psychological stress, which might lead to quick relapses of stressors and subsequent intensive scratching. New drugs may be ineffective because of such scratching behavior caused by stressors. Therefore, it may be useful to consider adjunctive treatment options that focus on external stressors as triggers of deterioration of AD. We hypothesized that improvement of psychological stress by relieving cervical muscle tension would reduce pruritus and atopic symptoms. Methods: Overall, 21 patients with moderateto-severe AD were treated to relieve cervical muscular tension using Spineliner SA201, which assists in osteopathic manipulative treatment. We assessed the subjective and objective symptoms of AD, cervical muscle tension, which was evaluated using cervical range of motion (ROM), and psychological burden. Only moisturizers were applied topically during the study period, and no topical corticosteroid therapy was used. Results: Twenty patients who completed the treatment demonstrated improvement in the symptoms of AD: changes on the visual analog scale (VAS) for pruritus were -44.2%, Eczema Area and Severity Index (EASI) was -67.9%, thymus and activation-regulated chemokine (TARC) was -56.2%, Hospital Anxiety and Depression Scale (HADS) was -27.2%, sleep disturbance was -49.7%, and Dermatology Life Quality Index (DLQI) was -46.7%. Additionally, the cervical muscle tension improved significantly: changes in cervical ROM were 14.7%. Conclusions: Release of cervical muscle tension may improve psychological stress and have an effect on moderate-to-severe AD.The manuscript was prepared according to the guidelines provided in the CONSORT guidelines.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Recently, Hosono et al. reported that the release of cervical muscular tension in three cases of moderate-to-severe AD improved neck stiffness, severe pruritus, sleep disturbances, and atopic symptoms [ 9 ]. However, they evaluated only three cases, and psychological factors were not fully considered in the evaluations.…”

Section: Introductionmentioning

confidence: 99%

Release of Cervical Muscle Tension Improves Psychological Stress and Symptoms of Moderate-to-Severe Atopic Dermatitis: a Case Series with 20 Patients

Hosono

Fujita

Nimura

et al. 2022

Dermatol Ther (Heidelb)

Self Cite

View full text Add to dashboard Cite

show abstract

“…OM might influence the neurovegetative system, 7 and there is limited evidence for possible benefits of OM in adults with AD. 8,9 The aim of this study was to determine the feasibility, exploratory effectiveness and cost-effectiveness of semistandardized ACU and OM treatments in adult patients with AD compared with a control group (CG), and to gather experience and data for planning future confirmatory trials.…”

Section: Introductionmentioning

confidence: 99%

“…OM is a diagnostic and therapeutic medical practice that applies manual treatment techniques. OM might influence the neurovegetative system, 7 and there is limited evidence for possible benefits of OM in adults with AD 8,9 …”

Section: Introductionmentioning

confidence: 99%

Acupuncture and osteopathic medicine for atopic dermatitis: a three-armed, randomized controlled explorative clinical trial

Rotter

Ahnert

Geue

et al. 2022

Clinical and Experimental Dermatology

View full text Add to dashboard Cite

Background. Patients with atopic dermatitis (AD) frequently use acupuncture (ACU) and osteopathic medicine (OM), although their therapeutic benefits are unclear. Aim. To investigate the effectiveness of ACU and OM in patients with AD. Methods. In a three-armed, single-centre, randomized controlled open explorative clinical trial, adult patients with AD received ACU, OM or no study intervention (control group; CG) plus routine care. Outcomes included disease severity (SCORing Atopic Dermatitis; SCORAD), itching intensity (visual analogue scale; VAS), frequency of topical corticosteroid (TCS) use over 7 days and cost-effectiveness. Endpoints were analysed by analysis of covariance adjusted for the respective baseline value and TCS use. Results. Overall, 121 patients (92 women, 29 men) with a mean AE SD age of 31.4 AE 10.5 years were randomized. After 12 weeks, the adjusted means (95% CI) for ACU, OM and control were, respectively,2) and 23.7 (19.9-27.5) for SCORAD (P = 0.32); 27.9 (19.5-36.4), 35.0 (26.9-43.0) and 42.3 (34.7-50.0) for VAS itching (P < 0.05); and 2.3 (0.8-3.9), 1.9 (0.4-3.5) and 4.3 (2.6-6.0), for TCS use (P = 0.10). ACU and OM were not cost-effective compared with the CG. Conclusion. Although no differences in disease severity were found, our findings indicate that ACU might reduce itching in patients with AD. Furthermore, ACU and OM showed a trend towards reducing TCS use.

show abstract

Akupunktur und osteopathische Medizin bei atopischer Dermatitis

Rotter¹,

Ahnert²,

Geue³

et al. 2023

Osteopathische Medizin

View full text Add to dashboard Cite

Release of cervical muscular tension improved severe pruritus in moderate-to-severe atopic dermatitis: A case series

Cited by 3 publications

References 13 publications

Release of Cervical Muscle Tension Improves Psychological Stress and Symptoms of Moderate-to-Severe Atopic Dermatitis: a Case Series with 20 Patients

Release of Cervical Muscle Tension Improves Psychological Stress and Symptoms of Moderate-to-Severe Atopic Dermatitis: a Case Series with 20 Patients

Acupuncture and osteopathic medicine for atopic dermatitis: a three-armed, randomized controlled explorative clinical trial

Akupunktur und osteopathische Medizin bei atopischer Dermatitis

Contact Info

Product

Resources

About