Benítez-Flores, S, de S. Castro, FA, Lusa Cadore, E, and Astorino, TA. Sprint interval training attenuates neuromuscular function and vagal reactivity compared with high-intensity functional training in real-world circumstances. J Strength Cond Res 37(5): 1070-1078, 2023-The aim of this study was to compare the acute cardiovascular and neuromuscular effects of 3 time-matched sessions of high-intensity training. Eighteen moderately active adults (9 women and 9 men [age: 23 6 2.9 years; maximum oxygen consumption (V Ȯ2 max): 47.6 6 4.1 ml•kg 21 •min 21 ]) performed three low-volume (;9 minutes) sessions in a randomized order: sprint interval training (SIT), burpee interval training (BIT) (10 3 5 seconds efforts 3 35 seconds recovery), and vigorous intensity continuous training (VICT) (6 minutes 5 seconds of running at ;85% of peak heart rate [HR peak ]). Indices related to heart rate (HR), neuromuscular performance (counter movement jump height [CMJ height ] and squat and bench press power), and autonomic balance (heart rate recovery and heart rate variability [HRR and HRV] )were monitored during exercise. Sprint interval training and VICT elicited a higher HR mean (171.3 6 8.4 and 166.5 6 7.5 vs. 150.5 6 13.6 b•min 21 , p , 0.001) and time of $90%HR peak (133.3 6 117.4 and 110 6 128.9 vs. 10 6 42.4 seconds, p , 0.01) than BIT. Sprint interval training exhibited a slower HRR and lower HRV than BIT and VICT (p , 0.05) postsession. Moreover, only SIT resulted in a significant decline (p , 0.01) in CMJ height (34.7 6 7.2 to 33.5 6 7.2 cm), relative squat mean power (25.5 6 4.5 to 23.8 6 4.9 W•kg 21 ), and relative bench press peak power (6.9 6 2.4 to 6.2 6 2.5 W•kg 21 ). Results revealed that SIT diminishes the sympathovagal reactivation and neuromuscular performance compared with work-matched BIT and VICT.