Reliability and Validity of the Ocular Surface Disease Index

Schiffman, Rhett M.; Christianson, Murray D.; Jacobsen, Gordon; Hirsch, J. E.; Reis, Brenda L.

doi:10.1001/archopht.118.5.615

Cited by 2,449 publications

(2,021 citation statements)

References 11 publications

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“…The score of the questionnaire ranges from 0 to 12 (no disability), to 13-22 (light dry eye), to 23-32 (moderate dry eye), to 33-100 (severe dry eye). 8 The Schirmer tests were performed as described elsewhere 7 by using sterile Schirmer strips (ContaCare Ophthalmic) without anaesthesia (Schirmer test I) or after application of oxybuprocain 0.5% (Jones test), in a room controlled for lighting (dim light room), temperature (20-221C), and humidity (40-60%). Abnormal value was regarded as r5 mm/wetting after 5 min 7 for Schirmer I, and o3 mm/wetting after 1 min for Jones test.…”

Section: Methodsmentioning

confidence: 99%

Diagnostic performance of tear function tests in Sjogren's syndrome patients

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Cellini

et al. 2006

Eye

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Objective To evaluate the diagnostic performance of the tests included in primary Sjogren's syndrome (SS-I) diagnostic criteria (Schirmer I, break-up time, vital dye staining) and to compare them with other examinations related to the ocular surface status. Methods Clinical and cytological data were collected from 177 patients (62 SS-1, 56 non-SS autoimmune diseases, 59 Sicca syndrome). Tear tests included: a validated questionnaire on symptoms, Schirmer I, Jones test, Ferning test, BUT, corneal aesthesiometry, tear clearance test, lissamine green staining, impression conjunctival cytology. Data were statistically evaluated and sensitivity, specificity, likelihood ratio (LR þ ), receiveroperating characteristics (ROC) curves were calculated for each test. Results Data showed a poor diagnostic performance of Schirmer test I (sensitivity 0.42; specificity 0.76; LR þ 1.75) and BUT (sensitivity 0.92; specificity 0.17; LR þ 1.11) (area under the curve in ROC analysis o0.58). Validated subjective symptoms questionnaire (sensitivity 0.89; specificity 0.72; LR þ 3.18), Jones test (sensitivity 0.60; specificity 0.88; LR þ 5), corneal aesthesiometry (sensitivity 0.80; specificity 0.67; LR þ 2.42), and tear clearance test (sensitivity 0.63; specificity 0.84; LR þ 3.93), all exhibited a high diagnostic performance (area under the curve in the ROC analysis always 40.70). Lissamine green staining exhibited the best performance (sensitivity 0.63; specificity 0.89; LR þ 5.72) but the result could be distorted by an incorporation bias. Conclusions Our data suggest to implement the items for ocular signs and symptoms contained in many SS-I diagnostic criteria with the use of a validated questionnaire, performance of Jones test, corneal aesthesiometry measurement, and tear clearance rate evaluation.

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Section: Methodsmentioning

confidence: 99%

Diagnostic performance of tear function tests in Sjogren's syndrome patients

Versura

Frigato

Cellini

et al. 2006

Eye

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“…The OSDI, developed by the Outcomes Research Group at Allergan Inc (Irvine, California), is a 12-item questionnaire designed to provide a rapid assessment of the symptoms of ocular irritation consistent with dry eye disease and their impact on visionrelated functioning. 6 Presence of symptoms during the last week is rated per item on a five-M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT 6 point scale (0-4) from 'none of the time' to 'all of the time'. The OSDI total score (ranging from 0-100) can be calculated with a formula that uses the sum score of all completed questions.…”

Section: Assessment Of Dry Eye Symptomsmentioning

confidence: 99%

“…In a similar way, scores from the 3 OSDI subscales (i) ocular symptoms, (ii) vision-related functions, and (iii) environmental triggers can be calculated by looking at questions 1-5, 6-9 and 10-12, respectively. 6 …”

Section: Assessment Of Dry Eye Symptomsmentioning

confidence: 99%

Sex differences in clinical characteristics of dry eye disease

et al. 2018

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Please cite this article as: Vehof J, Sillevis Smitt-Kamminga N, Nibourg SA, Hammond CJ, Sex differences in clinical characteristics of dry eye disease, Ocular Surface (2018), doi: 10.1016/ j.jtos.2018.01.001. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Conclusions: This large clinical study has shown that sex has a large influence on the symptomatology of DED, with significantly higher symptom scores and lower correlation between symptoms and signs in women compared to men. These findings are of importance in clinical practice and in conducting research into DED.

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“…O OSDI ® é um questionário que avalia a gravidade do olho seco através de 12 perguntas que abordam sinais e sintomas, dificuldades visuais e fatores desencadeantes na semana anterior à avaliação. Este teste foi escolhido por ser rápido, confiável e de fácil entendimento, resultando em uma pontuação mesmo que o paciente não tenha respondido a todas as perguntas (31)(32)(33) . O presente estudo avaliou subjetivamente os sintomas e objetivamente os sinais relacionados ao olho seco.…”

Section: Discussionunclassified